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Biomedical subjects

Ido Solt

Publications and source records attributed to Ido Solt.

At least 19 recordsLinked to original sources
PubMed2005

Hypoglycemia during the 100-g oral glucose tolerance test: incidence and perinatal significance.

OBJECTIVE: To estimate and report the incidence and perinatal significance of hypoglycemia during the 100-g oral glucose tolerance test in pregnant women. METHODS: Over a 3-year period, we analyzed the incidence and perinatal outcome of pregnant women who experienced hypoglycemia, defined as a plasma glucose level of 50 mg/dL or less while undergoing the 100-g oral glucose tolerance test. The study group included women who delivered singletons at term. Women who underwent the 100-g oral glucose tolerance test during the same period and had no hypoglycemia served as the control group. RESULTS: A total of 805 women were included in the study, which comprised 51 women (6.3%) who experienced hypoglycemia during the test and 754 women in the control group. Gestational diabetes mellitus was diagnosed in 5/51 (9.8%) women in the study group, compared with 216/754 (28.6%) women in the control group (P < .03), and the neonates born to these women had significantly lower birth weights. CONCLUSION: The incidence of reactive hypoglycemia during the 100-g oral glucose tolerance test in our population is 6.3%. Women who experience hypoglycemia during the test have a significantly lower incidence of gestational diabetes and neonatal birth weights.

Adult↗
PubMed2005

[Spontaneous umbilical cord hematoma].

BACKGROUND: Spontaneous umbilical cord hematoma is rare and might be associated with fetal death. CASE: An emergency cesarean section was performed on a woman during the 41st week of gestation due to fetal distress. A stretched umbilical cord with hematoma was evident. The infant had tachypnea without any other physical or neurological damage. We speculate that traction of the cord led to a tear of an umbilical vessel, cord hematoma, compression of cord vessels and fetal compromise. CONCLUSION: In case of early prenatal diagnosis of spontaneous umbilical hematoma accompanied with signs of fetal distress, labor should be considered.

Adult↗
PubMed2005

[Cystic degeneration of placental subchorionic intervillous thrombi].

This is a case study of a 31 year-old woman who presented for a routine follow-up examination at 33 weeks of gestation. A 9-cm intrauterine membranous cystic structure, floating in the amniotic fluid, with 3 internal round structures attached on a stalk in close proximity to the placental insertion of the umbilical cord was demonstrated in sonography. A color Doppler study of the cyst was normal and also revealed a normal systolic/diastolic flow ratio in the umbilical arteries. The cyst was not reported on extended sonographic scans at 15 weeks and 24 weeks gestation. The patient delivered spontaneously at term giving birth to a 3300 grams healthy newborn. The pathologic diagnosis was cystic degeneration of subchorionic intervillous thrombi.

Adult↗
PubMed2005

[Malformed pygopagus conjoined twins in a spontaneous triplet pregnancy].

This is a case study of malformed conjoined twins in a spontaneous triplet pregnancy. A 20-year-old primigravida spontaneously delivered at 22 weeks gestation a normal 425-gram male newborn followed by a delivery of a 525 grams pygopagus conjoined male twins. One twin had omphalocele, missing ears, cleft palate and dysmorphic figures while the other had imperforated anus and dysmorphic figures. The Apgar scores were 2/0. The placenta was monochorionic/diamniotic with single umbilical artery supplying both conjoined twins. Conjoined twin in a triplet pregnancy may be diagnosed by ultrasound as early as the first trimester. Failure in diagnosis of the condition resulted in early delivery of three premature infants. All three infants died after delivery.

Abnormalities, Multiple↗
PubMed2004

A life-threatening event: uterine cervical arteriovenous malformation.

BACKGROUND: Uterine cervical arteriovenous malformation is a rare cause of vaginal bleeding. CASE: A 32-year-old multigravida presented with severe vaginal bleeding originating in the cervix, which resulted in a hypovolemic shock. Attempts to control the bleeding included hysterectomy, pelvic arterial embolization, and upper vaginectomy. Each proved unsuccessful. Histopathologic examination revealed an arteriovenous malformation. Despite local packing, suturing of the vault area, and brachytherapy to the vaginal vault, bleeding persisted. Treatment with GnRH agonist and tranexamic acid stopped the bleeding. CONCLUSION: Severe vaginal bleeding can be the result of cervical arteriovenous malformation, and GnRH agonist may be used for treatment.

Adult↗
PubMed2004

A 2 hour versus the 3 hour 100 g glucose tolerance test for diagnosing gestational diabetes mellitus.

AIM: To determine how the omission of the third hour glucose measurement of the 100 g oral glucose tolerance test (GTT) affects the diagnosis of gestational diabetes mellitus (GDM). METHODS: Retrospective chart review of 876 women delivered in a tertiary care hospital in Israel during a three-year period, who underwent a 100 g 3 hour oral GTT following an abnormal 50 g glucose screen. GDM was diagnosed according to the "criterion standard" accepted in the Fourth International Workshop Conference on GDM. The results of the 100 g 3 hour oral GTT were then retrospectively re-evaluated by omission of the third hour plasma glucose measurement from the "criterion standard". RESULTS: GDM was diagnosed in 28.4% of the study. patients, while the omission of the third hour glucose measurement resulted in a 26.4% diagnosis of GDM. The perinatal data of the 18-omitted cases suggests that their exclusion from the GDM group would not have altered substantially the perinatal outcome of the study cohort. CONCLUSIONS: A 100 g 2 hour oral GTT is a simple and economic alternative to the 100 g 3 hour oral GTT.

