PubMed Health⌕ Search

Biomedical subjects

I V Reshetov

Publications and source records attributed to I V Reshetov.

At least 19 recordsLinked to original sources
PubMed2006

[Application of cell technologies to tissue defect closure in oncology].

In vivo and in vitro experiments on the application of cell technologies to tissue defect closure were conducted; autologic mesenchymal stem cells on 3-demensional matrices were used. The authors analyze the results of the application of bioengineering tissue equivalents for the closure of soft tissue and upper airway defects after extensive resections performed in 52 oncological patients. Tissue equivalents with stem cells provide engraftment and long-term graft functioning; they also modify wound surface, thus stimulating wound epithelization. In this study the application of tissue equivalents led to wound healing and functional recovery in 87% of patients.

Follow-Up Studies↗
PubMed2003

[Rehabilitation of a voice function by means of prosthetic repair of voice after removal of the larynx for cancer].

The paper presents treatment results in 223 patients who have undergone tracheoesophageal anastomosis with prosthetic repair of voice (PRV) after laryngectomy for cancer. PRV was made both simultaneously with laryngectomy (n=126) and after it (n=97). The procedure, complications and their prevention are described. The authors support the idea of the "gold standard"--voice repair for each laryngectomized patient. Tracheoesophageal anastomosis opens great prospects: loud intelligible speech recovered in 91.9% patients.

Adult↗
PubMed1999

[Microsurgical autotransplantation of organs and tissues in oncologic patients].

402 patients with tumors of the head, neck and gastrointestinal tract as well as of the locomotor system underwent microsurgical autotransplantation of tissues during the treatment and rehabilitation. 483 microsurgical autografts from fascio-cutaneous, muscular and osseous tissues were used as well as from visceral organs (the stomach, omenthum, the bowels). Successful outcomes of plastic and reconstructive operations were obtained in 95% of all the cases. Successful microsurgical plastics favoured timely application of combined antitumor treatment. In 50-60% of oncological patients a complete social and labour rehabilitation was achieved. The method proved to be perspective for further development and implementation in oncology.

Humans↗
PubMed1996

Sagittal craniosynostosis and multiple skeletal anomalies in a 3-year-old boy.

A patient with multiple congenital anomalies (sagittal craniosynostosis, complex of vertebral anomalies, additional left cervical rib at the C-7 level, common bifurcated head for the fourth and fifth left ribs, first right metacarpal hypoplasia, anomalies of the blood vessels of the upper extremities) and normal history of physical and mental development is presented.

Abnormalities, Drug-Induced↗
PubMed1996

[Autotransplantation of a double-bone-muscle-skin flap in the one-step segmental resection and plastic repair of distal segments of the extremities in cancer patients].

This article describes a biosteodermomuscular flap formation. The flap contains parts of VIII-IXribs, the broadest muscle of the back and a musculus serratus anterior. This method has been successfully used for a one-step segmental resection and microsurgical plastic operations on distal parts of extremities in five patients with malignant tumors of soft tissues.

Adult↗
PubMed1993

[Methods for increasing graft survival in esophagogastroplasty].

From their own clinical material the authors revealed that insufficient venous outflow was the main link in the pathogenesis of impaired viability of the pedicle formed from the greater curvature in esophagoplasty. This leads to circulatory disorders in the graft: venous hypertension of up to 34.4 +/- 2.3 cm inadequate perfusion of tissue, and secondary arterial hypotension below 40 mm Hg. The authors suggested an original pathogenetically substantiated method of esophagoplasty with a pedicle from the greater curvature of the stomach. Its essence consists in the creation of an additional venous outflow from the graft into the neck veins. Operations were performed on 55 patients with the formation of 70 intravenous anastomoses. The suggested method made it possible to form a longer graft and reduce considerably the number of necrotic complications in esophagoplasty. A reliable graft of sufficient length allowed the immediate and late-term results of treatment and rehabilitation of patients with esophageal carcinoma to be improved essentially.

