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Iu I Petunin

Publications and source records attributed to Iu I Petunin.

13 recordsLinked to original sources
PubMed1989

[Quantitative characterization of nuclear polymorphism of the epithelial cells in fibroadenomatosis and cancer of the breast].

A method for quantitative analysis of epithelial cell nuclear polymorphism was suggested, viz. identification of general statistical population using Petunin's criterion. This criterion was employed to assess heterogeneity of visible surface of interphase epithelial cell nuclei and to assay nuclear DNA level in fibroadenomatous hyperplasia and cancer of the breast. Heterogeneity index (h), alongside with other parameters, appeared useful for quantitative assessment of the disease: heterogeneity index values ranging 0.1-0.4 point to pronounced heterogeneity of epithelial cell nucleus surface and DNA level, and are suggestive of malignant transformation of tissue, whereas benign proliferation of the epithelium is usually characterized by 0.4 less than h less than or equal to 0.9.

Adenocarcinoma↗
PubMed1978

[Density of receptor neuron nuclear membrane pores during the early ontogenesis of Gallus domesticus L].

In 10, 14, and 18-day-old embryos, as well as in 3, 14 and 30-day-old chickens, neurons of cerebrospinal ganglia have been studied electron microscopically. A method for quantitative evaluation of pores in nuclear envelope by means of estimating pore density index (PDI) has been suggested. By methods of regressive analysis it has been stated that neuronal development and differentiation in the cerebrospinal ganglion at embryonal and early postnatal ontogenesis of Gallus domesticus are accompanied by a regular increase in density of pores per stipulated unit of the nuclear envelope area. During the studied period of the hen ontogenesis, PDI has a characteristic exponential dependance. A suggestion is made to use the index of the pore density as a criterion for estimating functional state of the receptor neuron.

Age Factors↗
PubMed1976

[Mechanisms of oxygen transport across biological membranes].

Using metallic microelectrodes, intracellular measurements were performed of changes in O2 concentration for spherical oocytes of hens by their replacement from normal (PO2=150 torr) to hyperoxic (to 600 torr) conditions, and vice versa. The curves of O2 influx and efflux were recorded in pulse regime of the working electrode polarization. The character of these curves can be expressed by the following equations: m(t)==c==e=y1t+y0 and m (t) =e-y1t+v0+c, where v1 is determined by the coefficient of cell membrane permeability for O2. Valid differences were shown between values of v1 for oxygen influx and efflux which vanish after the action of cyanides. It is suggested that O2 transport into the cell involves a base component which may be physical diffusion, and an additional component which can be depressed by cyanides.

Animals↗