PubMed Health⌕ Search

Biomedical subjects

I W Evett

Publications and source records attributed to I W Evett.

14 recordsLinked to original sources
PubMed1992

Efficient retrieval from DNA databases: based on the second European DNA Profiling Group collaborative experiment.

We describe an experiment to investigate the potential effectiveness of an international DNA database for linking unsolved crimes using the data from a collaborative exercise among members of the European DNA Profiling Group. We show that effective retrieval of unknown samples will be feasible even from large databases provided that the conditions that were adopted for the collaborative exercise are maintained.

Bayes Theorem↗
PubMed1992

Whose DNA?

Explore the source record for details and available documents.

DNA Fingerprinting↗
PubMed1991

Trivial error.

Explore the source record for details and available documents.

DNA Fingerprinting↗
PubMed1991

DNA single locus profiles: tests for the robustness of statistical procedures within the context of forensic science.

We describe a series of experiments, carried out on data from DNA profiles, which have been designed specifically to test the validity of the statistical procedures currently used in the Home Office Forensic Science Service. The tests address issues which have been the subject of topical debate, in particular those of representativeness and band independence. The results confirm the confidence which had already been placed in the established procedures. We recommend that all practitioners in the forensic field should carry out similar testing on their own data collections.

DNA Fingerprinting↗
PubMedDate not supplied

Databases, quality control and interpretation of DNA profiling in the Home office Forensic Science Service.

The history of DNA profiling in the Home Office Forensic Science Service began with the introduction of multilocus probes into casework in 1986. The use of single-locus probes was introduced in 1990, supported by databases of three ethnic groups; interpretation is backed up using a Bayesian approach. Databases were compiled using an image analysis computing system. Quality control systems are described, detailing requirements before a sample can be included in the database.

DNA Fingerprinting↗
PubMedDate not supplied

Paternity calculations from DNA multilocus profiles.

DNA profiles prepared using multilocus probes can provide valuable evidence in cases of disputed parentage. This paper describes a simple approach to the analysis of the profiles from a mother, child and putative father in a case of disputed paternity. Although the treatment has not yet been extended to deal with cases in which mutant bands may have appeared, it has already proved useful in casework. The analysis is illustrated by a numerical example calculated on a computer spreadsheet.

Bayes Theorem↗
PubMedDate not supplied

Analysis of DNA multilocus profiles in a paternity case in which the child's profile may be partial.

This report describes a simple approach to multilocus paternity analysis for cases where the child's sample may be inadequate leading to a partial profile. A specimen calculation is given. A previous paper described how the various band sharing configurations in the DNA multilocus profiles of a mother-child-putative father trio could be combined in a comprehensive mathematical analysis to give an overall Bayesian likelihood ratio. In that paper, it was assumed that all three members of the trio gave full DNA profiles. In some cases that assumption may not be valid but it is possible to extend the analysis to allow for partial profiles. This paper demonstrates how this may be done by considering the case where the child's profile may be partial for one reason or another. A specimen calculation is given.

Bayes Theorem↗
PubMedDate not supplied

A guide to interpreting single locus profiles of DNA mixtures in forensic cases.

Analysis of a mixed body fluid crime sample by means of a single locus DNA probe may give rise to several bands. If a suspect is found to have a profile which matches two of the bands, then the evaluation of the evidential strength requires careful analysis. This paper describes the analysis of two relatively simple case examples. It is intended that the principles of the interpretative process will provide a guide to caseworkers who may encounter similar cases. The extension of the treatment to more complex cases should be clear.

Body Fluids↗
PubMedDate not supplied

Evaluating DNA profiles in a case where the defence is "it was my brother".

The widespread application of DNA profiling has brought to some prominence the issue of close relatives sharing body fluid types. In a particular crime case it may be suggested that a close relative of the suspect was the person responsible. This paper explains how an assessment may be made in the context of single locus profiling and where the suggestion is that a full sibling is involved. A formula is established for the likelihood ratio which is then worked out in detail for the particular case where the suspect profile has two distinct bands. Generalization to other types of case is briefly explained and there is a short discussion of the impact of the evidence in the context of a trial. For all parties, justice will best be done if the scientist has ample notice, before the trial, of relationship issues such as this one.

DNA Fingerprinting↗
PubMedDate not supplied

An investigation of the feasibility of inferring ethnic origin from DNA profiles.

A small experiment is described which uses databases of Afro-Caribbeans and Caucasians to establish the quality of information that might be given to an investigator about the ethnic group of the donor of an unknown crime stain. The results show that the technique can provide qualified indications, but categoric conclusions are not, in general, feasible. An appraisal is given of the technique within the operational context.

Black People↗
PubMedDate not supplied

An efficient statistical procedure for interpreting DNA single locus profiling data in crime cases.

This paper describes a simplified approach to calculating the Bayesian likelihood ratio for the case where two DNA single locus profiles are to be compared. It explains how the calculation allows for band shift and also for the variation in precision with molecular weight. A simple basic theory section explains the principles of the analysis but more detailed explanations are given in an advanced theory section. Experiments on substantial data collections are described which demonstrate the robustness of the method.

Bayes Theorem↗