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Biomedical subjects

Iu I Afanas'ev

Publications and source records attributed to Iu I Afanas'ev.

14 recordsLinked to original sources

[Catecholamine metabolism in various compensatory manifestations of epilepsy patients].

The authors studied the catecholamine metabolism with an additional use of the function loadings by insulin and adrenalin in 77 epileptic patients who were ill for a long time and had marked disturbances in mental activity. The study was conducted in dynamics. The authors revealed a considerable activation of catecholamine metabolism in patients with acute psychotic states during dysphoria and in periods close to attacks against the background of typical, for the studied group, depression of the sympathoadrenalin system. The differences in the nature of reaction to the functional loadings, changing in various stages of the disease development and reflecting, to some extent, the compensatory possibilities of organism were registered.

Adult

[Stress-reaction of the cell. Changes in carcinoma RS-1 and Jensen sarcoma cells following administration of retinol acetate, hydrocortisone and proserine].

In the cells of RS-1 carcinoma and those of Iensen's sarcoma it has been stated that acceleration and inhibition of tumor growth induced by nonspecific influence (vitamin A, hydrocortisone, proserin) are accompanied by uniform morphological changes of intracellular structures. Therefore, it is possible to suggest that the changes observed reflect a certain cell adaptation to the altering environmental conditions (cell stress-reaction). The cell stress-reaction is presented morphologically and hence, can by systematized. An attempt of such systematization is suggested.

Adrenocortical Hyperfunction

[Histogenetic principle in estimation of reactive properties of tumors].

The reactive properties of tumors of epithelial origin (carcinoma RS-1) and connective tissue origin (Jensen sarcoma) are not analogous. Vitamin A inhibits the growth of carcinoma RS-1 and does not change the growth parameters of Jensen sarcoma. Hydrocortisone and proserine increase the growth rate of carcinoma RS-1. Hydrocortisone was found to inhibit the growth of Jensen sarcoma.

Animals

[Histophysiology of the thymus gland].

The article comprises a survey of the literature data on histophysiology of the thymus gland and a discussion of results of the authors' own observations of this gland in rats line "Vistar" in normalcy and in the presence in the organism of a transplanted tumour RS-1. Problems associated with histophysiology of the thymus, including such as differentiation of thymocytes, their relationships with the reticuloepithelial cells, the capacity of the latter for secretion, the role of the stratified epithelial bodies, the hematothymus barrier, etc., are discussed.

Animals