Biomedical subjects

Ian Harris

Publications and source records attributed to Ian Harris.

10 recordsLinked to original sources

PubMed2006

Retrograde nailing versus fixed-angle blade plating for supracondylar femoral fractures: a randomized controlled trial.

BACKGROUND: A variety of devices have been used in the treatment of supracondylar femoral fractures. The condylar blade plate relies on the principles of open reduction, absolute stability and interfragmentary compression to achieve union. The technique of retrograde nailing uses indirect reduction of the metaphyseal fracture component, offering relative stability and a less invasive approach. Randomized comparison of these common methods of fixation has not been reported. METHODS: Twenty-two patients with 23 supracondylar femur fractures were recruited from two regional trauma centres over a 26-month period and randomized to receive either a retrograde intramedullary nail fixation (IM group, 12 fractures) or a fixed-angle blade plate fixation (BP group, 11 fractures). The groups were followed for 12-36 months. The primary outcome measures were revision surgery and general health. RESULTS: Three patients in the IM group required revision surgery for the removal of implant components. No reoperations occurred in the BP group. There was a trend towards greater pain in the IM group, although there was no statistically significant difference in the scores for any of the SF-36 domains. CONCLUSION: Both distal femoral nailing and blade plating give good outcomes. There is a trend for patients undergoing retrograde nailing to complain of more pain and to require revision surgery for removal of implants.

Aged↗

PubMed2005

Association between compensation status and outcome after surgery: a meta-analysis.

CONTEXT: Compensation, whether through workers' compensation or through litigation, has been associated with poor outcome after surgery; however, this association has not been examined by meta-analysis. OBJECTIVE: To investigate the association between compensation status and outcome after surgery. DATA SOURCES: We searched MEDLINE (1966-2003), EMBASE (1980-2003), CINAHL, the Cochrane Controlled Trials Register, and reference lists of retrieved articles and textbooks, and we contacted experts in the field. STUDY SELECTION: The review included any trial of surgical intervention in which compensation status was reported and results were compared according to that status. No restrictions were placed on study design, language, or publication date. Studies were selected by 2 unblinded independent reviewers. DATA EXTRACTION: Two reviewers independently extracted data on study type, study quality, surgical procedure, outcome, country of origin, length and completeness of follow-up, and compensation type. DATA SYNTHESIS: Two hundred eleven studies satisfied the inclusion criteria. Of these, 175 stated that the presence of compensation (workers' compensation with or without litigation) was associated with a worse outcome, 35 found no difference or did not describe a difference, and 1 described a benefit associated with compensation. A meta-analysis of 129 studies with available data (n = 20,498 patients) revealed the summary odds ratio for an unsatisfactory outcome in compensated patients to be 3.79 (95% confidence interval, 3.28-4.37 by random-effects model). Grouping studies by country, procedure, length of follow-up, completeness of follow-up, study type, and type of compensation showed the association to be consistent for all subgroups. CONCLUSIONS: Compensation status is associated with poor outcome after surgery. This effect is significant, clinically important, and consistent. Because data were obtained from observational studies and were not homogeneous, the summary effect should be interpreted with caution. Compensation status should be considered a potential confounder in all studies of surgical intervention. Determination of the mechanism for this association requires further study.

Compensation and Redress↗

PubMed2005

Institutional practice guidelines on management of pelvic fracture-related hemodynamic instability: do they make a difference?

