PubMed Health⌕ Search

Biomedical subjects

I Vergara

Publications and source records attributed to I Vergara.

30 records · Page 2Linked to original sources
PubMed1992

[Polymorphic reticulosis: a type of lymphoma? Report of 3 cases].

Three patients seen at the Medicine Department of Del Salvador Hospital between 1986 and 1990 are reported. All had a history of purulent or bloody nasal discharge and recurrent sinusitis, before the appearance of progressive and painful destructive phenomena that affected the rhino faucial region. The diagnosis was made with the histopathological study that disclosed and angiocentric polymorphic infiltrates and perivascular necrosis. The three patients received similar treatment consistent in prednisone 1 mg/kg/day per os, cyclophosphamide 2 mg/kg/day per os and local radiotherapy. The response to therapy was bad and survival was less than three months. It is concluded that although this entity is infrequent, its severity requires and aggressive workup and management by a multidisciplinary team. Notwithstanding the mortality remains to be high.

Adult↗
PubMed1987

Wilson's disease, a reversible dementia: case report.

A case of advanced Wilson's disease with clear dementing features is presented. Neuropsychological evaluation before treatment revealed intellectual deterioration particularly in memory and performance tasks. The patient was treated with Penicillamine, a copper-chelating agent, for 7 months, with notable improvement in her dementia and in her motor signs. A second battery of neuropsychological tests demonstrated the improvement in the mental aspects. These findings support the concept of Wilson's disease being a reversible dementia.

Adult↗
PubMed1986

Ventral root nonmedullated fibers: proportion, calibers, and microtubular content.

Proportion, caliber, and microtubular content of the L7 ventral root nonmedullated fibers were studied in the cat. Nonmedullated fibers constituted 28% of the axonal population at the far end of the root. The number of myelinated profiles at the far end of the root and in the vicinity of the ventral surface of the cord (1-2 mm distance) was the same whereas the number of nonmedullated fibers decreased toward the proximal site of the root by 42%. Caliber and microtubular content of nonmedullated fibers were assessed only at the far end of the ventral root. Nearly 90% of the axons were smaller than 0.3 micron2. The average cross-sectional area was 0.15 micron2, a value 35% below that of the L7 dorsal root fibers. The microtubular density was highest in the finest fibers (116 microtubules/micron2 in fibers smaller than 0.1 micron2) and decreased with the increase in cross-sectional area (25 microtubules/micron2 for 0.7-0.8 micron2 axons). The number of microtubules per axon in axons of both roots was similar in fibers smaller than 0.3 micron2; in larger axons, composing about 10% of the population, ventral root fibers had more microtubules than dorsal root fibers. The ventral and dorsal nonmedullated fibers differ slightly but significantly in caliber and microtubule content. However, they are similar in contrast to peripheral nonmedullated fibers, which are three to four times as big and contain two to three times as many microtubules as radicular fibers. Our results confirm the presence of a large admixture of nonmedullated profiles in the L7 ventral root of the cat, support the notion that a number of these fibers make a U turn in the ventral root, and suggest that these arise from the central process of the primary sensory axon.

Animals↗
PubMed1985

Topography of the hemi-inattention syndrome.

The hemi-inattention syndrome was studied in 15 right-handed adults, 12 men and 3 women. One patient had a pontic-mesencephalic lesion, 3 had right hemisphere damage, 7 had left-hemisphere lesion and 4 had bilateral lesions. All lesions were confirmed by CT-scan. Different criteria of hemi-inattention were used. All patients presented extinction, inattention and in 13 visuomotor akinesia; 5 of the left and all of the right and bilateral lesion patients presented spatial neglect. CT-scans were superimposed. The posterior parietal region was the most important in producing contralateral hemi-inattention. Results are discussed with relation to the literature and the educational factor and cerebral asymmetry are discussed with regard to hemi-inattention.

Adult↗
PubMed1977

Neuroparalytic accidents of antirabies vaccination with suckling mouse brain vaccine. Clinical and pathologic study of 21 cases.

Twenty-one cases of neuroparalytic accidents of rabies vaccination (with suckling mouse brain vaccine), 11 of them fatal, were observed, occurring predominantly in men; the mean age of the patients was 29 years. On the average, 13 doses of the vaccine were used. Only three patients received less than seven doses. The mean latent period was 14 days (range, 4 to 24 days). In 16 patients (76%), a Guillain-Barré syndrome occurred that was moderate in three, severe in seven, and fatal in six. Pathologically, this was shown to be a typical polyradiculoneuritis. Five patients had fatal involvement of the central nervous system. Three had an acute disseminated perivenous leukoencephalopathy, with concurrent rabies encephalitis in one case. One patient had a perivenous myeloradiculopathy and one a chronic encephalomyelopathy of six years' duration with demyelinating plaques in the periventricular white matter, cerebellum, and spinal cord. Since the reduction of postexposure rabies vaccination to seven doses, no new cases have been observed in Colombia.

Adolescent↗