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Biomedical subjects

Iu M Karash

Publications and source records attributed to Iu M Karash.

At least 19 recordsLinked to original sources
PubMed1990

[The diagnostic and prognostic significance of transcutaneous PO2 dynamics during a functional test in "pretoxicosis" and the initial stage of gestosis].

This study has simultaneously examined the kinetics of oxygen metabolism (KOM) and clinical symptoms of "pretoxemia" and edema of pregnancy. It was found out that estimates of KOM obtained before and after the hypoxia test may allow identification of abnormal tissue respiration typifying "pretoxemia", differentiation between "pretoxemia" and early-stage late toxemia (edema of pregnancy), and prediction of the risk and time of late toxemia, and potential of the body to adapt to hypoxia. Evaluation of KOM before and after the hypoxia test may be employed as a test for subclinical late toxemia.

Blood Gas Monitoring, Transcutaneous↗
PubMed1989

[Kinetics of oxygen metabolism in pregnant women with high risk of developing late toxemia during intermittent normobaric hypoxia].

Oxygen metabolism kinetics (OMK) was investigated in 90 pregnant females with high risk for late gestoses and associated vascular disorders (essential hypertension, stage I, and neurocirculatory asthenia of hyper- and hypotonic type) exposed to preventive treatment with intermitting normobaric hypoxia (INH). The study revealed that initial disorders of tissue respiration were featured with compensatory stimulation of tissue oxygen consumption. In early signs of late gestosis the consumption intensity was found to be diminished. During INH treatment course there was an evidence of normalization in oxygen metabolism. The time-course of OMK values permitted to assess the level of systemic adaptation to hypoxia in pregnancy. INH technique was proved to be an efficient nonpharmacological method of late gestosis prevention.

Female↗
PubMed1989

[Preventive use of intermittent normobaric hypoxic hypoxia in pregnant women at high risk of developing late toxicosis].

The authors studied the efficiency of preventive usage of intermittent normobaric hypoxic hypoxia (INHH) in 44 pregnant females at high risk for late gestosis in presence of essential hypertension, stages I-II, and hypertensive type of neurocirculatory asthenia. The authors paid attention to a decrease in the incidence of late gestosis, its severe patterns especially, and perinatal mortality.

Adult↗
PubMed1989

[Changes in the functional status of lymphocytes in patients with chronic salpingo-oophoritis treated by normobaric hypoxia].

Therapeutic exposure to normobaric hypoxia improves both clinical and laboratory parameters in patients with chronic salpingo-oophoritis. The unidirectional trend of change is due to normalization of major systemic functions, including lymphocyte activity, owing to the recovery of lymphocyte metabolism and redistribution of T cell subpopulations towards a greater proportion of T helper cells. Adaptation to a moderate hypoxic stimulus is a promising physiologic method of improving nonspecific systemic reactivity.

Adult↗
PubMed1981

[Biorhythm of oxygen tension in uterine and fetal tissues].

Hypoxic cycles with a two fold reduction in PO2 levels (down to 51.7, 43.9 and 53.4%), the frequency of 0.63 +/- 0.07, 1.47 +/- 0.14, 1.98 +/- 0.3 per minute, and the duration of 45.4 +/ 2.9, 28.4 +/- 2.3 and 19.8 +/- 1.9 sec., respectively, were recorded during the measurement of oxygen content in the uterine tissue of pregnant (3-5 days) and non-pregnant rats, as well as in tissues of 13-14-day-old rat fetuses. The oxygen content remained unchanged throughout the whole experiment (30 min) in the peristaltic intestinal wall. The hypoxic cycles were assessed as a mechanism of rhythmic periodic stimulation of metabolic reactions directed towards not only the increased resistance to hypoxia but also towards non-specific resistance of uterine fetal tissues and female body in and out of pregnancy.

Animals↗