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Biomedical subjects

Iu Belov

Publications and source records attributed to Iu Belov.

16 recordsLinked to original sources
PubMed1982

[Electrophysiologic characteristics of the syndrome of ventricular preexcitation].

In nine patients with syndrome of ventricular over-excitation of intracavitary electrocardiographic investigation was carried out, including recording of Hiss bundle potentials, right and left auricle, programmed, increment and high frequent stimulations. The anatomic characteristic of the additional connection, on the base of the deformation of QRS-complex and the type of the retrograde conduction in case of ventricular stimulation showed that the connection started from the right auricle. In five--it terminates in the left ventricle, and in four--in the right. In the majority of the patients it is with an effective refractory phase under 300 msec., corresponding to the electrophysiological characteristic of a direct connection between auricles and ventricles. The problem of the origination of the phenomenon of circling excitation in the patients with the syndrome of ventricular overexcitation is discussed.

Electrocardiography↗
PubMed1981

[Effect of korvatone on hemodynamics in the acute stage of myocardial infarct].

The pressure in pulmonary and brachial arteries, cardiac output and the period of isovolumetric contraction of left ventricle were measured prior to and by 15, 30 and 60 min post 4 mg corvaton sublingual administration in 20 patients with acute cardiac infarction by the third day after the disease onset (12--with normal diastolic pressure in pulmonary artery--under 1.87 kPa (14 mm Hg)--group I and 8--with elevated pressure--group II). The mean pressure in brachial artery was established to decrease more pronouncedly in group I (from 12.24 +/- 1.79 kPa (91.8 +/- 13.4 mm Hg to 10.45 +/- 1.61 kPa/78.4 +/- 12.1 mm Hg)--p less than 0.002) than in group II (from 11.96 +/- 1.49 kPa (89.11.2 mm Hg) to 11.22 +/- 1.32 kPa (84.2 +/- 9.9 mm Hg)--p less than 0.10). Heart rate was slightly accelerated in group I (from 83.6 +/- 6.21. min1 to 89.8 +/- 20.8.min-1--p less than 0.05) and in group II--an initial tendency to slow down (from 80.7 +/- 20.0.min-1 to 76.7 +/- 20.7.min61 beats, every 15 min, p less than 0.025). The pressure in pulmonary artery was slightly decreased in group I (average pressure--from 1.93 +/- 0.28 kPa (14.5 +/- 2.1 mm Hg) to 1.64 +/- 0.37 kPa (12.3 +/- 2.8 mm Hg, p less than 0.01), the decrease in group II was more manifested [average--from 3.96 +/- 0.61 kPa (29.7 +/- 4.6 mm Hg) to 3.29 +/- 0.77 kPa (24.7 +/- 5.8 mm Hg)--p less than 0.002 and diastolic--from 2.80 +/- 0.53 kPa (21.0 +/- 4.0 mm Hg) to 2.45 +/- 0.69 kPa (18.4 +/- 5.2 mm Hg)--p less than 0.01]. Those changes were accompanied by manifested reduction of cardiac index (from 3.02 +/- 1.06 to 2.47 +/- 0.61 1/min/m2, p less than 0.025), stroke index (from 36.2 +/- 10.4 to 29.1 +/- 6.9 cm3/m2, p less than 0.01) and stroke working index (from 42.1 +/- 14.7 to 29.2 +/- 9.0 g.m/m2, p less than 0.001) in group I, whereas in group II those indices under went no substantial changes (cardiac index--from 1.96 +/- 0.62 to 1.89 +/- 0.53 l/min/m3, stroke index--from 27.6 +/- 9.7 to 27.6 +/- 9.8 cm3/m2 and stroke working index--from 25.3 +/- 10.8 to 24.1 +/- 9.6 g.m/m2, p less than 00,1). The systemic vascular resitence and delta P/delta T of the left ventricle did not change in both groups (p less than 0,01). The changes in the hemodynamics developed gradually and were best manifested by the 60 min, but 50 per cent of the maximum effect was realized as early as the 15th min. Corvaton, was concluded, by the authors, to be useful in the treatment of the originated stasis cardiac insufficiency in those patients.

Antihypertensive Agents↗
PubMed1981

[Recording of the potential of the bundle of His in patients with disordered atrioventricular conduction].

