Biomedical subjects

Ikramullah Khan

Publications and source records attributed to Ikramullah Khan.

3 recordsLinked to original sources

PubMed2003

Mastoiditis in children.

Fifty-two children with mastoiditis were treated at the Federal Government Services Hospital over a period of 15 years (from 1986 to 2000). The salient feature in these cases was the presence of a post-auricular swelling and mastoid abscess. Extensive cholesteatoma was seen in 80.7 per cent of cases and 19.3 per cent had granulations in the mastoid cavity. Significantly, all patients had a history of chronic ear discharge prior to abscess formation. These children belonged to poor communities, were malnourished and attended hospital in a state of emergency. The presentation and course of the disease confirms the aggressive and potentially serious nature of the pathology requiring early medical attention in order to avert impending complications. It appears that in our environment acute mastoiditis with abscess formation develops from chronic otitis media and the cholesteatoma. The surgical procedures conducted in these cases were radical and modified radical mastoidectomy.

Abscess↗

PubMed2002

Middle-ear reconstruction: a review of 150 cases.

This study is based on a retrospective analysis of 150 cases of tympanoplasty and ossicular chain reconstruction as a one-stage procedure. It was conducted at the Federal Government Services Hospital, Islamabad from 1983 to 1999. Temporalis fascia was used for myringoplasty and a sculptured autologous incus to bridge the malleus to stapes head and malleus to footplate gap. These interpositions have produced stable ossicular assemblies and provided satisfactory post-operative hearing gains. One hundred and twenty-six (84 per cent) patients achieved a healed tympanic membrane three months post-operatively. One year post-operatively, 121 (81 per cent) patients had an intact tympanic membrane and at five years 119 (79 per cent) had an intact tympanic membrane. The success rate was based on an intact tympanic membrane and an air-bone gap of less than 30 dB one-year post-operation. Accordingly, the overall success rate was 80 per cent (120 cases). Hearing gains in cases with an absent stapes arch were poorer than in cases with an intact arch. Early (one to three months) post-operative complications included tympanic membrane perforation, lateralization of the graft and persistence of infection. Late (one to five years) complications included the appearance of an anterior perforation and retraction and thinning of the tympanic membrane.

Adolescent↗

PubMedDate not supplied

Application of alvarado scoring system in diagnosis of acute appendicitis.

BACKGROUND: In conditions like acute appendicitis it is impractical to have definitive diagnosis by gold standard test (histopathology) before surgery, we would like a simple test like Alvarado scoring system which depends on the presence and absence of certain variables and which provides an accurate guide to whether or not the patient has the condition. This study was conducted to evaluate Alvarado scoring system for the diagnosis of acute appendicitis in our set up. METHODS: 100 consecutive patients with suspected acute appendicitis admitted in Surgical B unit, Khyber Teaching Hospital Peshawar, during the period from July to December 2003 were included in the study. They were given specific scores according to the variables of Alvarado scoring system and then divided into 3 groups. Group 1 patients (score 7 or more) underwent surgery, group 2 patients (score 5-6) were admitted for observation and group 3 patients (score 4 or less) were discharged home. Patients from group 2 with increased symptom intensity (score 7 or more) in reevaluation underwent surgery. Diagnosis was confirmed by histopathological examination. Reliability of scoring system was assessed by calculating negative appendicectomy rate and positive predictive value. RESULTS: Out of a total 100 patients 64 patients underwent surgery and appendicitis was confirmed in 54 cases, thus giving negative appendicectomy frequency of 15.6% (male 12%, female 17.9%). Perforation rate was 7.8%. Positive predictive value was 84.3% (males 88%, females 82.1%). CONCLUSION: This scoring system is easy, simple and cheap complementary aid for supporting the diagnosis of acute appendicitis especially for junior surgeons.

Adolescent↗