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Biomedical subjects

Iu A Khavkin

Publications and source records attributed to Iu A Khavkin.

At least 19 recordsLinked to original sources
PubMed1998

[Importance of variation criteria in statistical evaluation of the immune status of work crews].

Variation criteria--variation coefficient, Fisher criterion (F-value) and suggested by the authors index of homeostasis--enable to evaluate completely the state of occupational crews and reveal their compensated disadaptation. Administration of adaptogens (such as oxymethacil) is expedient for correction of premorbid conditions in occupational crews. Increased aboriginality and random selection during occupational activities considerably better adaptational characteristics of the occupational crews.

Adaptation, Physiological↗
PubMed1990

[The determination of the content of immunoglobulin isotypes in the tissues in suppurative-destructive diseases].

Low amounts of immunoglobulins of different classes may be measured by the red cell agglutination inhibition test with the red cells conjugated with the respective blood serum IgG and IgM and colostrum IgA isotypes. A feedback between IgM and IgG levels was detected in extracts of the tissues adjacent to the focus of inflammation during the necrotic phase of the process, whereas during the exudative phase the IgG/IgM ratio grows, probably at the expense of the IgM-IgG change over during lymphocyte maturation.

Abscess↗
PubMed1983

[Biological properties of immunochemically pure tetanus antitoxin].

Immunochemically pure tetanus antitoxin obtained from enzyme-treated horse serum is less reactogenic and anaphylactogenic and possesses higher therapeutic properties than antitoxin purified by nonspecific physico-chemical methods and containing ballast antigens. Due to its increased persistence in the recipient's body, the immunochemically pure antitoxin induces passive immunity in considerably lower doses than the preparations purified by the method "Diaferm-3".

Anaphylaxis↗
PubMed1982

[Therapeutic effectiveness of tetanus antitoxins purified by nonspecific and immunochemical methods].

The treatment of experimental tetanus intoxication in 120 rabbits by the intrathecal injection of antitoxins revealed that the therapeutic effect was directly proportional to the dose of antitoxins, expressed in antitoxic units. The maximum effect (the survival rate 78.6%) was obtained by the injection of antitoxins purified on immunoadsorbents and containing no admixtures. The use of such antitoxins ensured the absence of postinjection complications, while commercial antitetanus serum "Diaferm-3" gave only 16.7% survival rate and produced the equal percentage of postinjection complications.

Animals↗