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Inger Sandvig

Publications and source records attributed to Inger Sandvig.

3 recordsLinked to original sources
PubMed2006

[A ten-year old boy with progressive neurologic outcome].

BACKGROUND: Rasmussen's encephalitis is a rare chronic inflammatory disease with unknown etiology. Patients with this condition have symptoms of intractable partial epilepsy, often with epilepsia partialis continua combined with a progressive hemiparesis. MATERIAL AND METHODS: The history of a Norwegian ten-year old boy with Rasmussen's encephalitis is described. RESULTS AND INTERPRETATION: The patient had clinical symptoms of Rasmussen's encephalitis. He had intractable partial epilepsy including epilepsia partialis continua. Cerebral MRI showed unilateral right-sided cerebral atrophy and foci of increased signal intensity in cortical grey and subcortical white matter. The boy was operated with right-sided hemispherectomy and is postoperatively seizure free. To our knowledge, this is the first published Norwegian child with Rasmussen's encephalitis. The disorder may be underdiagnosed in Norway. It is important to recognise this disease as early as possible.

Brain↗
PubMed2005

[Infantile spasms].

BACKGROUND: Infantile spasms are an epileptic manifestation typical of infancy. The spasms may be associated with a wide spectrum of brain abnormalities and diseases, but coexisting pathology is not always found. Prognosis depends to a substantial extent on the underlying condition. Most of the traditional antiepileptics are not effective. Adrenocorticotropic hormone (ACTH) and more recently vigabatrin are the most common first-line medications. MATERIAL AND METHODS: We have performed a literature search mainly in the PubMed database on the treatment of infantile spasms. The results are discussed in relation to Norwegian practice, for which the Norwegian Paediatric Society's recommendations are the main guidelines. RESULTS/INTERPRETATION: Vigabatrin has emerged as an accepted first-line medication for infantile spasms in Norway and many other countries, although it has not been shown that this therapy in general is as effective as ACTH/steroids. Well-designed treatment studies have been difficult to carry out. Until the final results of such ongoing studies should give different signals, it seems reasonable to continue to give vigabatrin before hormones. Oral steroids can probably be tried before ACTH, although a firm conclusion about this has yet to be drawn.

Adrenocorticotropic Hormone↗