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Biomedical subjects

Iu G Aliaev

Publications and source records attributed to Iu G Aliaev.

At least 19 recordsLinked to original sources
PubMed2006

[Examination and surgical treatment of patients with combination of solid and liquid lesions of the kidneys].

The experience in examination and surgical treatment of 41 patients with a combination of solid and liquid lesions of the kidneys is analyzed. Complex examination (including USE, CT and MRI) diagnosed a combination of typical tumor and uncomplicated cyst of the kidney in 39 (95.12%) cases. Combination of a solid node and liquid lesion with renal cell carcinoma structure was seen in 2 (4.88%) cases. Surgical policy was individual for each patient. Patients with liquid lesions of a solitary kidney who have undergone earlier nephrectomy for renal tumor should be followed up because of risk of metachronous cancer.

Female↗
PubMed2006

[Transurethral endoscopic surgical procedures on the ureter].

Seven-year experience in examination and treatment of 92 patients with upper urinary tracts disease is analyzed. Potentials of modern endoscopes, technique of ureteroscopy, indications and contraindications for transurethral endo-surgical procedures on the ureter including in anomalies of the kidneys and upper urinary tracts are described. Results of surgeries for tumors, concrements, ureteral strictures and relevant complications are reported.

Endoscopy↗
PubMed2004

[Association of the complex of polymorphic markers of ACE genes, aldosteron synthetase and endothelial synthetase of nitric oxide with progression of chronic glomerulonephritis].

AIM: To study association of the complex of polymorphic markers of ACE genes (ACE complex), aldosteron synthetase gene (CYP11B2) and endothelial synthetase of nitric oxide (NOS3) with onset, course and progression of chronic glomerulonephritis (CGN). MATERIAL AND METHODS: 117 CGN patients were examined. Genetic predisposition to CGN development was studied by comparison of distributions of alleles and genotypes of polymorphic markers of genes ACE, CYP11B2 and NOS3 in CGN patients and controls (n = 80) free of renal diseases and arterial hypertension (AH). The course of CGN was analysed with consideration of the following factors: AH severity, proteinuria persistence, nephritic level for 6 months and longer, immunosuppressive therapy and response to it, therapy with ACE inhibitors and/or blockers of antiotensin II receptors (ARB). CGN progression rate end point was doubling of initial blood creatinine level. RESULTS: Significant differences in the incidence of the above alleles and genotypes in the patients and controls were not found. The patients were divided into two groups: group 1 consisted of 25 patients carrying the combination of alleles D+C+4a, group 2 consisted of the rest 92 patients. The groups did not differ by CGN course parameters, but renal survival was significantly lower in carriers of the allele combination D+C+4a. Cox's mono- and multifactorial regression analysis has shown that carriage of the allele combination D+C+4a is an independent riskfactor of renal survival deterioration. CONCLUSION: No association was detected between polymorphic markers of genes ACE, CYP11B2 and NOS3 and onset of CGN. Carriage of D+C+4a allele combination is an independent factor of risk for fast progression of chronic renal failure.

Adult↗
PubMed2003

[Intrarenal small tumor of the kidney].

From 1992 to 2002 four hundred and thirty-six patients with kidney tumors were treated. Tumor up to 4 cm ("small" tumor of the kidney) was diagnosed in 143 patients. Intrarenal localization of the tumor was in 35 (24.5%) of them. Two groups of patients with intrarenal tumor were are distinguished: tumor is localized intrasinusly whole (18 patients) or closer to fibrous capsule of the kidney (17 patients). In the majority of cases (31 patients) of small intrarenal tumor radical nephrectomy was performed. Four patients with absolute and relative indications to organ-saving surgery underwent nephrotomy and enucleoresection of an intrasinus tumor. Renal-cell cancer was in 3 of these patients, angiomyolipoma--in 1. All 3 patients with renal cancer are alive in follow-up for 7, 2 and 1.5 years.

Angiomyolipoma↗
PubMed2001

[Transurethral electrosurgery in the treatment of benign prostatic hyperplasia].

The article is devoted to topical problem of modern urology, one of the lines of surgical treatment of benign prostatic hyperplasia (BPH)--transurethral electrosurgery. Physical principles which are the basis of transurethral electrosurgical interventions and influence of transurethral electrosurgery on prostatic tissue are described. Methods of necessary preoperative examination of patients with BPH are presented. The most often used transurethral electrosurgical technique for destruction of hyperplastic prostatic tissue is described. The results of 5-year use of combination of transurethral electroresection and electrovaporisation in the treatment of BPH and its complications are presented. Ways of prophylaxis of possible complications are proposed.

Adult↗
PubMed2001

[Differential diagnosis of renal colic].

