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Biomedical subjects

Ia E Ekha

Publications and source records attributed to Ia E Ekha.

At least 19 recordsLinked to original sources
PubMed2002

[Changes of parameters of the functional state of the organism and oxidative stress in patients after surgical revascularization at early stage of restorative treatment].

Early complex restorative treatment with individualized aerobic physical exercise in 2-4 weeks after surgical myocardial revascularization significantly increased physical working capacity and cardiorespiratory reserve of the body. Pronounced oxidative stress which had been present after myocardial revascularization decreased under the action of restorative therapy. Most pronounced increases of total physical capacity and cardiorespiratory reserve and lowering of oxidative stress occurred in patients with lowest initial parameters of the functional state of the organism.

Aged↗
PubMed1987

[Long-term prognosis of myocardial infarct patients after intracoronary thrombolytic therapy].

One hundred and thirty-nine patients with acute myocardial infarction (MI) were followed up for 4 to 48 months after intracoronary thrombolysis. Postinfarction cardiovascular function was better in patients subjected to aortocoronary shunting or transcutaneous transluminal coronary angioplasty after antegrade blood flow recovery by thrombolysis. They had a significantly lower incidence of anginal pains, better working capacity and smaller MI recurrence rates. Effective intracoronary thrombolysis alone, unassisted by the elimination of residual stenosis, failed to produce basic improvement in subjective as well as objective postinfarction condition of the patients who remained at high risk for repeated MI due to a coronary re-occlusion.

Acute Disease↗
PubMed1986

[Repeat percutaneous transluminal angioplasty in coronary artery restenosis].

Early experience with repeat transcutaneous transluminal coronary angioplasty (TTCA) in 9 coronary patients is reviewed. The interval between the first and the repeat TTCA varied between 1 and 12 months averaging 4.9 +/- 4.7 months. Repeat dilatation of the anterior interventricular branch was performed in 7 patients, that of the right coronary artery, in 1, and that of the circumflex artery, in 1. All repeat operations were successful. Changes in the degree of stenosis and the mean arterial blood pressure gradient were actually similar in both dilatations.

Angioplasty, Balloon↗
PubMed1984

[Results of using percutaneous transluminal coronary angioplasty in patients with stable and unstable angina pectoris and acute myocardial infarct].

Transcutaneous transluminal coronary angioplastics (TTCA) was performed in 28 coronary heart disease patients (8 patients had stable and 5 others labile angina, 15 presented acute myocardial infarction, AMI). The patients with AMI received intracoronary thrombolytic treatment prior to TTCA. Successful dilatation was performed in one patient with narrowing of the main trunk of the left coronary artery, in 14 of 21 patients with the stenosis of the anterior interventricular branch and in 5 of 6 patients with the narrowing of the right coronary artery. In three cases TTCA was carried out in the presence of the occluded coronary artery, with two patients benefiting from the operation. In 5 patients with AMI in whom an attempt to dilate the lumen of the coronary artery was unsuccessful, emergency surgery for aorto-coronary shunting was conducted. This operation was also performed in the planned order in 2 angina patients. In 7 patients the failure of TTCA was explained by the impossibility to pass the dilatary sound through the stenosis of the coronary artery and in 1 case by the failure to enter the ostium of the left coronary artery with the guiding catheter.

Adult↗
PubMed1984

[Use of percutaneous transluminal coronary angioplasty in treating acute myocardial infarct patients].

Transcutaneous transluminal coronary angioplastics was performed in 8 patients with acute myocardial infarction. In five patients dilatation of the coronary artery was carried out after intracoronary thrombolytic therapy and in the 3 others without the preliminary infusion of streptokinase. The method proved effective in 6 out of the 8 patients: the diameter of stenosis of the coronary artery decreased on the average from 70.4 +/- 3.9 to 23.5 +/- 12.9%, the area of stenosis reduced from 91.1 +/- 2.3 to 40.8 +/- 12.9%. Control angiography conducted in 4-5 weeks showed that in all five patients examined, the effect of the dilatation persisted. An improvement of the contractile function of the left ventricle was also observed.

Adult↗
PubMed1984

[Effectiveness of treatment of patients with acute myocardial infarction by intracoronary administration of nitroglycerin and streptokinase].

