Biomedical subjects

I Wisłocka

Publications and source records attributed to I Wisłocka.

3 recordsLinked to original sources

PubMed1995

Carcionoembryonic antigen and immunoglobulin IgE in coeliac disease, food allergy and dudenal ulcer disease in children.

The aim of this study was to estimate the behaviour of carcinoembryonic antigen (CEA) and immunoglobulin IgE level in children with coeliac disease (CD), food allergy (FA) and duodenal ulcer disease (UD). In total, 390 determinations of CEA (201 for CD, 27 for FA and 162 for UD) and 558-IgE (238, 136 and 184, respectively) were carried out during disease aggravations and remissions. The analysis of CEA mean values with respect to sex revealed no differences while IgE level in boys with UD was twice as high as in girls. No differences in CEA or IgE levels were found with respect to the season of the year. The IgE concentration increased during aggravations, but only in the case of UD was the difference statistically significant. CEA behaviour was similar (statistically significant differences for CD and very significant for UD). Both values, however, were normal.

Carcinoembryonic Antigen↗

PubMed1988

Preliminary reports on hyperbaric oxygen therapy in multiple sclerosis.

Preliminary clinical examinations comprised 16 patients suffering from multiple sclerosis, the mean duration of the disease 9.33 years, of the manifestations at different stages of the development--evaluated on the basis of Kurtzke scale. The patients were subjected exclusively to the treatment with oxygen hyperbary--all in all 25-30 exposures, with the intervals of 24 hours, under the O2 pressure of 2 ata. The qualification for the purposes of treatment and the classification of the symptoms present were carried out according to Fisher, the results obtained were evaluated in conformity with standard version of the Disability Status Scale of Kurtzke. Apart from the routine clinical and laboratory tests the programme of the examinations included also a quantitative determination of immunoglobulins level, complement activity as well as the determination of T and B lymphocytes. An eminent change for the better was found in 14 afflicted persons, in one patient after 15 exposures a worsening was observed and the treatment was arrested. As to the immunological parameters investigated, a general decrease of IgG, IgM, IgA in serum, increase of the complement fraction and its 50% hemolysis determined activity were observed, whereas quantitatively investigated T and B lymphocytes did not show any typical changes. The authors discuss the results.

Adolescent↗

PubMed1987

Preliminary research on possibility of bronchial asthma treatment with hyperbaric oxygenation.

The total of the persons examined was divided into 3 groups. There were 11 men and 5 women with various diseases diagnosed in Group I, 5 healthy men in Group II and 9 man and 2 women with allergy in Group III, the control group. The subjects were treated with hyperbaric oxygenation exposures from 1.8 to 2.5 ata O2 within a 60-90 minute period. The number of exposures ranged from 1-4 for Group II till 10-15 for Group I and Group III. In all the cases the following examinations were carried out: hematological tests (Hb, Ht, erythrocytes, leucocytes, and blood platelets counts, blood picture), immunological tests (IgG, IgM, IgA, IgD, IgE, C3 fraction of complement and hematolytical activity of complement--CH50) and all required additional clinical tests. These examinations were made before the series of hyperbaric exposures, after 4 exposures, after their completion and a month later. Full documentation in Group I was obtained in 6 cases and in the 10 remaining only before the exposures and after their completion. In Group II full documentation was available only in 1 person, but before the exposures and after their completion in the rest, and finally, in Group III full documentation was obtained in 7 persons, but before the exposures and after their completion in 4 others. Generally, it was in allergic states that a positive therapeutic effect of hyperbaric oxygenation was found. It had already been corroborated by the respective shifts of immunological coefficients, noted by other authors too. The above observations need to be confirmed in a wider material, in different periods of the disease and with other additional examinations employed.

Adult↗