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Iu F Neklasov

Publications and source records attributed to Iu F Neklasov.

At least 19 recordsLinked to original sources
PubMed2001

[Prospects for predicting the life expectancy of patients with chronic obstructive lung disease for refining indicators for lung transplantation].

Success of lung transplantation is largely determined by the patients' timely referral for surgery. However, the determinants of survival in patients with chronic obstructive pulmonary disease (COPD), potential lung recipients are to be established. To reveal the determinants of survival in patients with terminal respiratory failure, the data from a follow-up of 59 patients with COPD who met the generally accepted requirements for the recipients of an isolated lung were analyzed. The analysis of some clinical, functional, hemodynamic parameters established that the level of hypoxemia and the value of pulmonary systolic pressure were of the greatest prognostic value. The values of external respiratory function did not affect the patients' survival. Thus, patients with COPD should undergo lung transplantation if they have a pulmonary systolic pressure of over 50 mm Hg, pO2 of under 60 mm Hg, and no benefits from their conservative therapy.

Humans↗
PubMed1990

[Correlation of arterial pressure in the forearm with blood pressure in the ascending aorta].

Forearm blood pressures obtained by auscultation were compared with the data of pressure recording in the ascending aorta during diagnostic catheterization in 243 patients with coronary heart disease, arterial hypertension and some malformations of the heart. With indirect measurement, systolic blood pressure was shown to be sufficiently reliable and to characterize systolic pressure in the ascending aorta with assurance, the pressure in the aorta being slightly less (some 10%) in approximately half the cases. The regression equation for systolic pressure in the ascending aorta against forearm pressure is as follows: Y = 0.96X - 1. Measurement of diastolic pressure in the ascending aorta yields less accuracy, so it is advisable to use two regression equations: (1) Y = 0.98X - 1 for a diastolic pressure of 80 mm Hg or less and (2) Y = 0.85X + 2 for a pressure of greater than 80 mm Hg. Thus, ascending aorta pressure values required for invasive hemodynamic studies may be satisfactorily calculated from the data of blood pressure auscultative measurement.

Aorta↗
PubMed1989

[Current status of the problem of chronic cor pulmonale].

Studies of great number of patients with chronic nonspecific pulmonary disease suggest that high levels of pulmonary hypertension are only observed in cases of pulmonary-arterial thromboembolism and primary pulmonary hypertension. In other pulmonary diseases, the significance of pulmonary hypertension seems to be overestimated, as blood pressure in the pulmonary circulation network has values, indicative of the absence of gross morphologic changes of the vascular bed of the lungs. The available indirect methods for the diagnosis of pulmonary hypertension in chronic nonspecific pulmonary disease patients with rather small blood pressure in the pulmonary circulation network are shown to be of little value. Large functional reserves of the right cardiac ventricle which make it possible to cope with a sudden pressure overstrain (to say nothing of the slowly augmenting one) are pointed out. It follows therefore that either as yet unknown factors contribute to the pathogenesis of chronic pulmonary heart decompensation, or there is virtually no decompensation, while the demonstrated clinical symptoms of systemic circulatory congestion are of extracardiac origin. Various aspects of the assessment of the role of pulmonary hypertension and clinical symptoms of decompensated pulmonary heart will be discussed in the next communication.

Blood Pressure↗