BACKGROUND: The management of patients with hemodynamic instability related to pelvic fracture is a major challenge, with high morbidity and mortality. Evidence-based institutional practice guidelines (PG) were developed as a strategy to optimize the care of these patients. The aims of this study were to evaluate the adherence to the new PG and compare the outcomes before and after their implementation. METHODS: Major blunt trauma patients (Injury Severity Score [ISS] > 15) with hemodynamic instability (initial base deficit > 6 mEq/L or received > 6 units of packed red blood cells [PRBCs] during the first 12 hours) related to pelvic fracture were investigated. Patients presenting with ongoing bleeding from other regions or with severe head injury (Glasgow Coma Scale score < 9) were excluded. The pre-PG group (n = 17) were patients managed during the 18 months ending on December 31, 2001. The post-PG group (n = 14) consisted of patients managed during the subsequent 18 months. Demographics, ISS, shock severity, resuscitation, and outcome data were prospectively collected. The adherence to the key steps of PG was evaluated retrospectively in the pre-PG and prospectively in the post-PG group, including abdominal clearance (AC) with diagnostic peritoneal aspiration/lavage or ultrasound (<15 minutes), noninvasive pelvic binding (PB) (<15 minutes), pelvic angiography (PA) (<90 minutes after admission), and minimally invasive orthopedic fixation (MIOF) (<24 hours). Data are presented as mean +/- SEM or percentages. RESULTS: The pre-PG and post-PG groups were similar regarding age (40 +/- 4 years vs. 42 +/- 6 years), gender (both 71% male), ISS (39 +/- 3 vs. 37 +/- 4), admission base deficit (9 +/- 1 vs. 10 +/- 1) admission systolic blood pressure (116 +/- 7 vs. 112 +/- 6 mm Hg), Glasgow Coma Scale score (12 +/- 1 vs. 12 +/- 1), and PRBC transfusion in the first 12 hours (9 +/- 2 U vs. 9 +/- 2 U). The adherence to the guidelines in the post-PG period was as follows: AC, 100%; PB, 86% (p < 0.05 based on t test or chi test); PA, 93% (p < 0.05 based on t test or chi test); and MIOF, 86%. In the pre-PG period, adherence to the guidelines was as follows: AC, 65%; PB, 0%; PA, 30%; and MIOF 52%. In the post-PG period, the 24-hour PRBC transfusion decreased from 16 +/- 2 U to 11 +/- 1 U and the mortality decreased from 35% to 7% (p < 0.05 based on t test or chi test for both). CONCLUSION: The adherence to the PG as a reflection of optimal management was significantly improved. PG focusing particular on timely hemorrhage control reduced the 24-hour transfusion requirements and the mortality rate in the post-PG group.

Adult↗

PubMed2005

Assessing leg length discrepancy after femoral fracture: clinical examination or computed tomography?

INTRODUCTION: Femoral shaft fractures treated with intramedullary nailing often heal with a leg length discrepancy (LLD). LLD is commonly evaluated by clinical examination and computed tomography (CT) scanogram. We assessed the correlation between these two techniques of calculating LLD. METHODS: We reviewed 35 skeletally mature patients who sustained a femoral shaft fracture between January 1997 and December 1999. Leg length was measured clinically with direct measurement and a block test. Each patient was asked whether they felt they walked with a limp and whether they felt they had a leg length discrepancy. Each patient underwent a CT scanogram to measure femoral and total leg length. The correlation between clinical examination and scanogram was analysed using the Pearson Product Moment Correlation. RESULTS: Of the 35 patients, 15 patients (43%) had a measurable LLD. There was a positive correlation between direct leg length measurement and the block test (P = 0.003), and between the block test and patient perception of limp and LLD. CT scanogram was performed on 29/35 patients. There was no correlation between CT scanogram and clinical measurement of leg length or between CT scanogram and patient perception of LLD or limp. DISCUSSION: Leg length discrepancy commonly occurs following treatment of femoral shaft fractures. We found that there was a strong correlation between direct leg length measurement and the block test, and between both methods of clinical leg length measurement and patient perception of a limp or LLD. Our study found no correlation between CT scanogram and clinical leg length measurement or patient perception of limp or LLD. CONCLUSION: Our study shows that physical examination (direct measurement and the block test) is more reliable and clinically relevant than CT scanogram measurement in the assessment of LLD after femoral fracture.

Adolescent↗

PubMed2005

Reoperation rate in diaphyseal tibia fractures.