Adult↗
PubMed1993

[Reconstructive-plastic operations using microsurgical techniques in oncology].

With the successful development of combined treatment of malignant tumors, the performance of organ-preserving operations, those with microsurgical techniques among others, is now possible. Ninety-five patients with various localization of the tumors were operated on. Esophagoplasty using a graft from the greater curvature of the stomach with venous shunting, and segmental esophagoplasty with the small intestine were conducted in 63 patients, plastics of the lower limb in 25 patients, and plastics of the organs of the head and neck in 7 patients. Vascular complications were encountered in 11.5%. The grafts healed completely in 93.7%. Preoperative radiotherapy and chemotherapy were the main complicating factors. Microsurgical techniques make it possible to expand the radicalism of the operations and improve the rehabilitation of oncological patients. Clear-cut indications for such operations must be taken properly into account.

Esophageal Neoplasms↗
PubMed1991

[Endocrine function of the pancreas after radical surgery in esophageal cancer].

Postoperative levels of insulin and morphological pattern of beta-cells of islets of Langerhans were studied in 27 esophageal cancer patients following one-stage esophageal resection or repair with the gastric pedicle graft and extracavitary cervical shunt. There is a postoperative inhibition of secretory activity of the insulin pancreatic apparatus which recovered on 120 postoperative day. These shifts resulted from dystrophy of the beta-cells.

Esophageal Neoplasms↗
PubMed1991

[Results of simultaneous resection and plastic surgery of the esophagus with extra-cavitary cervical esophagostomy in esophageal cancer in its thoracic part].

The work analyses the results of one-stage resection and plastics of the esophagus with a tube formed from the greater curvature of the stomach and creation of an ++extra-cavitary anastomosis on the neck in combined and surgical treatment of carcinoma of the thoracic esophagus in 279 patients. Various complications occurred in 181 (64.8%) patients. The mortality was 19.3% (16.8% among patients who underwent radical operation and 25.6% among those treated by a palliative operation). The number of complications in the groups of surgical and combined treatment was approximately equal. The results of 5-year survival were better in the group with combined treatment. Postponed + extra-cavitary anastomosis was formed in 65.2% of cases. One-stage resection and plastics of the esophagus with ++extra-cavitary anastomosis is an adequate operation from the oncological standpoint in the treatment of carcinoma of the thoracic esophagus. Its further perfection is necessary for improvement of the immediate and late-term results of treatment.

Adult↗
PubMed1991

[Extracavitary esophageal end-to-side anastomosis in esophagoplasty with a tube formed from the greater curvature of the stomach].

The article discusses information on experience in the formation of 367 extracavitary esophageal anastomoses in esophagoplasty with a tube formed from the greater curvature of the stomach in malignant esophageal tumors. Four main types of anastomosis were encountered: oblique--142, end to end--101, end to side--91, and atypical--33. Various complications occurred in 40.3% of patients, in end to side anastomosis in 26.3% of cases. The authors discuss in detail the operative techniques and the indications for this type of anastomosis. The authors consider it preferable to form the extracavitary esophagogastric anastomosis on the posterior wall of the transplant with a decompression stoma.

Adult↗
PubMed1990

[Polarographic evaluation of oxygen metabolism in the transplant after esophagogastroplasty].

Oxygen metabolism of a tube graft formed from the greater curvature of the stomach in esophagoplasty for carcinoma of the thoracic esophagus was studied by polarography. The study was conducted during the stages of treatment: in the early postoperative period and before the formation of a postponed extracavitary esophagogastric anastomosis. Oxygen tension (pO2) and the rate of oxygen consumption (ROC) by the graft tissue were studied. The pO2 for the isoperistaltic grafts was 65.3 +/- 2.31 mm Hg in the zone of the nutrient vessel and 51.68 +/- 11.6 mm Hg in the zone of the mechanical suture. A favourable postoperative period corresponded with a ROC of 0.1-0.2 units. The results of the study coincided with the clinical result in 86.3% of cases.

Adult↗