The potentials of His bundle were recorded in 25, out of 105 patients with intracardial electrophysiological examination, carried out. The standard electrocardiographic devices were used, being reconstructed for the purpose. The patients with AV block, stage I and partial AV block, Wenckebach type manifested blocking (slow down) above His bundle. The patients with AV block, Möbitz type II and the patients with chronic AV block manifested blocking both above and beneath His bundle. With auricle stimulation with alternative frequency, latent pathological disorders of auricle-ventricular conduction could be manifested. The method allows the localization of the level of the block, aiding the solution of prognosis problems, further behaviour and eventually the setting of artificial guide of cardiac activity.

Bundle of His↗
PubMed1981

[Assessment of sinus node function using electrophysiological methods].

Intracardial electrophysiological examination was conducted in 50 patients with suspicious or confirmed data about disturbed function of sinus node--namely: short-term auricular stimulation for determination of sinoatrial time (SAT) and long-term auricular stimulation with increasing frequency with analysis of the phenomena in the post-stimulation period--time of sinus node recovery (TSNR), corrected recovery time of sinus node (CRTSN=TSNR minus the basal cycle of auricle before stimulation), emerging of ectopic rhythm leaders and secondary pauses. The following data were obtained in the two groups of patients formed: Group I--26 patients with ECG data about disturbed function of sinus node (periods of sinus bradycardia under 40 beats (minute and/or sinus pauses over 1800 msec): SAT identical to 375 +/- 168; TSNR = 2714 +/- 562; CRTSN = 1684 +/- 347; SAT over 400 msec was found in 8 out of 22 patients; TSNR over 1400 msec in 20 out of 26 patients, CRTSN over 550 msec in 20 out of 26 patients. Ectopic rhythm leader occurred in the poststimulation interval in 5 out of 26 patients and in 4 patients--secondary pauses over 1800 msec were observed; Group II--24 patients, with no data about disturbed function of sinus node (according to the upper criteria): SAT = 254 +/- 91; TSNR +/- 1082 +/- 168; CRTSN = 326 +/- 108; SAT over 400 msec was observed in none of the patients from that group. TSNR over 1400 msec (but under 1700 msec) was found in one patient, CRTSN in the same patient and in the rest of that group was under 550 msec. No ectopic rhythm leaders and secondary pauses over 1200 msec were found in that group of patients during the poststimulation interval. SAT, TSNR and CRTSN were shortened with a statistical significance in both the patient groups after the administration of atropine--I mg intravenously and the reexamination but in 5 patients from group I TSNR, CRTSN were paradoxically lengthened and became pathological. The electrophysiological methods for the studies on sinus node and the electrophysiological parameters, obtained via them, could contribute to the characterization and assessment of the functional potentialities of sinus node as well as to a better understanding of the mechanism of its injury.

Aged↗
PubMed1981

[Diagnostic value of the spatial velocity electrocardiogram in myocardial infarct].

The object of the study were 220 patients with a myocardial infarction, confirmed clinically, enzymatically and electrocardiographically. Seventeen indices were studied, processed via variation analysis with 8 sites of the infarction alterations. The results were compared with those in subjects with intact hearts, examined and described by the authors in another study with the aid of the same devices. The size of the maximum space velocity is most significantly decreased in all myocardial sites. The results, summed up for anterior and posterior-inferior sites are also presented. The sensitivity of some of the indices was determined as well as the correlation dependence with the level of serum creatine-phosphokinase. Highest proved to be the sensitivity of the maximum space velocity (100%), an index correlating with the level of serum creatine-phosphokinase between --0.60 and --0.64. Conclusions were drawn referring to some potentialities for a further application of the method.

Adult↗
PubMed1980

[Electrocardiographic changes and hemodynamic comparisons in arterial hypertension].

The electrocardiographic criteria for left-ventricular loading were studied in patients with non-complicated arterial hypertension and were juxtaposed to the basic hemodynamic indices, determined via radio-isotope method--quantitative radiocardiography. Regular changes in the hemodynamics and electrocardiographic criteria were found, in the initial phases within the limits of the norm, and in the later ones--exceeding it. The method of correlation analysis was applied between the separate hemodynamic indisec and electrocardiographic criteria for left ventricular loading both in the separate subgroups and for the whole group. Correlation dependence with various values and sign were found. Finally, it was concluded that the classic electrocardiographic criteria for left ventricular loading in case of arterial hypertension obtained a new meaning and should be assessed with consideration given to the subjects' age and in a comparison with hemodynamic characteristic.