BACKGROUND: Tibia fractures often require secondary surgery to achieve union. Reoperation is an objective outcome measure that is clinically relevant to the patients and treating doctors. This study determined the complication and reoperation rates for diaphyseal tibia fractures and identified variables predictive of reoperation. METHODS: One-hundred and sixty-seven patients with 175 consecutive tibia shaft fractures (Association for the Study of Internal Fixation classification 42) presenting between July 2000 and June 2003 were included in the study. There were 4 deaths and 12 patients lost to follow up. The remaining 151 patients (159 fractures) were reviewed at a minimum of 6 months post-injury for the main outcome measures; union and reoperation. Univariate and multivariate analyses by logistic regression were used to identify any relationship between revision surgery and fracture classification, grade of the soft-tissue injury, mechanism of injury, age, sex, and treating surgeon. RESULTS: The overall reoperation rate was 35.8% (57/159) with 13.2% (21/159) tibiae requiring minor revision surgery and 22.6% (36/159) tibiae requiring major revision surgery. Thirteen (8.2%) patients underwent major revision surgery specifically for non-union. The fracture classification and the Gustilo grade of soft-tissue injury were significant predictors of revision surgery overall, and of major revision surgery. CONCLUSIONS: Tibial shaft fractures have a high revision rate as a consequence of non-union and infection. Revision surgery is best predicted by the fracture classification and the severity of the soft-tissue injury. This information is important for patient information and clinical decision making.

Adolescent↗

PubMed2004

Hemodynamically unstable pelvic fractures: recent care and new guidelines.

Consistent care of hemodynamically unstable pelvic fracture patients is a major management issue. It was uncertain whether the introduction of newly developed clinical practice guidelines would require much change in current delivery of care at our institution. Assessment of recent care was undertaken and compared with the newly developed evidence-based best practice guidelines. A multidisciplinary project team developed clinical practice guidelines for determination of early optimum management of hemodynamically unstable patients with pelvic fractures. The guidelines recommend a definitive management plan to arrest hemorrhage within 30 minutes. Intra-abdominal hemorrhage should be assessed with diagnostic peritoneal aspiration (DPA) and/or focused assessment with sonography for trauma (FAST). Early noninvasive stabilization of the pelvis followed by angiography within 90 minutes are recommended if intra-abdominal hemorrhage is not found. Recent care was assessed in a historical cohort of patients, identified in a prospectively maintained trauma registry, between June 1999 and December 2001. Investigations, interventions, and times were then compared with the new guidelines. The delivery of care to 30 patients (mortality 37%, mean ISS 37.8 +/- 20.9) was studied. Compared with the new guidelines, the abdominal assessment rate with DPA and/or FAST was 53% and early (< 90 minutes) angiography rate was 38%. A form of pelvic external stabilization was applied in 27% of cases. Noninvasive pelvic stabilization was not performed at all. The recent care of hemodynamically unstable pelvic fracture patients was not in line with newly developed guidelines. There is an opportunity to markedly improve the rates of initial assessment of the abdomen, pelvic stabilization, and early angiography.

Adult↗

PubMed2004

Accuracy of mandatory surgeon recording of unplanned return to theatre.

BACKGROUND: Unplanned return to theatre (URTT) is a common performance indicator in surgery. The aim of this study is to determine the accuracy of recording URTT in orthopaedic surgery, and whether it is improved when recorded by the operating surgeon. METHODS: All orthopaedic URTT at St. George Hospital (Kogarah, Australia), as recorded by nursing staff, from 1 January 2001 to 31 December 2001 were reviewed. The results were compared to a similar review for the period from 1 June 2002 to 31 May 2003, when data was entered by the operating surgeon. RESULTS: In 2001, the true URTT rate was 68 out of a total of 2250 cases. Only 39 of these were recorded as URTT (sensitivity = 57%). Of the 2182 remaining cases, 34 were incorrectly reported as URTT (specificity = 98.4%). In the period June 2002-May 2003, the true URTT rate was 25 out of 2119 cases. Of these, 22 were correctly recorded (sensitivity = 88%). Of the 2094 remaining cases, 16 were incorrectly recorded as URTT (specificity = 99.2%). The differences in sensitivity and specificity between the two periods were statistically significant. CONCLUSIONS: Unplanned return to theatre cases need to be reviewed individually to assess clinical significance. Mandatory surgeon reporting significantly increases the accuracy of data.

Chi-Square Distribution↗

PubMed2004

Guidelines for the management of haemodynamically unstable pelvic fracture patients.

