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Biomedical subjects

I Wilhelmsen

Publications and source records attributed to I Wilhelmsen.

5 recordsLinked to original sources
PubMed1992

[Treatment of stomach ulcer with bismuth subnitrate, oxytetracycline and metronidazole].

60 patients with recurrent duodenal ulcers were treated with bismuth subnitrate, oxytetracycline and metronidazole. Helicobacter pylori status was assessed before and after treatment by means of the 14C-urea breath test. All patients were helicobacter positive before treatment. Four weeks after cessation of therapy H pylori had been eradicated in 57 out of 60 patients (95%). The ulcer healing rate was 100% after six weeks. 43% of the patients complained of moderate to severe side effects, mainly nausea and diarrhoea, but no patients discontinued the treatment prematurely. The study indicates that nearly all patients with recurrent duodenal ulcer are infected with H pylori, and that the present triple treatment regimen is very effective both in eradicating H pylori and in healing the ulcer.

Adult↗
PubMed1992

Biometric evaluation of gastric urease activity in man.

The 14C-urea breath test is claimed to be the best test for detection of Helicobacter pylori infection. We present a procedure for estimating its cutoff value on the basis of biometric evaluation only, without involving other diagnostic methods. Cumulative gastric urease activity (CA) was determined during the first 30 min after oral administration of 14C-urea (92.5 kBq) in 56 random volunteers and 49 consecutive patients with peptic ulcer disease. The distribution of CA in random volunteers was positively skewed. Logarithmic transformation yielded two separate populations, each normally distributed. Their normal probability density functions intercepted at log cutoff value. A bimodal distribution of log CA was confirmed in patients with peptic ulcer disease before and after treatment aimed at H. pylori eradication. Cutoff values were determined for both random volunteers and patients with peptic ulcer disease. By application of the present procedure for determination of cutoff value, the 14C-urea breath test distinguishes between individuals who have an increased gastric urease activity and individuals who do not, with the smallest possible arbitrariness.

Adult↗
PubMed1990

[Cognitive therapy. Methods and applications].

Cognitive therapy is a fairly new form of psychotherapy. The article compares this form of therapy with the more common psychodynamic oriented psychotherapy on the one side and behavioural therapy on the other side. The authors define the most common terms in cognitive therapy (basic beliefs and automatic thoughts), and describe the content of the therapy. Finally they outline the areas where cognitive therapy has been proven most beneficial (treatment of depression, anxiety states, chronic pain, psychosomatics and increase in patient compliance), and discuss the future use of cognitive therapy in Norway.

Cognitive Behavioral Therapy↗