PubMed Health⌕ Search

Biomedical subjects

Iu I Ukhov

Publications and source records attributed to Iu I Ukhov.

At least 19 recordsLinked to original sources
PubMed1999

[Surgical treatment for autoimmune thyroiditis].

The authors present the experience in the treatment of 1379 patients with autoimmune thyroiditis (AIT). 285 from them underwent surgery (20.6%). Conservative treatment with the use of laser therapy is a base in management of AIT (79.4%). Indications for surgical treatment and its scope were determined intraoperatively according to the results of an urgent biopsy of thyroid gland. They are: cancer of thyroid in combination with AIT, high degree of the risk of malignization, large size of the goitre with the symptoms of constringency of surrounding tissues, presence of pseudonodes and ineffectiveness of the conservative treatment and laser therapy. Follow-up data of the patients after surgical treatment for AIT showed that for several years their mode of life was quite favourable.

Adult↗
PubMed1989

[Morphological appearance of cellular immune reaction in the endometrium in spontaneous miscarriage].

Morphometric analysis of lymphocyte, macrophage and polymorphonuclear leukocyte levels in the endometrial stroma was performed in 67 spontaneous and 30 induced abortions during 5-12 weeks of gestation. The results were correlated with the degree of structural maturity of decidual tissue and terminal chorionic villi and showed activation of lymphocyte macrophage reaction mostly pronounced in case of incomplete decidual transformation of endometrial stroma and hypoplastic alterations of chorionic villi. It was concluded that the aforementioned changes were secondary to a decreased function the gravid yellow body and subsequent activation of cell-mediated immune response in the endometrium during spontaneous abortion.

Abortion, Spontaneous↗
PubMed1984

[Importance of a structural and functional analysis of the fallopian epithelium in tubal pregnancy and endometrial adenocarcinoma].

The structural-functional analysis of the uterine tube epithelium is proposed as an additional indirect index of the ovarian hormonal activity. Several standard types of the tubal epithelium are distinguished (proliferative, secretory, gravidal, non-functional, proliferative-hyperplastic) which are characteristic of certain level of various sex hormones in the woman organism. The control data obtained are used for the evaluation of the hormonal background in women with tubal pregnancy and endometrial carcinoma. The signs of ovarian dysfunction were observed in 55.2 and 43.3% of cases respectively and these symptoms were reflected in the pathogenesis and clinical picture of the diseases studied.

Adenocarcinoma↗
PubMed1983

[Hormone-mediated reactions in the endosalpinx epithelium].

The epithelium of normal uterine tubes resected in 38 young women of the child-bearing age during the periods of the maximal physiological fluctuations of the ovarian steroid hormones levels has been studied. The correlative dependence between the morphometrical data and the results of quanitative biochemical analysis of the estrogen excretion has been investigated. The morphometric method reliably reflects the hormone-dependent variabilities of the oviduct epithelium and makes it possible to perform an objective morphological evaluation of the ovarian functional activity. The height and specific density of cells in the epithelial layer, portion of the aciliary cells and nuclear volume of the ciliary cells are the most important for diagnosis as compared to the excretory level of the estrogenic hormones.

Adult↗
PubMed1983

[Morphological manifestations of the functional activity of the menstrual corpus luteum].

A histomorphological investigation of the corpus luteum has been performed in 60 women with an unchanged menstrual cycle. Physiological changes of the corpus luteum are reliably reflected in the karyometry results, in correlation between immature, mature and distrophic luteocytes, their mitotic activity and in total thickness of the parenchymatous layer. The parameters taken into account are united into a total index of the corpus luteum activity, its functional significance is proved when a parallel estimation of microelements content (zinc and copper) is performed in the corpus luteum tissues. The morphometric indices used demonstrate that the menstrual corpus luteum is mainly formed at the expense of a combined hypertrophy of granulous and theca-lutein cells and maturation of the preceding cellular forms. Regressive changes are characterized by a decreasing volume of the nuclei and distrophic changes of luteocytes, which are especially manifested at the end of the menstrual cycle.

Adult↗
PubMed1982

[Characteristics of the microvascular bed of the uterine tubes in women].