BACKGROUND: Haemodynamically unstable pelvic fracture patients have a high mortality, and decision-making is crucial. The present article discusses key clinical practice guidelines and options in the early management of these challenging patients. METHODS: A multidisciplinary consensus committee developed guidelines following standard scientific methodology, comprehensive Medline searches and level of evidence grading. Clinical practice guidelines and options addressed four key questions: (i) how to determine the source of haemorrhage?; (ii) how to control haemorrhage?; (iii) what is the optimal angiography and embolization technique?; and (iv) what is the optimal pelvic stabilization technique? RESULTS: The consensus best evidence recommends that the source of intra-abdominal haemorrhage should be assessed using diagnostic peritoneal aspiration and/or focused abdominal sonography in trauma within 30 min of patient arrival. Immediate laparotomy and concomitant pelvic stabilization control intra-abdominal haemorrhage and venous pelvic haemorrhage, followed by angiography if pelvic arterial bleeding is also present. If intra-abdominal bleeding is absent, non-invasive pelvic stabilization and transfer to angiography within 45 min of arrival is recommended to control venous and arterial pelvic haemorrhage. Optimal embolization is performed with steel coils or Gelfoam (Pharmacia & Upjohn, Peapack, NJ, USA) suspension. The optimal pelvic stabilization technique for rotationally unstable fractures with haemodynamic instability is non-invasive. CONCLUSION: The consensus committee successfully developed best evidence recommendations identifying the issues and providing guidelines and options for this challenging condition.

Algorithms↗

PubMed2003

Outcome after intramedullary nailing of femoral shaft fractures.

BACKGROUND: The results of intramedullary nailing of femoral shaft fractures from Australian institutions have not been widely reported. This study examines a consecutive group of patients treated at a major metropolitan trauma centre and reports on the injury statistics and outcome data, and compares this to previously reported results from the literature. METHODS: A total of 101 fractures in 97 consecutive adult patients were included in the study. Nine patients were excluded. At a minimum of 6 months post injury, 54 patients were interviewed by telephone and 35 patients presented for clinical review and underwent physical examination, computed tomography (CT) scanogram of the lower limbs and Short Form 36 questionnaires. RESULTS: Road trauma accounted for 81% of injuries and 15% of fractures were open. Of the 54 patients reviewed, 13 (23%) required further surgery for delayed or non-union. Of the 35 who presented for physical examination, there was poor correlation between perceived leg length discrepancy and measured leg length discrepancy on examination or scanogram. Presence of a limp correlated with measured leg length discrepancy of more than 1 cm but did not correlate with rotational abnormality measured on CT scanogram. Pain at the hip, thigh or knee was present in 60% of patients. The Short Form 36 scores for physical functioning, role--physical, bodily pain, general health and vitality were all significantly lower than population norms with P values ranging from <0.001-0.05. Subgroup analysis comparing isolated femur fracture to multi-trauma patients for all five of these parameters revealed significant differences only in the multi-trauma group. CONCLUSION: The incidence of pain, limp, leg length discrepancy and delayed or non-union is higher in this study than in previously reported results of intramedullary nailing for femoral shaft fractures. This may be due to differences in the patient population, the skill level of the operating surgeon, or incomplete follow up.

Adolescent↗

PubMed2002

Radiation exposure using laser aiming guide in orthopaedic procedures.

BACKGROUND: Ionizing radiation from intraoperative fluoroscopy presents a serious occupational health and safety concern to orthopaedic surgeons.The long-term effects of ionizing radiation are well known; they include damage to the eyes, increased risk of haematological malignancy and carcinomas throughout the body. We studied the effect of using an attachable laser aiming guide on radiation exposure during intraoperative fluoroscopy. METHODS: A prospective, randomized controlled trial was performed at a single institution. Eight hundred and eighty consecutive orthopaedic procedures involving fluoroscopy were randomized into two groups. One group had fluoroscopy without an aiming guide, the other group had fluoroscopy with the aiming guide. Total exposure time, number of exposures and the body region examined were recorded. RESULTS: For most regions studied, no significant difference in exposure time or number of exposures was found. For hip fractures, use of the laser aiming device was associated with an increase in the number of exposures (P = 0.035), but there was no significant difference in average exposure time (P = 0.31). Use of the aiming device was associated with an increased number of exposures (P = 0.0025) and an increased exposure time (P = 0.0016)for examination of the wrist, but this may represent selection bias. CONCLUSION: Use of a laser aiming device during intraoperative fluoroscopy was not associated with decreased exposure to radiation.

Fluoroscopy↗