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Imelda G Mediero

Publications and source records attributed to Imelda G Mediero.

5 recordsLinked to original sources

Erythema dyschromicum perstans in children: a report of 14 cases.

BACKGROUND: Erythema dyschromicum perstans (EDP) or ashy dermatosis is a peculiar, slowly progressive, macular hyperpigmentation, which leaves a permanent discoloration. It is an acquired dermatosis that occurs most frequently in Central and South America. EDP usually appears in adults, but some isolated cases and small series have been reported in prepubertal children. METHODS: A retrospective review of cases of EDP in 10-year-old children or younger, attended in a pediatric hospital between 1990 and 2003. RESULTS: We present 14 cases of EDC in children 10 years and younger. With an additional 25 cases reported so far in the English language literature, a total of 39 children have been described. Unlike adult patients, who are most commonly of Hispanic origin, children with EDP are usually Caucasian. Other important facts in children with EDP are the absence of consistent trigger factors and an eventual improvement or resolution of the lesions in 50% of prepubertal patients. CONCLUSION: We suggest that EDP is a distinctive clinical entity, different from lichen planus and lichen planus pigmentosus, which may be identical to the so-called idiopathic eruptive macular pigmentation.

Child↗

Schamberg's purpura in children: a review of 13 cases.

BACKGROUND: Schamberg's purpura (progressive pigmentary dermatosis or pigmented purpuric dermatosis) is uncommonly described in preadolescent children. PATIENTS AND METHODS: A retrospective review of cases of Schamberg's purpura with onset before 10 years of age was undertaken. Clinical and histopathologic data, as well as analytical studies including hemogram, erythrocyte sedimentation rate, serum chemistry, urinalysis, cryoglobulins, and screening for thrombotic and clotting disorders were recorded. RESULTS: A total of 13 patients (3 male and 10 female) from 1 to 9 years of age (median, 5 years) had the typical cutaneous features of Schamberg's purpura. The lower limbs were affected in all patients. Lesions were unilateral in 3 cases. In 4 patients, lesions faded within 1 to 4 years, and in 1 patient lesions improved after 6 years. In 8 patients lesions persisted 1 to 7 years after. Laboratory studies were normal in all patients. CONCLUSION: Schamberg's purpura is a chronic benign form of pigmented purpura which is occasionally seen before puberty.

Child↗

Aleukemic congenital leukemia cutis.

A newborn girl had typical "blueberry muffin" skin lesions, which showed histopathologic features of myelomonocytic leukemia cutis. We could not demonstrate leukemic infiltration of bone marrow in four aspirates. Her course was complicated with primary pulmonary hypertension, which led to death at 7 months of age. We emphasize the persistence of skin lesions in the absence of bone marrow infiltration by leukemia throughout the course of the disease.

Bone Marrow Examination↗

Nevoid hypertrichosis and hypomelanosis.

A girl with multiple lesions of nevoid hypertrichosis and linear hypopigmentation following Blaschko's lines is presented. She had no extracutaneous anomalies. We hypothesize that this unusual coexistence of skin lesions may represent a further example of "twin spotting".

Biopsy, Needle↗