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Ibrahim Mansoor

Publications and source records attributed to Ibrahim Mansoor.

14 recordsLinked to original sources
PubMed2003

Analysis of inconclusive fine-needle aspiration of thyroid follicular lesions.

To evaluate all inconclusive fine-needle aspiration biopsy (FNAB) specimens from thyroid follicular lesions with subsequent histologic diagnosis at St John Hospital and Medical Center, Detroit, MI. The criterion for specimen adequacy used in our institution was also reexamined to determine whether it was too stringent. We reviewed 45 inconclusive FNAB samples. Only cases that underwent surgical intervention were considered. Specimen adequacy was determined by the presence of at least 8-10 tissue fragments of well-preserved follicular epithelium on at least two slides; each tissue fragment should have a minimum of 8-10 cells. Different cytologic characteristics-cellularity, cellular architecture, nuclear pleomorphism, inclusion/grooves, chromatin, Hürthle cell change, lymphocytes, macrophages, colloid, and multinucleated giant cells-were scored and compared with final surgical diagnosis. The surgical procedure performed was also analyzed. Review of these 45 surgical specimens found 28 (62.2%) multinodular goiters, 14 (31.1%) nodular hyperplasias, 2 (4.4%) follicular adenomas, and one (2.2%) with invasive follicular carcinoma. Forty-three (95.6%) of these cases were female and 2 (4.4%) were male. Cytologic review showed 2 acellular samples, 10 cases containing macrophages only, 10 aspirates with macrophages and an inadequate number of follicular cells, and 23 specimens with an inadequate number of follicular cells. Twenty-three patients underwent total thyroidectomy; 20, lobectomy; and 2, isthumusectomy. Almost 98% of the patients with inconclusive FNAB had benign lesions. This finding encouraged us to continue using our criteria for adequacy because of the importance of a negative report. Patients in our series, who underwent thyroidectomy after an inconclusive or nondiagnostic aspirate, had a malignancy rate of 2.2%, which was no worse than patients with a benign preoperative diagnosis. A balanced approach with careful follow-up for nondiagnostic cytology is prudent.

Adult↗
PubMed2002

Histopathological and immuno-histochemical characteristics of primary renal primitive neuroectodermal tumor.

We report a 32-year-old male who presented with huge (17 x 10.5 x 5 cm) right kidney with metastasis in the liver and retroperitoneal lymph nodes. Histological, detailed immunohistochemical studies and electron microscopic examinations were performed. Microscopy revealed small to intermediate sized cells with hyperchromatic nuclei, scanty cytoplasm, abundant mitosis with no pseudorossete formation. Immunohistochemical study revealed positive staining of the tumor cells for S100, neurofilaments, neuron specific enolase, vimentin and myoglobin. Primitive neuroectodermal tumors are rare malignant round cell tumors of the kidney. A correct diagnosis can be made on light microscopic features, and by immunohistochemically positive staining for more than one neural marker. This neoplasm should be differentiated from other renal neoplasms composed of small round cells.

Adult↗
PubMed2002

Colorectal cancers in Saudi Arabia.

OBJECTIVE: The aim of this retrospective study is to delineate the histopathological profile of colorectal cancers seen at King AbdulAziz University Hospital, Jeddah, Kingdom of Saudi Arabia and to compare our findings with 12 other studies published in the literature from other areas of the Kingdom of Saudi Arabia. METHODS: Our study group consisted of 39 colorectal cancer patients, who were examined in the department of Histopathology at King AbdulAziz University Hospital, Jeddah, Kingdom of Saudi Arabia, over a period of 4 years from January 1996 to December 2000. The data was retrieved and analyzed. The histopathological characteristics of the tumor such as tumor differentiation, tumor Duke's staging and grade of all the tumors were studied and compared with age of the patients. RESULTS: We received 2552 gastrointestinal endoscopic specimens during a 4 year period; out of these 276 were colorectal specimens. We found 39 cases (21 males and 17 females) of colorectal cancer during this period, which constituted 1.5% of total endoscopic biopsies and 13.8% of colorectal biopsies. Among these cases there were 31 cases (81%, mean age 56) of colorectal adenocarcinoma, 3 cases (7.6%, mean age 35) of signet cell carcinoma, 2 cases (5%, mean age 55.5) of mucinous adenocarcinoma, one case (2.5%, age 68) of metastatic papillary carcinoma, one case of mixed mucin secreting signet cell carcinoma (2.5%, age 64) and one case (2.5%, age 55) of poorly differentiated squamous cell carcinoma. In our study 21% of patients presented in their 3rd decade of life, 18.4% in the 4th decade, 15.8% in the 5th decade, 26.3% in the 6th decade, 10.5% in the 7th decade and 7.9% in the 8th decade. CONCLUSION: Colorectal carcinoma showed frequent presentation in our population. Some malignant lesions showed early presentation as compared to United States of America, with 6.9% cases presenting at a young age and 23.6% of cases presented at middle age. In order to achieve early diagnosis, a comprehensive cancer education program should be planned and executed, and proper screening programs should be launched.

Adult↗
PubMed2002

Modern aspects of continuous medical education.

Continuous medical education represents the final and often most poorly understood stage of physician education. It is defined as any and all ways by which doctors learn after the formal completion of their training. While evidence-based medicine is defined as "the conscientious, explicit and judicious use of current best evidence in making decisions for the care of individual patients. The practice of evidence-based medicine means integrating individual clinical expertise with the best available external clinical evidence from systematic research." The primary purpose of this article is to discuss the modern and technological aspects of continuing medical education and how it helps to maintain and improve clinical performance of practicing doctors and patient care. The article also emphasizes evidence-based medicine as a newly evolved, rapidly growing discipline for learners and researchers, which has extended the application of its principles to all professions associated with health care, including purchasing and management.

