Biomedical subjects

Inger Rudvin

Publications and source records attributed to Inger Rudvin.

3 recordsLinked to original sources

PubMed2005

Flicker VEPs reflecting multiple rod and cone pathways.

In an attempt to determine whether the relative contributions of magno-mediated and parvo-mediated inputs to the cortex are significantly altered in the transition from cone to rod vision, VEPs were recorded at different luminance levels (photopic to scotopic) for 2Hz square-wave, isochromatic flicker. The VEP mass response appears capable of reflecting major parvo-mediated contributions even at luminance levels for which responses from individual cells in the parvocellular pathway are reported to be weak. Our findings suggest that parvo-mediated responses are the dominant source of high-contrast isochromatic flicker VEPs at all light levels.

Adolescent↗

PubMedDate not supplied

Visual evoked potentials for red-green gratings reversing at different temporal frequencies: asymmetries with respect to isoluminance.

Human visual evoked potentials (VEPs) were recorded for abrupt reversals of 2 cycles/deg (c/deg) square-wave gratings combining high red-green contrast with different levels of luminance contrast. Response characteristics--2nd harmonic amplitudes and peak latencies as a function of luminance contrast--were compared for four different reversal rates ranging from 6.25 Hz to 12.5 Hz. At every reversal frequency, the VEP amplitude and latency plots were nonsymmetrical with respect to isoluminance. The amplitude dropped to a minimum within a region of rapid phase change, always at a red-green luminance contrast for which the green color had the higher luminance, at about 40% or 50% Michelson luminance contrast. The rapid phase shift around this contrast suggested a sudden change in the relative impact of VEP generators with different latencies, possibly dominated by parvocellular or magnocellular input. The most prominent VEP waveform through most of the luminance contrast range, P110, is interpreted in terms of a parvo-mediated response that is attenuated with increasing reversal frequency. Contrast-dependent changes in the P110 amplitude appear to be responsible for the VEP asymmetries reported here.

Adult↗

PubMedDate not supplied

Visual evoked potentials for reversals of red-green gratings with different chromatic contrasts: asymmetries with respect to isoluminance.

Human visual evoked potentials (VEPs) were recorded for abrupt 6.25-Hz reversals of 2 c/deg square-wave gratings combining red-green contrast with different levels of luminance contrast. Response characteristics-- amplitudes and peak latencies as a function of luminance contrast--were compared for four different pairs of red-green colors and an isochromatic yellow grating. For each of the red-green color pairs, the plots of VEP amplitudes and latencies were nonsymmetrical with respect to isoluminance. The amplitude dropped to a minimum within a region of rapid phase change, at a different contrast for each color pair but always at a luminance contrast for which the greener color had the higher luminance. When the contrast-response curve for each of the four red-green pairs was modeled by a simple |CL - CM| opponency of L- and M-cone contrast using a fixed CL/CM weighting ratio of about two, there was a close correspondence between the contrast giving a null in the modeled response and that giving a minimum in the VEP amplitude. So for the stimulus parameters applied here, the reversal VEP appeared to be dominated by L/M-opponent response contributions for which the signed CL/CM-cone weighting ratio was close to a value of minus two rather than to a value of minus one, which is characteristic of the psychophysical red-green detection mechanism and representative of CL/CM weighting ratios for precortical cells in the parvocellular pathway.

Adult↗