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Biomedical subjects

I Yada

Publications and source records attributed to I Yada.

At least 127 records · Page 7Linked to original sources
PubMed1988

[The evaluation of operability for patients with severe valvular disease].

The present study was designed to evaluate and determine the factors which affected the prognosis of the surgical patients with severe valvular diseases. Four hundred and forty six cases which underwent valvular surgery from 1977 to 1987 were used for this study. There were 16 early death cases (3.6%) and 16 late death cases (3.6%), respectively. The early death rate after surgery was significantly high in the cases which had 1) poor LV function (LVEF less than 35%), 2) liver dysfunction (T-Bil greater than 1.3mg/dl, ICG-Rmax less than 1.0 mg/kg/min, Ch-E less than 0.6PH, K-ICG 0.10/min), and/or 3) PVE after valve replacements. These factors were recognized in 9 (56.3%) of the early death cases and 10 (62.5%) of the late death cases. Thus, we consider that these factors affect the surgical prognosis and that the border line values for the factors are: 1) LVEF less than 0.3%, LVDI greater than 40 ml/m2 in MS group and 50 mg/m2 in other valvular groups. 2) T-Bil greater than 2.7 mg/dl, ICG-Rmax less than 0.5mg/kg/min in cardiac cachectic cases, and 3) active PVE cases which showed drug-resistance. Furthermore, these values should be corrected by IVH and immunosupportives during the pre- and post-operative periods.

Adolescent↗
PubMed1985

Two-dimensional echocardiographic evaluation of right ventricular function during left heart bypass.

Right ventricular (RV) function in terms of hemodynamics and RV wall motion was studied in 14 mongrel dogs during left heart bypass (LHB) using a centrifugal blood pump. The wall motion was analyzed by two-dimensional echocardiography (2D-echo). Incremental changes in LHB flow ratios of 0% (controls), 25%, 50%, 75% and a maximum 85-100% were accompanied by decrements of segmental shortening of the interventricular septum (IVS) by 54 +/- 12%, 43 +/- 5%, 42 +/- 2%, 35 +/- 0% and 0%, respectively. In addition to akinesis of the IVS during maximum flow, a specific part of the RV free wall adjacent to the IVS also had marked depression of contractions and overall RV contraction was nearly dependent on the RV free wall opposite to the IVS. Maximum LHB flow induced complete depression of the left ventricular cavity, a marked increase in RV volume, and depression of the RV ejection fraction on 2D-echo. Excessive or prolonged LHB reduces the RV wall motion capability and may lead to right heart failure. Our results suggest that an LHB ratio of about 75% is optimum to maintain normal cardiac function, particularly that of the right heart.

Animals↗