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Biomedical subjects

Iu M Levin

Publications and source records attributed to Iu M Levin.

At least 19 recordsLinked to original sources
PubMed1991

[The control of humoral transport of the eye tissues].

Three series of investigations were carried out in experiments on rabbits with administration under the conjunctiva or by means of electrophoresis of lymphotrophic preparations of different mechanisms of actions with the use of a morphological marker: Gerot's mass and Indian ink jelly with subsequent histological study of the eyeball. Dalargin dilated structured liquorolymphatic drainage ducts of the eye. Terrylythin produced a selective effect on the pigment epithelium of the retina, and mannitol provided penetration of the marker into the retina neurons. Thus, it has been shown that it is possible to control selectively the humoral transport of some tissues of the eye by means of lymphotrophic agents.

Amylases↗
PubMed1990

[Control of lymph-drainage tracts of the eye by the use of dalargin].

The objective was to study dalargin in experiment and its effect on drainage tracts in norm and with experimental hypertension, modulating secondary glaucoma. Investigations have been made on 82 rabbit eyes. The overall results show, that subconjunctival and electrophoretic dalargin injection of (0.1%-0.2-0.5 ml) causes the expansion of anterior and posterior lymph-drainage tracts of the eye and have hypotensive effect for ocular hypertension and secondary glaucoma.

Animals↗
PubMed1986

[Approaches to the control of lymphogenic metastatic spread of tumors].

Lymphopoiesis stimulating drugs were injected into the blood of rabbits bearing Brown-Pearce transplantable tumor. It was found that treatment with mannitol targeted on osmoregulation mechanisms and terrilytin--on blood and lymph coagulation intensified the lymphogenic migration of tumor cells. When used in an experimental series involving endolymphic transplantation of tumor cells, the said drugs promoted tumor cell passage from lymph to blood, which resulted in an increased number of metastasis-bearing animals. It was also found that the promoting effect may be counteracted by preliminary endolymphic injection of a fat-soluble antitumor preparation. Lymphopoiesis and lymph flow stimulation in conjunction with thoracic duct draining may be used for removal of tumor cells from the lymphatics.

Amylases↗
PubMed1980

[Hemo- and lymphosorption in cardiogenic shock (an experimental study)].

The important role of toxemia in the pathogenesis of cadiogenic shock was demonstrated in 38 experiments on dogs. It was found that the blood becomes toxic later than the lymph. Lymphosorption arrests the progress of toxemia but does not relieve it if it has already developed. The hemosorption method produced a good effect. Studies showed, however, that it does nor prevent the arrival of lymph with a high toxin content. The best effect was produced when lympho- and hemosorption were combined under conditions of stimulation of lymph production and lymph drainage.

Animals↗
PubMed1976

[Morphofunctional express-diagnosis of liver conditons].

Methods of simultaneous detection of the vitally-essential indices of the hepatic tissue status by injecting neutral red vital dye into the portal vein are described. The liver tissue morphological status, the hepatic cell absorbing capacity, the blood microcirculatory efficacy and the pH shift were assessed on a histological preparation from the liver slice. The dye was extracted from the other portion of the same liver slice and the total amount of the dye absorbed was estimated.

Animals↗
PubMedDate not supplied

[Effect of peptide immunomodulators on microlymphodynamics].

Study of changes of some microlymphocirculatory parameters on the mesentery of anesthesized female albino rats in application of immunomodulators in 3-4 concentrations showed the following. Lympholin and gordox caused no changes of the studied parameters (tonic activity, rate and amplitude of rhythmic phase activity, rate of lymph flow). With gradual increase of concentration, Tactivin caused a greater constriction of the lymph vessels with a reduction of the amplitude of contractions. The changes of the rate of contractions was dose-dependent with increase of the concentration the proportion of vessels with a diminished rate increased. Myelopid increased the rate of contractions with some increase in the rate of lymph flow. Dose-dependence was not found. Leukopeptide caused narrowing of the vessels with a dose-dependent increase of the lymph flow rate. Lienin only reduced the rate of the lymph flow.

Adjuvants, Immunologic↗