Education, Medical, Continuing↗
PubMed2002

Role of fine needle aspiration in diagnosing breast lesions.

OBJECTIVE: To determine the diagnostic efficacy of breast fine needle aspiration (FNA), using 72 cases that were having both FNA cytology and follow-up histology diagnosis. The study results were compared with results of 27 other studies in the literature. A review of literature regarding the additional benefits of performing "Triple Test" in increasing the cumulative diagnostic accuracy of FNA is also included. METHODS: Our study group consisted of 72 FNA cytologies of female breasts performed at our institution and followed by a histological diagnosis. The following parameters: Sensitivity, specificity, accuracy, predictive values, false positive and negative fraction rates were determined to establish the diagnostic efficacy of the breast FNA. RESULTS: The sensitivity of FNA procedure was 98.4% and specificity 60%, with the predictive value for positive diagnosis 93.9% and for negative diagnosis 85.7%. The overall diagnostic accuracy was 93%. The false positive fraction was 6% and the false negative fraction was 14.2%. The false positive and false negative cases were recorded as having a minimal effect on patient management, as all the false positive and negative diagnosis' were picked up at intra operative frozen sections, and hence no over or under treatment was given to the patients due to these FNA results. CONCLUSION: Fine needle aspiration breast biopsy is an efficient tool and yields a definitive diagnosis, and its use for routine diagnosis must be encouraged since it has high positive (93.9%) and negative (85.7%) predictive values.

Biopsy, Fine-Needle↗
PubMed2002

Experience of liver disease at a University Hospital in Western Saudi Arabia.

OBJECTIVE: The aim of this retrospective study is to review the pattern of hepatic diseases seen in our setting at King Abdul-Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia and to assist us in appreciating the hepatic prototype in our region. METHODS: Our study consisted of 246 consecutive liver biopsies. Lesions were studied considering histological type, age and gender of the patients and anatomic location. Distribution of hepatic lesions were classified into 4 categories as 1. Chronic inflammatory lesions, 2. Cirrhotic lesions, 3. Neoplastic hepatic lesions and 4. Pediatric and hereditary hepatic lesions. RESULTS: Chronic inflammatory lesions comprised of 123 (50%) cases (mean age 38.1), most commonly reported being chronic hepatitis 82 cases (33.3%, mean age 42). Among these patients with chronic hepatitis, 59 cases were positive for hepatitis C virus (HCV), 21 cases were positive for hepatitis B virus (HBV) and 2 cases had both HCV and HBV. Twenty cases were diagnosed with cirrhosis (mean age 38.2). Among these cirrhotic lesions 16 cases were positive for HCV, 4 cases were positive for HBV. Neoplastic lesions were mostly malignant and comprised of 41 (15.5%) cases (mean age 44.7), with only one benign lesion diagnosed as benign hemangioma (age 48 years). Among malignant lesions, the majority were metastatic lesions, 18 were adenocarcinoma metastasis, all with primary from the gastrointestinal tract (mean age 46.6) and 12 with lymphomatous metastasis (mean age 41.2). There were 10 cases of hepatocellular carcinoma (mean age 43). Pediatric hepatic lesions comprised of 35 (14.2%) cases with the most common lesion being extrahepatic bile duct obstruction in 6 cases (mean age 2 months). CONCLUSION: Chronic active hepatitis was the most common inflammatory lesion, metastatic carcinoma was the most common neoplastic lesion and extrahepatic bile duct obstruction was the most common pediatric lesion of the liver.

Adolescent↗
PubMedDate not supplied

Computer skills among medical learners: a survey at King Abdul Aziz University, Jeddah.

BACKGROUND: We conducted a survey at King Abdul Aziz University to assess computer and Internet related activities, needs, and attitudes of our medical students towards computer assisted medical learning. METHODS: A questionnaire containing 16 questions was distributed among medical students. The question form was prepared to assess the computer skills among students and their involvement in computer and Internet assisted medical and clinical learning activities. Each question was followed by a four or five points containing Likert-type multiple choice answer. RESULTS: A total of 303 medical member of the university filled the forms. Among them majorities were medical students constituting 247 (81.5%), 10 (3.3%) were interns, 9 (3%) residents and 36 (11.9%) were senior residents. 55% of the responders were male and 45% were females. The most important points with their brief responses are: Computer skills: 6.3% Not aware; 93.7% Aware. Purpose of using computer: Personal 62.5%; Professional 15%; Academic 21.9%. Software(s) used: MS office 9.4%; MS Office and Internet 31.3%; MS Office, Internet and any medical software 37%; No software 21%. Connecting to Internet or Email: Not at all 18%; Rarely 18%; Once a week 15%; Every alternate day 25%; Daily 12.5%; Multiple times a day 9.4%. Use of Internet for medical learning: Not at all 22%; Very rarely 22%; Some times 41%; Regularly 15%. Computers and Internet can improve studies and professional skills: No not at all 6%; Yes, to some extent 41%; Yes, too much 53%. CONCLUSION: The use of modern computer and Internet technology will result in more effective medical education. Expansion of computer-assisted learning requires careful strategic planning, resource sharing, staff incentives, and active promotion of multidisciplinary working and effective quality control.

Adult↗