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Biomedical subjects

I Wickramasekera

Publications and source records attributed to I Wickramasekera.

12 recordsLinked to original sources

Psychophysiological and clinical implications of the coincidence of high hypnotic ability and high neuroticism during threat perception in somatization disorders.

The electrodermal response to cognitive threat of unhypnotized female patients with somatic symptoms and high on both hypnotic ability and neuroticism (H-H) was found to be significantly higher (p < .01) than that of a matched group of female patients moderate on hypnotic ability and low on neuroticism (M-L). On verbal report the H-H and the M-L groups did not differ, but they were significantly different on a measure of self-deception (L scale) or repression. The above findings are consistent with predictions from the High Risk Model of Threat Perception (HRMTP), which states that people in the H-H group are both chronically and acutely more reactive to threat than the people in the M-L group. This finding may have important theoretical, clinical, and financial implications for the diagnosis, therapy, and prevention of somatization disorders seen in primary medical care.

Adult

A conditioned response model of the placebo effect predictions from the model.

A model of the placebo response as a conditioned response (CR) is presented and predictions from this model are listed. Through association with active ingredients (UCS), neutral (CS) places, persons, procedures, and things can come to acquire the ability to reduce pain, anxiety, and depressive responses. One major counterintuitive prediction from the model is that therapists who routinely use active ingredients (UCS) or powerful drugs will get stronger placebo effects than those who routinely use "inert" ingredients (CS) or weak drugs. Developmentally, placebo responding appears to involve two successive conditioning stages, which may involve first the left and later the right hemisphere in right-handed subjects. The relationship between placebo responding and hypnotizability is discussed.

Conditioning, Psychological