A histological investigation of the fallopian tube vascular bed has been performed in women at various phases of the menstrual cycle (28 observation) and at early uterine pregnancy (6 observations). Topographic isolated mechanisms of blood shunting and deposition participating in cyclic changes in the uterine tube functional activity have been revealed. The blood shunting is performed by the occlusive arterioles and arteriolo-venular semi-shunts situating, mainly, in the tubular isthmus. The blood deposition occurs in the infundibular-ampular portion, at the expense of the postcapillary sinus system, convoluted and occlusive venules. The role of hemomicrocirculatory pathways and the lymphatic sinuses of fimbrias to perform physiological "mechanism of the ova acceptance" is also noted.

Adult↗
PubMed1981

[Cyclic changes in the uterine tube epithelium in women].

Morphometric and histochemical investigations have been performed in epithelium of the fallopian tubes in 108 women operated on various gynecological diseases. Among them the following groups have been detected: with a constant menstrual cycle, uterine pregnancy, chronic estrogenia, menopause and a prolonged age menopause. The data obtained demonstrate that the height of the epithelial covering, part the relative amount of the cilial cells and contents of glycogen and lipids in their cytoplasm depend on the character of the ovarian hormonal activity. During the folliculin phase of the menstrual cycle, a certain proliferation of the cilial cells and accumulation of glycogen (in the fimbrial part) and lipids (in the ampullar part) of their cytoplasm is noted. At a chronic estrogenic stimulation, this process can turn into a glandulo-papillary epithelial hyperplasia of the endosalpinx. Administration of yellow body hormones during the lutein phase of the menstrual cycle produces focal desquamation of the cilial epithelium, which acquires a diffuse character in the fallopian tubes of pregnant women and is accompanied with a decreased amount of glycogen in cytoplasm of epitheliocytes and release of lipids into the oviductal lumen.

Adult↗
PubMed1980

[Morphologic manifestations of immune responses in disrupted tubal pregnancy].

An exudative-proliferative reaction, the base of which make lymphocytes, plasmic cells, macrophages, acidophilic and neutrophilic granulocytes, has been revealed in the wall of the uterine tubes of 60 women with a disturbed tubal pregnancy. Cellular composition of the infiltrate depends on time and type of abortion. A suggestion is made on the role of immunopathologic reactions in pathogenesis of some forms of ectopic pregnancy.

Abortion, Spontaneous↗
PubMed1980

[Cyclic changes in mast cell response and capillaries in the wall of the Fallopian tubes of women].

Mast cells reaction in the wall of the normal fallopian tubes has been studied morphometrically in 48 women subjected to the operation for a uterine myoma and ovarian retention cyst. It has been stated that volume and degree of the mast cell degranulation depends on the menstrual cycle phase, age and part of the fallopian tube. The changes of the mast cells reaction correlate with the capillary diameters in the ampulla and the isthmus of the oviduct. Labrocytes participate in regulation of the microcirculatory blood stream of the fallopian tubes.

Adolescent↗
PubMed1979

[Heterogeneity of neurocytes of different brain regions to repeated superhigh-frequency irradiation].

The study was based on the analysis of morphological changes in the brain of 45 rats exposed for 10 days to ultrahigh frequency field of moderate gravity. Detailed studies of the state of the basophilic substance and the volume of the nuclei in the course of the neurocyte swelling were undertaken. The response of the neurocytes of various brain divisions was found to be heterogenous. The most pronounced were dystrophic changes in the sincipital area of the cortex. A lack of correlation between the character of the nuclear swelling and the degree of chromatolysis in the thalamic neurocytes was noted.

Animals↗
PubMed1978

[Characteristics of toxoplasmosis-induced myocarditis in experimental peroral infection].

In oral infection with cysts and oocysts of strain 131 Toxoplasma gondii, specific interstitial productive myocarditis with involvement of the endo- and pericardium developed in albino mice and guinea pigs in the acute stage of the process. Toxoplasmic myocarditis terminated in focal cardiosclerosis. The intensity of cardiac affection was higher in oral infection with toxoplasm oocysts than in infection with cysts than in infection with cysts. Unabating persistence of toxoplasms in the myocardium of the infected animals after subsidence of acute inflammatory phenomena was revealed (cysts in the myocardium).

Administration, Oral↗