Biomedical subjects
Iu L Butov
Publications and source records attributed to Iu L Butov.
[Morphologic data on the immune reaction of malignant tumors of the stomach].
The authors present a morphological investigation of the status of local immunoreactivity in gastric cancer. It was established that the character and degree of severity of the local immune response in cancerous neoplasms of the stomach depends on the histological structure of the tumour and stage of the pathological process and does not depend on the age of the patient.
[Adenosquamous early gastric carcinoma].
A case of early gastric carcinoma with areas of the adenosquamous differentiation is described. The origin of the squamous epithelium in gastric carcinoma is discussed.
[Epithelial dysplasia of the gastric mucosa in infiltrative cancer].
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[Intestinal metaplasia and stomach cancer].
Foci of intestinal metaplasia of gastric mucosa are known to be heterogeneous both morphologically and functionally, and several types of such metaplasia are now recognized. However, different authors use different criteria for their identification and, moreover, evaluate the signs of metaplasia in different ways. Also, the relationship of different types of intestinal metaplasia to one another and to dysplastic changes in the epithelium and to gastric cancer is a matter of controversy. Variants of intestinal metaplasia with sulfomucin secretion are considered as precancerous states that may give rise to gastric cancer of an intestinal type.
[Dysplasia of the gastric mucosal epithelium surrounding a chronic ulcer].
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[Chronic gastritis and cancer of the stomach].
The paper analyses interrelationships between chronic gastritis and carcinoma of the stomach. It has been recognized that various forms of chronic gastritis preceed carcinoma of the stomach. The source of the carcinoma origin is the epithelium of the gastric pit, intestinal and mixed epithelium. The nearest precursors of the carcinoma are foci of dysplasia of the epithelium developing in pits, intestinal cryptae and mixed glands. Proceeding from the regular emergence of the stomach carcinoma against the background of chromic gastritis, features of carcinogenesis in the stomach, and morphogenesis of chronic gastritis, the authors substantiate the pathogenetic connection between chronic gastritis and carcinoma of the stomach. Secondary changes in the gastric system have been found to develop in the III--IV stages of carcinoma. The main morphological features of carcinoma of the stomach of different histogenesis are characterized.
[Chronic hypertrophic glandular gastritis and stomach cancer].
Histotopographic, morphological, and histochemical investigations of the state of the gastral system in 147 cases with gastric cancer of Ist--IVth state, occurrence of which could not be associated with chronic ulcer or polyp, justified the conclusion that in 9 cases (6.2%) extensive erosive, ulcerous-infiltrative and diffuse cancer developed against the background of preceeding hypertrophic glandular gastritis. Moreover, there was a likelihood that in 7 cases (4.6%) hypertrophic glandular gastritis played a role in the onset of gastric cancer. Chronic hypertrophic glandular gastritis should be looked upon as a pretumour disease of the stomach, a precancer condition in the broad sense of the word. The problems of interrelationship between Menetrier's disease and cancer of the stomach in the present article are not considered.
[Age related morphologic changes in the mucous membrane of the stomach].
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[Pathomorphologic changes in the initial stages of cancer of the stomach].
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[On the pathogenesis of anemia in cancer of the stomach].
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