The intracoronary administration of nitroglycerin and streptokinase was assigned to 95 patients with acute myocardial infarction. In 69 (79.3%) out of the 87 occluded coronary arteries the antegrade blood flow was restored. After the thrombolysis, aortocoronary shunting was performed in 26 patients and transcutaneous transluminal coronary angioplastic surgery in five patients. In 71 patients control angiographic examination was carried out 17-185 days later. It was revealed that in 73.7% of drug-treated patients, the antegrade blood flow was retained for an average of 37 days. Patients with the intact coronary blood flow after the thrombolysis exhibited a positive pattern of the parameters of left ventricular contractile function which was especially expressed following aortocoronary bypassing. In cases of thrombolysis failure or reocclusion, left ventricular contractility had a negative profile.

Adult↗
PubMed1984

[Functional state of the cardiovascular system in patients with chronic coronary insufficiency 12 months after direct myocardial revascularization depending on the bypass patency].

A comparative study of the functional state of the cardiovascular system (CVS) in the presence of chronic heart failure was performed 12 months following direct myocardial revascularization. It involved 49 patients with open aortal coronary bypasses and 20 patients with bypass occlusion. The CVS functional state was assessed by both invasive and noninvasive methods of investigation. The bypass patency was associated with an improvement in the patients' subjective conditions, an increased exercise tolerance and better indices of the left ventricle function. It is inferred that successful revascularization of the myocardium by an aortal coronary bypass produces a considerable therapeutic effect on the CVS functional state in patients with chronic heart failure.

Adult↗
PubMed1983

[Selective thrombolytic patency of the coronary arteries in patients with acute myocardial infarction].

Urgent selective coronarography followed by intracoronary infusion of nitroglycerin and streptokinase (2000-4000 U/min) was performed in 24 patients with acute myocardial infarction. Mechanical recanalization of an occluded coronary artery was also performed in two patients. The coronary artery supplying the infarcted area was occluded in 22 patients while 2 patients had third-degree stenosis. Following intracoronary drug infusion, antegrade flow was recovered completely in 16 of 22 occluded coronary arteries (72.7%). All patients, however, retained acute coronary arterial stenosis around former occlusions. Aortal-coronary shunting was performed within 1 to 20 days in 6 patients.

Adult↗
PubMed1982

[Significance of postextrasystole potentiation in the preoperative assessment of the reversibility of left ventricular asynergy in ischemic heart disease].

The influence of post-extrasystolic potentiation of asynergy of the left ventricle of the heart has been analysed in 89 patients with ischaemic heart disease. Left ventriculography and coronarography after Judkins was performed in all the patients. It was established that asynergy of the left ventricle of the heart as a result of the post-extrasystolic potentiation became normal in 37.5% of cases and was reversible in 55.6% of cases. With initial hypokinesia normalization was seen more often (in 70%), with akinesia it was seen less often (18.8%). Dyskinesia never disappeared. Patients, having survived myocardial infarction, showed improvement in asynergia 3.2 times more rarely than those who had had no infarction.

Cardiac Complexes, Premature↗
PubMed1982

[Results of emergency coronary angiography and left ventriculography in acute coronary circulation disorders].

The results of urgent coronarography and ventriculography in 95 patients with pre-infarction state and acute myocardial infarction are analyzed. It is established that from the beginning of the acute anginal attack till the end of coronarography 13 h 40 min (average) have elapsed. In 13 patients angiographically normal coronaries have been found, 2 of them had myocardial infarction. It is recorded that in patients with pre-infarction state and acute myocardial infarction the affection of the coronaries is more severe than in those with stable angina pectoris. Coronary vessels fit for revascularization of the myocardium were found in 71.4% of patients. Disorders of contractility of the left ventricle were seen in 81.6% of cases.

Adult↗
PubMed1980

[External respiratory changes in angiographically established coronary sclerosis].

Information on the functional condition of external respiration in 101 patients with angiographically demonstrated coronary sclerosis is analysed. Definite connections between the findings of coronarography and the values of external respiration were found, which were indicative of increase in the ratio of the residual pulmonary volume to the total pulmonary capacity and of a relative hyperventilation of the lungs in the contingent examined. The discrepancy between ventilation of the lungs and their perfusion was more marked in patients with a greater number of stenosed coronary arteries. Shortening of the absolute values and the absence of an increase in the duration of repeated apnoea were evidence of insufficient resistance to hypercapnia and hypoxia during apnoea.

Adult↗