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Biomedical subjects

Iu I Malyshev

Publications and source records attributed to Iu I Malyshev.

At least 19 recordsLinked to original sources
PubMed1993

[Spastic torticollis in children (the problems of the clinical picture, treatment and nosological specificity)].

Twenty-two cases with spastic torticollis in children are analyzed. This syndrome was the only suffering in ten children and was a component of generalized forms of deforming muscular dystonia in twelve. In such cases the time course of spastic torticollis clinical picture, possible alteration of tonic and clinical forms, involvement as a rule of hands and shoulders muscles permit regarding this condition as a variant of local deforming muscular dystonia and not an individual hyperkinesis. The efficacy of routine drug therapy administered to these patients directly depended on the form and pattern of spastic torticollis. Positive shifts were observed in 90.9% of patients, in 40.9% a marked positive effect was attained.

Adolescent↗
PubMed1991

[Late results of mitral valve replacement with ball-type and low-profile prostheses].

The discussion covers long-term results of mitral valve replacement with Soviet-made prostheses. Two hundred and sixty-three patients have been under observation, the follow-up periods lasting from six months to five years. A ball-valve prosthesis (MK4-25) was implanted to 125 patients; 138 patients received a low-profile (,) prosthesis. Functional parameters were improved in 86 (69.9 percent) patients with ball-valve implants and in 118 (89 percent) patients with low-profile implants. Ten ball valve implanted patients (8 percent) and 6 (4.3 percent) patients with low-profile prostheses died in the long-term period. The five-year survival of rotation-disc artificial valve recipients was 90 percent, and that of the ball valve-implanted patients, 83 percent.

Adolescent↗
PubMed1991

[Surgical correction of congenital heart defects in infants and young children].

The results of surgical treatment of congenital heart diseases in 595 children under 3 years of age are generalized. There were no fatal outcomes after correction of coarctation of the aorta (9 cases), patent ductus arteriosus (312), pulmonary and aortic stenoses (7). Among 62 patients who underwent removal of an atrial septal defect 3 (4.8%) died. Operations were performed on 140 patients for a ventricular septal defect with high pulmonary hypertension, 31 (22.1%) of them died from various causes. Operations for complicated heart diseases were acts of despair in children whose condition was critical.

Age Factors↗
PubMed1991

[Myoclonus epilepsy in children and adolescents].

Twelve cases of myoclonus epilepsy initiating in childhood and adolescence were studied clinically, electrophysiologically and biochemically. Myoclonic and epileptic syndromes being most pronounced, the clinical pattern presented certain polymorphism: asymmetry, hyperkinesis, myodystonia, epileptic episodes, mental disorders. The electroencephalographic picture of the disease was variable. Hyperexcretion of glycosaminoglycans and changes in their fraction composition with predominant release of heparan sulphate evidenced for deranged metabolism of mucopolysaccharides.

Adolescent↗
PubMed1991

[Freezing an acutely necrotized extremity for the purpose of preparing the patient for amputation].

102 patients of a high operative risk were prepared for amputation of a lower extremity with acute ischemic gangrene by its freezing and tourniquet application. A special portable freezing chamber was used in most cases which could be installed in any surgical hospital. The refrigeration ranged from 18 hours to 14 days. Purposeful intensive treatment of all disorders suffered by the patient was conducted at the same time. In 92 patients the condition improved and the extremity was amputated. As compared to the control group, the postoperative mortality due to refrigeration reduced from 41 to 18.4%. The method was found to be highly effective in cases with gangrene and diabetes mellitus.

Adult↗
PubMed1990

[Pre-amputation freezing of the extremity in acute ischemic gangrene].

When preparing for amputation in 153 patients with acute ischemic gangrene of a lower extremity, the tourniquet-cold isolation was used. In 137 patients, the damaged extremity was freezed by means of a special portable freezing chamber, which can be used in any surgical in-patient department. The duration of cooling ranged from 18 hrs to 14 days. The state improved in 136 patients, the amputation of the extremity was performed in them. The use of freezing of the damaged extremity permitted to reduce the postoperative lethality from 41 to 19.1%. A high effectiveness of the method in gangrene of the extremity against the background of diabetes mellitus was noted.

Adult↗
PubMed1990

[Simultaneous intrathoracic restoration of the coronary and brachiocephalic blood flow].

The treatment of 3 patients with combined occlusive affection of the brachiocephalic and coronary arteries is discussed. A one-stage intrathoracic operation was carried out. Prosthetics of one or two brachiocephalic branches was conducted at first after which a double of triple aortocoronary shunt was formed under conditions of extracorporeal circulation with the use of cardioplegia. The outcome of treatment was favourable. The formation of an aortobifemoral shunt will be undertaken in one of the patients in a short time. Various problems of tactical and surgical character in one-stage correction of the coronary and brachiocephalic blood flow are discussed.

Arteriosclerosis↗
PubMed1989

[Cooling of the extremities in acute ischemic gangrene].

This is a report on 39 patients (from 36 to 84 years of age) with acute ischemic gangrene of the lower limbs and severe concomitant diseases (ischemic heart disease, arterial hypertension, diabetes mellitus, etc.). Cooling of the necrotic limb with the application of a tourniquet and general nonoperative treatment were conducted in preparation for amputation. Cooling was accomplished with dry ice and common ice in 16 patients and with a special refrigerator in 23 patients. Six patients whose condition was very grave died during refrigeration. Amputation of the lower limb was performed in 33 patient, 26 of them tolerated the operation favourably. Wound complications were encountered in 9 patients.

Acute Disease↗
PubMed1988

[Registration of a diagnosis in complications of surgical treatment of diseases of the lungs and heart].

Autopsy findings (160 deceased patients) were assessed clinically and anatomically. Lethal outcomes occurred after surgical treatment of the lungs and heart. Postoperative complications in the absence of a pathological relation to the primary pathology or its adverse effects were considered in diagnosis documents as an equivalent of a nosological unit, i. e. iatrogenic "secondary" diseases. These conditions resulted either from adequate surgical interventions (78.1% of cases) or were attributed to technical and strategical errors (21.9% of cases). Unification of the complications associated with pulmonary and cardiac surgery implies use of the fundamentals of the "secondary" diseases theory and International Classification of Diseases (the 9th revision).

Adult↗
PubMed1985

[Experience with L-DOPA treatment of children with dystonia musculorum deformans and dystonic hyperkineses in infantile cerebral palsy].

Nineteen children with dystonia musculorum deformans and dystonic hyperkineses were treated by L-DOPA. A mild positive effect was obtained in 6 children, a considerable positive effect in 9 children. A more marked positive effect was obtained in children with dystonia musculorum deformans. The results indicate the efficiency of L-DOPA in the treatment of dystonia musculorum deformans and dystonic hyperkineses against the residual organic background. The advisability of 2-3 month long courses of therapy with L-DOPA 2-3 times a year is discussed. Some patients may need a continuous therapy with maintenance doses of the drug.

Adolescent↗