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Biomedical subjects

I Van Cromphaut

Publications and source records attributed to I Van Cromphaut.

3 recordsLinked to original sources

Gravitational syndrome and tensile properties of skin in the elderly.

BACKGROUND: To evaluate the influence of gravitational edema due to chronic venous insufficiency upon the tensile properties of skin. METHOD: A total of 30 women aged 66-75 years participated in the study. Evaluations were made twice in the same subjects following the use or nonuse of daytime elastic compression. Mechanical properties of the skin were measured in the midportion of the legs using a computerized suction device. RESULTS: The consistency of skin which shows abnormal rheological characteristics at the site of gravitational edema was significantly modified by compression therapy. Both skin extensibility and hysteresis were increased after wearing tight stockings although the biologic elasticity remained unchanged. CONCLUSION: Noninvasive measurements of the tensile properties of the skin represent an objective assessment of the severity of leg edema and of its correction by compression therapy.

Aged↗

[Skin microcirculation, adherence molecules and inflammatory dermatoses].

Skin is a peculiar organ with regard to its microcirculation. The dermal vasculature is enriched with abundant anastomoses. It forms a single compartment where blood can be pulsed in any direction without always following an arteriolovenular gradient. Under various pro-inflammatory stimuli, endothelial cells express diverse adhesion molecules whose specificity leads to the intradermal collection of specific leukocytic lineages. Such basic mechanism is at the origin of all inflammatory dermatoses. It is possible and even probable that some antihistamines, flavonoids and antiseptics modulate in a beneficial way the expression of some adhesion molecules.

Anti-Infective Agents, Local↗