Potential of modern examinations in differential diagnosis of renal colic and other emergency states is considered. Renal ultrasonography permits in the majority of cases to make diagnosis based on dilatation of caliceal-pelvic system, sometimes with detection of obstruction cause. It is necessary to differentiate parapelvical cysts from dilatation of caliceal-pelvic system, therefore pharmacultrasonic examination of the kidneys with lasix is recommended. Color dopplerography of the urinary bladder with detection of urine ejection from ureters ostia is analogue of conventional invasive diagnostic method--chromocystoscopy. Magnetic-resonance urography is updated non-invasive, non-contrast and non-radiation method of diagnosis of urinary tract dilatation.

Colic↗
PubMed2000

[Transpubic approach in radical prostatectomy].

Surgical interventions in prostate apex and urethral membranous part are difficult because these structures are in the depth of the small pelvis. Transpubic approach permits easy manipulations in this area. There are the following variants of this approach: symphysotomy, pubectomy, resection of superior horizontal rami of pubic bones, resection of inferior horizontal rami of pubic bones, clinoid resection of pubic bones. The simplicity, adequacy and convenience of different surgical manipulations are the advantages of transpubic approach. The clinoid resection of pubic bones is the optimal variant of this approach. In provides an adequate approach to operated organs, the integrity of pelvic ring is saved, as a result of which there are no severe orthopedic disorders in the nearest and remote postoperative periods. For determination of indications to transpubic approach, the comparative study of the transpubic and low-median approaches in radical prostatectomy was carried out in 50 male cadavers according to parameters proposed by Sozon-Yaroshevich in 1954. The type of constitution, height of symphysis, size and shape of the prostate puboprostatic ligaments, adhesion of ligaments to prostate, prostate position against symphysis, size of small pelvis venous vessels were taken into account. It was established that the angle of surgical action in wound in low-medium approach was 35-50 degrees, in transpubic approach--by 25-30 degrees more. Incline angle of surgical manipulation axis, which reflect the correspondence of surgical section to exposed organ's disposition, is very important in case of organ's immobile position. This angle in low-medium approach was 40 +/- 5 degrees, in transpubic--80-90 degrees. Dorsal venous plexus and urethrals membranous part are approachable if the prostate size is small, but if the prostate volume is more than 30 cm3 and symphysis is high (> 7 cm), it is very difficult to manipulate in this zone in low-medium approach. Transpubic approach warrants thorough and careful prostatectomy. Methods leading to disturbance of pelvic ring integrity (symphysotomy, pubectomy) have no advantages. Clinoid resection ensures the optimum view of operative field and satisfy the main requirements of surgical approach.

Humans↗
PubMed1999

[Adrenoblockers in prophylaxis of acute urination retention after surgery].

The results of operations on the organs of the abdominal cavity and the small pelvis in 70 men are analyzed. For evaluation of the condition of the urogenital system and urination parameters preoperatively all patients underwent ultrasound examination of the urine bladder and the prostate with the residual urine evaluation, uroflowmetry. Summary value of the symptoms was evaluated according to international system IPSS and the quality of life was assessed (QOL). 30 patients administered doxazosin according to the scheme: 2 preoperative days 2 mg/day, then 3 days--4 mg/day, and 3 postoperative days--4 mg/day. 5 patients dook tamsulosin 0.4 mg/day for 5 preoperative days and 3 postoperative days. 35 men took placebo, in this group acute anuria in postop period was detected in 4 patients (11.4%). All of them were over 60 years and had benign hyperplasy of the prostate, they initially had disturbances in urination (in average Qmax = 9.7 ml/sec, IPSS = 7, QOL = 3). Ischuria was absent in patients administered alpha 1-adrenoblockers. The authors suggest that probability of the development of acute retention of urine in postoperative period is higher in persons, suffering from benign hyperplasy of the prostate and in those, who have initial disturbances in urination. The use of alpha 1-adrenoblockers preoperatively and in early postoperative period allows minimizing probability of development of ischuria paradoxa in men.

Acute Disease↗
PubMed1997

[Intravenous tumor invasion in renal cancer].

Intravenous tumor invasion occurred in 84 out of 600 patients who had been operated on for carcinoma of the kidney. The inferior vena cava was thrombosed by a tumor in 54 patients. Ultrasonic examination, computed tomography, and venocavography were used in establishing the diagnosis of intravenous invasion. It is stressed that information on the upper border of the thrombus in the inferior vena cava must be obtained before the operation, and that in block on the inferior cavogram transatrial venocavography is absolutely indicated. The presence of absence of growth of intracaval tumor masses into the wall of the inferior vena cava is an important moment determining peculiarities of the operation. In the authors experience such invasion was encountered in 30% of patients. Fifty-two patients had subdiaphragmatic thrombosis of the inferior vena cava and 2 patients had supradiaphragmatic thrombosis. In addition to radical nephrectomy, 28 patients underwent resection of the lateral surface of vena cava inferior, 17--thrombectomy from vena cava inferior, and 8--resection of a segment of this vein. Postoperative lethality was 9.5%, 5-year survival was 40.8%. It was found that venous invasion without growth of the tumor into the fibrous capsule of the kidney and without lymphogenous and distant metastases has no negative effect on the prognosis if the tumor masses had been removed completely from vena cava inferior. The authors believe operations on patients with renal carcinoma and venous tumor invasion in stages T2N0M0, T3N0M0 and T2-3N1-2M0 to be advisable.