Blood Glucose↗
PubMed2004

[Prenatal imaging of the Meckel-Gruber syndrome].

A 32 years old woman, gravida 2 para 1, presented at 27 + 5 weeks' gestation with a large fetal head for the gestational age, an occipital encephalocele and ventriculomegaly. Both fetal kidneys were large, echogenic and multicystic, but oligohydramnion was not observed. Post-axial polydactyly of the fetal feet was demonstrated. The Meckel-Gruber syndrome was diagnosed, but termination of pregnancy was declined. Three weeks later, the patient spontaneously delivered an 1890 grams live-born female. The newborn died 2 days later in the neonate intensive care unit.

Adult↗
PubMed2004

[Prenatal diagnosis of fetal neoplasms].

A variety of neoplasms can develop in each fetal organ. Most fetal neoplasms can be detected by ultrasonographic examination. Cancer appearing either at birth or within the first month of life occurs in 36.5 per million liveborn infants. The death rate is 6.24-7.6 per million live births. This article briefly reviews the sonographic findings in the most common fetal neoplasms and presents the authors' experience in the prenatal ultrasonographic diagnosis of fetal neoplasms: intracranial fetus-in-fetu, adrenal neuroblastoma and mesoblastic nephroma.

Female↗
PubMed2004

[Is there an association between PUPPP and preeclampsia, abruptio placentae and fetal death?].

This is a case study of a 28-year old woman, gravida 1 para 0, presented at 37+4 weeks gestation due to purpura and fetal death. A 3700 gram dead male fetus without gross malformation was delivered by forceps. Post delivery abruptio placentae, diffuse intravascular coagulation, fulminant preeclampsia and acute renal failure followed. Skin biopsy revealed pruritic urticarial papules and plaques of pregnancy. The patient fully recovered one week postpartum. This case report discusses a possible association between pruritic urticarial papules, plaques of pregnancy and severe preeclampsia with fetal death.

Abruptio Placentae↗
PubMed2003

Delivery following colon interposition.

BACKGROUND: Colon interposition carries a significant complication rate due to attenuated arterial blood supply, because the interposed colon segment depends on a single vascular pedicle. CASES: We report for the first time five vaginal deliveries in two women following the operation, illustrating the dilemmas encountered in choosing the delivery method in these patients. CONCLUSION: We suggest that vaginal delivery following colon interposition is feasible. If cesarean section has to be performed, extra care must be exercised not to damage the vascular pedicle, particularly when there is a need for mobilizing or palpating the posterior aspect of the uterus.

Adult↗
PubMed2002

Over-the-counter oral analgesia for postcesarean pain.

OBJECTIVE: The purpose of this study was to evaluate patient satisfaction for oral analgesia for postcesarean pain management. STUDY DESIGN: A prospective study was conducted on women who underwent cesarean section with regional analgesia. Women were treated with ibuprofen 400 mg in liquid-filled capsules on the first postoperative day by two modes of drug administration: on patient demand (n = 60) and at predetermined regular intervals (n = 54). Pain intensity and satisfaction were self-evaluated by the patients with use of a visual analog scale. RESULTS: Patients in the fixed time interval group had lower pain scores (by 38%-54%, P <.001) compared with the on-demand group. Satisfaction scores in both groups were high but superior in the fixed time interval group (87.5 +/- 18.8, median 94.5, vs 78.6 +/- 21, median 85, P <.001). CONCLUSIONS: Oral, nonnarcotic, postcesarean analgesia provides satisfactory pain relief. Patient satisfaction can be further enhanced by providing the medications in fixed time intervals rather than leaving it to patient request.

Administration, Oral↗
PubMed2002

The effect of meperidine and promethazine on fetal heart rate indices during the active phase of labor.

BACKGROUND: Visual interpretation of fetal heart rare monitoring is subject to intra- and inter-observer variability. OBJECTIVE: To examine the effect of intrapartum administration of meperidine and promethazine on fetal heart activity measured objectively by a computerized system. METHODS: Fourteen healthy women with normal pregnancies at term were studied during the active phase of labor. Fetal heart rate was recorded with the Oxford Sonicaid system 8000. Recordings were performed for 40 minutes prior to and after maternal intravenous administration of meperidine 50 mg with promethazine 25 mg. RESULTS: The combination of meperidine and promethazine caused a significant decrease in the number of accelerations of 10 beats per minute (9.7 versus 2.6, P = 0.002) and 15 beats per minute (5.2 vs. 1.4, P = 0.003), time spent in episodes of high variation (14.8 vs. 2.0, P = 0.005) and short-term variation (7.8 vs. 5.0, P = 0.003). On the other hand there was an increase in the time spent in episodes of low variation (5.3 vs. 19.7, P = 0.009). CONCLUSIONS: Maternal administration of meperidine with promethazine has a significant effect on FHR indices during the active phase of normal labor.

Adjuvants, Anesthesia↗
PubMed2002

[The pine processionary caterpillar Thaumetopoea pityocampa].

The pine processionary caterpillar Thaumetopoea pityocampa (Lepidoptera: Notodontidae) is considered to be a serious pest of medical importance. The hair on the dorsum of the last instar larvae of the moth may cause urticarial reactions (erucism) as well as eye problems and temporary blindness. In Israel, the pest occurs in all pine plantations as well as on ornamental pine trees in urban areas. The biology, ecology and management of the moth population are discussed as well as the mechanism of action of the urticarial hairs and their medical significance. Awareness of the life cycle and ecology of the pest may reduce the contact of the population with the urticarial hairs and prevent the morbidity caused by it.

Animals↗