Adolescent↗
PubMed1980

[Valve prosthesis in cardiac defects: indications and potentials].

Valvular prosthesis made a good reputation in the treatment of acquired and a series of congenital heart diseases. At the Research Institute of Cardiovascular Diseases, 288 subjects were implanted a total of 324 valves from 1965 to 1979. Only from January 1, 1977 to May 1, 1979--132 patients got valvular prostheses, 71 of them with mitral prostheses, 42--with aortic prostheses and 19--with double valvular prostheses,with a total and immediate postoperative lethality of 22.8%. In 18 of the patients valvular prosthetization was accompanied by some other heart interventions--valvular commissurotomy or plastics, plastics of interauricular defect, etc. The potentialities and indications are developed for surgical treatment with valvular prostheses in cases of mitral aortic and tricuspid heart diseases.

Aortic Valve↗
PubMed1978

[Pathologicoanatomic analysis of deaths from acute myocardial infarct with and without arterial hypertension].

Analysis was performed on 220 cases--decreased with acute myocardial infarction, subdivided into two groups--not hypertonics and hypertonics. The average age of the decreased with acute myocardial infarction with arterial hypertension is higher. Substantial differences are absent in the carriers of coronary type, degree of atherosclerotic affection and coronaries myocardiosclerosis and past infarctions, preceding the development of the acute myocardial infarction, being the cause of the death. Coronary thrombosis, mural thrombosis, acute aneurysms, and embolic complications in the systemic and pulmonary circulation proved to be more frequent among hypertonic. Discrepancies are absent as regards the localization of the necrotic zone and involvment of the ventricular muscles. Rupture incidence in both groups is very high and almost the same--over 25 per cent. External ruptures are found to be more frequent, being most often posterior in hypertonics. Parillary ruptures are characteristic for them. No difference is established concerning the exitus. Left ventricle insufficiency ranks first for both groups--over 67 per cent; second to follow are the heart ruptures with tamponade--about 20 per cent; and third--the arterial embolias in systemic circulation--9--10 per cent.

Acute Disease↗
PubMed1978

[Comparison of precordial electrocartography with pathologicoanatomic data on 20 patients with recent myocardial infarct].

In 20 patients with recent myocardial infarction, that died till the 40th day after the onset of the disease, a comparison is made of the data from the pathologoanatomical findings with the indices from the precordial electromapping. The changes in the ST segment of the precordial electromapping correlate, to a significant extent, to the weight of the infarction zone in patients with interior site of the myocardial infarction (sigmaST r = 0.89, p less than or equal to 0.01; nST r = 0.62, p less than or equal to 0.01). The indices from the precordial electromapping characterizing the changes in depolarization, are with a considerable less degree of correlation dependence to the weight of the enfarcted zone in the same patients (nQS r = 0.62, p less than or equal to 0.62, p less than or equal to 0.05; sigmaAR r/0.45, p less than or equal to 0.05). In patients with posterior and/or inferior site of the infarction the correlation dependence to the indices from the precordial electromapping is less manifested.

Adult↗
PubMed1978

[Precordial electrocartography (mapping) in cardiac infarct].

After a detailed literature survey the authors share the results from the precordial electromapping with the registration of 30 points upon the chest in 34 patients with ischemic heart disease (30 with transmural infarction and 4 with intermediary syndrome). The following indices were followed up: sigmaST (the sum of the elevation of ST segment measured at 60 msec of the S deflection recording) and the index nST (the sum of the points with an elevation greater than 0.1 mV/1 mm). Both indices well correlate to the level of blood creatine phosphokinase, determined 24 hours after the examination. Due to the close degree of correlation dependence, the two indices are interchangable for the practice. The precordial electromapping reflects the degree of extent of the "myocardial hypoxia" as well as the degree of the disturbed biological activity of the tissues, affected by the myocardial infarction.

Acute Disease↗