Humans↗
PubMed1991

[Results of surgical treatment of cancer of the kidney with high surgical risk under hyperbaric oxygenation].

Refusal of operative intervention because of high operative risk not infrequently deprives the patients of the only chance to prolong survival. Surgical treatment under hyperbaric oxygenation (HBO) creates adequate conditions for such operations as oxygen saturation of the blood and tissues prevented hypoxia developing due to the severe operative trauma and blood loss. Intraoperative and early postoperative hemodynamic and gas exchange parameters become stable. HBO extends indications for operative treatment of renal carcinoma contributing to improvement of treatment results.

Humans↗
PubMed1989

[Background and precancerous processes in renal cell carcinoma].

150 patients dying from renal cell carcinoma are studied in order to reveal the background disease, incidence and character of the nephrosclerosis and the possible morphogenetic link between nephrosclerosis and carcinoma. Renal cell carcinoma is found to develop in 82.7% of cases in the kidneys with signs of nephrosclerosis. The diffuse nephrosclerosis developing in connection with the hypertension disease, atherosclerosis, diabetes mellitus, chronic pyelonephritis, nephrolithiasis is the most important. Proliferation of the canaliculi epithelium with the appearance of undifferentiated cells are regularly found in the nephrosclerotic areas. The disturbance of the epithelium differentiation is followed by the development of dysplasia the phenotypical variants of which are similar to those of renal cell carcinoma. Adenomas are found in 11.3% of cases of renal cell carcinoma which may originate from the adenomas developing against the background of nephrosclerosis.

Adult↗
PubMed1988

[Oncocytoma of the kidneys].

Fourteen cases (4%) of renal oncocytoma have been detected in a retrospective and current analysis of 350 operative observations of renal carcinoma. Clinical and morphologic (macro-, microscopic, electron microscopic, and angiographic) characteristics of this tumor are described, the differential diagnostic criteria of oncocytoma and renal-cell carcinoma are discussed, as is the prognosis of this condition. The authors point to the possibility of oncocytoma growth into the renal capsule, of invasion into the intra- and extratumor veins, of metastases to the lymph nodes. They recommend distinguishing between well- and intermediately differentiated oncocytomas, for this factor determines the course and prognosis of the disease.

Adenoma↗
PubMed1987

[Multilocular cystic nephroma].

The nephroma occurred in a 38-year-old woman, and its sole clinical manifestation was an aching pain in the lumbar region. Angiographic, macroscopic, and light- and electron-microscopic findings are presented. A special feature of the tumor was the presence of secretory granules in its epithelial cells. The possibility of prostaglandin synthesis by the tumor is discussed.

Adult↗
PubMed1986

[Prognostic criteria in renal cell cancer].

Survival of 94 patients with hypernephroma is evaluated kinetically. The following factors were analysed: sex, age, tumour size, tumour invasion in the fibrous renal capsule, venous invasion, morphologic variant of the tumour, differentiation degree, angiographic tumour type. The main factors affecting the prognosis appeared to be tumour invasion in the fibrous renal capsule and the degree of tumour differentiation. Adenocarcinoma has a better prognosis.

Adult↗
PubMed1984

[Clinico-morphological characteristics of renal-cell carcinoma].

One hundred and fifty patients aged 19 to 79 years operated on for renal-cell carcinoma in 1978-1982 were examined. In 46% of the patients tumour was confined to the kidney, in 30%, it grew into the perirenal fat, and in 18.7%, into the renal veins, in 11.3%, there were metastasis to the regional lymph nodes and in 8%, remote metastasis. Morphologically, tumours were verified according to the classification by N. A. Kraevsky et al.: clear-cell carcinoma was diagnosed in 50.7%, granular-cell carcinoma in 12.7%, sarcoma-like carcinoma in 4.7%, adenocarcinoma in 13.3%, mixed-cell carcinoma with signs of different variants in 18.7% of patients. The morphological picture was compared to the angiographic and main clinical data; the frequency of tumour growth into the fibrous capsule of the kidney and vein and the incidence of metastasis were established for various morphological types of tumour. The incidence of these parameters is not similar at different morphological types, thus it is possible to distinguish different clinicomorphological variants of renal-cell carcinoma.

Adenocarcinoma↗