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Biomedical subjects

I Zrara

Publications and source records attributed to I Zrara.

13 recordsLinked to original sources

[Segmental renal hypoplasia or Ask-Upmark kidney -- anatomopathologic approach: report of 2 cases].

Segmental renal hypoplasia or Ask-Upmark kidney is an extremely rare anomaly that induces severe arterial hypertension in young patients. Two new cases of this entity are presented respectively in a 39 and 31 years old women who are admitted for hematuria, elevated blood pressure level and flank pain. Surgical treatment of the hypoplasia kidney permitted successful treatment of the high blood pressure with preservation of renal function and flank pain. In view of the literature, the authors discuss the pathogenic, diagnostic and therapeutic aspects of this condition.

Adult↗

Cerebellar liponeurocytoma (lipomatous medulloblastoma).

Liponeurocytoma (lipomatous medulloblastoma) is an uncommon clinicopathologic entity. We report a case of cerebellar liponeurocytoma in an adult and attempt to better characterize this uncommon lesion. A 43-year-old woman presented with symptoms and signs of increased intracranial pressure and cerebellar dysfunction. CT and MRI showed a heterogeneous well-circumscribed mass in the left cerebellar hemisphere with hydrocephalus. Complete surgical excision of the tumor was accomplished through a suboccipital craniotomy. Pathological examination with immunohistochemical study revealed a medulloblastoma with neuronal, astrocytic and lipomatous differentiation. Postoperative radiation therapy was given. After surgery, the patient was followed up for a 16 month-period; symptoms improved dramatically and no evidence of tumor recurrence was found. Careful analysis of the histopathological and immunohistochemical studies correctly identifies liponeurocytoma (lipomatous medulloblastoma). To our knowledge, only 16 cases have been reported. Although this lesion appears to have a better prognosis than the conventional form of adult medulloblastoma, complete surgical removal with postoperative radiation therapy is recommended.

Adult↗

[Botryoide sarcoma of the uterine cervix. Apropos of 1 case].

Sarcoma botryoide (SB), a variant of rhabdomyosarcoma, is a rare tumor who are rarely localized in the uterine cervix. Only 99 cases have been described to date. The authors reported this case with review of the literature in order to insist on diagnosis progress and a new combined modality approach using: radiotherapy, surgery and chemotherapy which have improved prognosis in the localized disease especially.

Adult↗

[Multiocular renal cysts in adults. Two case reports].

The authors report two cases of renal multilocular cyst and review the cases reported in the literature, revealing the original features of this benign tumour which has an equal incidence in children and adults with a controversial acquired or malformative aetiopathogenesis, precise histological features, but a difficult preoperative and intraoperative diagnosis despite modern imaging techniques. In the great majority of cases, treatment consists in nephrectomy.

Adult↗

[Spontaneous perirenal hematomas. Report of 3 cases].

Spontaneous retroperitoneal hemorrhage is an uncommon affection, the diagnosis was recognized by sonography and CT scan, but the etiology remains unknown and exploration for diagnosis may become necessary. In the absence of an apparent etiology, patients with spontaneous renal bleeding should undergo radical nephrectomy, because of the extremely high incidence of small undetectable occult tumors. Three further cases were reported by the authors, who made a review of the literature.

Adult↗

[Aglomerular segmental hypoplasia of the kidney: report of a clinical case].

Aglomerular segmental hypoplasia of the kidney is a disease that is uncommon in the adult; the average age at appearance of symptoms is between ten and 15 years. A clear female predominance has been noted, and this disease is often misdiagnosed as chronic pyelonephritis. However, the radiological and pathological characteristics are different to the latter. The etiology of aglomerular segmental hypoplasia has not yet been determined. It is important to acquire further knowledge regarding this disease, as in certain cases this information could help to avoid unnecessary nephrectomy.

Adult↗

[Pyelocolic fistula: a case study].

In this study, the case has been reported of a left renocolic fistula that was detected in a patient with hepatitis C and cirrhotic complications who was hospitalized for urogenital tuberculosis. It was decided to perform left nephrectomy and digestive suture, but surgery was delayed due to hemostatic abnormalities and massive cytolysis, and the patient died before surgical treatment, three days after the discovery of the fistula. The findings in the literature have been reviewed, and the common occurrence of this type of fistula has been underlined. They are the most frequently encountered type with of entero-urinary fistula, and account for 60% of documented cases. Their etiological and clinical characteristics of have been described in detail. In general, treatment consists of performing a nephrectomy and digestive suture.

Fatal Outcome↗

[Nodular fasciitis or pseudosarcoma].

Nodular fasciitis is a benign neoplastic and reactive proliferation of fibroblasts of soft tissues, which is often mistaken for a sarcoma because of its rapid growth, rich cellularity and mitotic activity. A case is reported that provides the opportunity to discuss the specific clinical and pathological features of nodular fasciitis.

Adult↗

[Cutaneous blastomycosis revealing a corticoadenoma].

BACKGROUND: Blastomycosis is an uncommon chronic granulomatosis caused by Blastomyces dermatitidis. We present a case with a skin localization that disclosed malignant corticoadenoma. CASE REPORT: A 32-year-old man consulted for inflammatory nodules of the face and lower limbs. The histological examination of a nodule biopsy was in favour of blastomycosis. Ketoconazole treatment was ineffective. Amphotericin B provided cure of the skin lesions. Search for extension disclosed a malignant corticoadrenoma. DISCUSSION: Blastomycosis is very rare in Morocco. The portal is usually the lung. Unique skin involvement is very exceptional. To our knowledge this is the first report of a blastomycosis-corticoadenoma association. The clinical situation may be alarming in immunodepressed subjects. Amphotericin B treatment is indicated.

Adrenal Cortex Neoplasms↗

[Myxoid liposarcoma of the spermatic cord].

A case of myxoid paratesticular liposarcoma in a 68-year old patient is reported. The evolution was normal during the follow-up period (22 months). Scrotal liposarcoma is a rare tumour: less than 100 cases were reported in literature. The diagnosis is difficult, clinical and radiological signs are the same as those of any intrascrotal tumour. Orchidectomy is the usual treatment, prognosis depends on the histological features, it is usually better than that of other paratesticular sarcomas. It did not need any additional treatment.

Aged↗

[Testicular metastasis of prostatic adenocarcinoma: report of 2 cases].

Prostatic carcinoma metastasizing to the testis is an extremely rare occurrence. In this study, two new cases have been reported of unilateral testicular metastases from an adenocarcinoma of the prostate. Unlike primary tumors of the testis, this type of tumor develops later in life (between 50 and 60 years of age), and is in most instances unilateral. It is generally discovered accidentally during orchiectomy or autopsy. It is not always easy to establish a morphological diagnosis, as the macroscopic appearance of the tumor may be normal. However, microscopic investigation reveals the presence of neoplasms of the testis.

Adenocarcinoma↗

[Iatrogenic cervicofacial hydatid cysts. Apropos of a case].

The writers give an account of a cervicofacial hydatid dissemination case, provoked by iterative ponctions of hydatid cyst initially isolated in the left maxillary sinus. They state diagnostic and therapeutic difficulties sometimes found and they insist on the role that must be played by immunologic tests in diagnostic approach and treatment monitoring of this disease which is unfortunately current and serious.

Ear Diseases↗

[Small cell carcinoma of the prostate. Apropos of a case].

Small cell carcinomas of the prostate are rare. These tumors exhibit morphologic and functional neuro-endocrine characteristics. They are a highly aggressive. New therapeutic protocols are being developed in order to be effective against these tumors, particularly those unresponsive to hormonotherapy.

Carcinoma, Small Cell↗