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Biomedical subjects

Iu M Maksimovskiĭ

Publications and source records attributed to Iu M Maksimovskiĭ.

At least 19 recordsLinked to original sources
PubMed2004

[Development and use of periodontal dressing of collagen and Lactobacillus casei 37 cell suspension in combined treatment of periodontal disease of inflammatory origin (a microbiological study)].

Periodontal dressing consisting of collagen and Lactobacillus casei 37 cell suspension (cell concentration 108 cells/ml) was created and used in combined treatment of patients with chronic generalized parodontitis. Efficacy of the developed isolation was explained by a considerable decrease of the number and frequency of isolation of aggressive microbial representatives (pigment synthesizing Bacteroids, Actinomyces and Str. intermedius) in periodontal pockets and also Fungus (Candida albicans). This periodontal dressing provided remission up to 10-12 months.

Chronic Disease↗
PubMed2003

[Results of comparative studies of psychophysiological factors essential for self-evaluation of pain during oral therapeutic interventions].

The efficiency of infiltration, conduction, and intraligamental anesthesia with different anesthetics for oral therapeutic interventions was evaluated in 331 patients without concomitant somatic diseases. The levels of reactivity and personal anxiety, as well as the patient's mood have an essential impact on their own appraisal of the quality of analgesia, which the dentist should bear in mind when planning and carrying out anesthesia. Mean and high levels of anxiety are characterized by decreased subjective confidence in the quality of analgesia and can mislead the dentist, if he/she neglects these characteristics.

Adolescent↗
PubMed2003

[Clinical immunological characteristics of the pathogenesis of catarrhal gingivitis (Communication 1)].

In order to evaluate the relationship between cellular and humoral immunity, washings from the gingival sulcus were analyzed in 15 patients with catarrhal gingivitis and 15 subjects with intact periodontium aged 19-22 years. The results indicate a close relationship between local immunity and humoral and cellular defense factors. It seems that decreased IgA level, complement component, and increased activities of C-reactive protein and antistreptolysin-O are the key factors in the development of chronic gingivitis. Permanent bacterial aggression leads to dysfunction of phagocytic and epithelial cells.

Adult↗
PubMed2003

[Cellular immunity in catarrhal gingivitis. Communication 2].

Immunological parameters of the periodontal peripheral blood were studied in patients aged 18-19 years with catarrhal gingivitis during the remission and exacerbation stages and in subjects with normal periodontium. The immune status was studied by flow laser cytometry using monoclonal antibodies. Opposite changes in the lymphocyte and natural killer subpopulations were detected in periodontal blood of patients with catarrhal gingivitis at the stages of remission and exacerbation.

Adolescent↗
PubMed2003

[Efficacy of treatment of chronic destructive forms of apical periodontitis using oral decontamination antibiotic therapy].

The efficiency of preventive oral antibiotic therapy before the root channel filling was evaluated in 78 patients with granulating and granulomatous chronic periodontitis. Positive clinical changes were observed after lincomycin or rondomycin therapy (p = 0.017). The number of complaints was also less in the latter group (p > 0.05). The incidence of x-ray restoration of periapical foci of bone tissue destruction during 6 and 12 months was significantly higher (p < 0.05 and p < 0.01) after preventive treatment with lincomycin or rondomycin, characterized by potent osteotropic effects (decontamination with rondomycin 81.8%, with lincomycin 70.3% vs. 31.0% without decontamination therapy).

Administration, Oral↗
PubMed2003

[Composition of activated immunocompetent cells of periodontal blood in catarrhal gingivitis (Communication 3)].

Activation composition of lymphocyte population and killer cell phenotype are shifted in patients with catarrhal gingivitis during exacerbation and remission. Our findings indicate high activation of T-cellular immunity and NK cells in patients with exacerbation of catarrhal gingivitis, while remission is characterized by decreased level of activated T cells expressing HLA DR+ molecule on their surface and increased level of killer suppressors expressing IL-2 receptors.

Adolescent↗
PubMed2002

[Antioxidant Mexidol premedication of patients with periodontitis during antihomotoxic therapy].

The tranquilizing effect of antioxidant mexydol on 95 patients with chrconic generalized parodontitis against a background of various somatic diseases was evaluated. The anxiety and the efficiency of premedication were accessed according to Korach's and Spilberger's scales and according to the special psychological questionnaire. The quantitative characteristics of premedication were given baised on the psychological tests results. There was registered a definite improvement of health characteristics and of patient's mood in comparison to the initial input data as well as lower lever of their situational anxiety. This proves the tranquilizing effect of premedication with mexidol (5% amp.). The most evident dynamics of these changes can be observed among patients suffering from high initial anxiety level. The findings of the study are based on more than 2 year old history of treatment of 30 patients with traumel. 21 patients suffering from disfunction of the nervous system were given some comprehensive treatment (traumel locally orally and mexidol in injections). The clinical effect resulted in emotional stabilization of patients and reduced the time needed for their clinical treatment. The medicines were combined. No side effects were observed.

Adolescent↗
PubMed2002

[Instrumental evaluation of sensory thresholds in subjects with different pain sensitivity].

Will the aid of a modified apparatus the authors determined the sensory thresholds of tactile, and pain sensitivity, and the limit of pain tolerance. Subject to measurement were 500 persons. By the nature of the initial high sensitivity (minor thresholds), moderate (medium) and low (major thresholds) ones. The effect of taking by mouth metherasine (0.025) and amidopyrine with analgin (0.25 each) was analyzed in each group. It was ascertained that the mechanism of their action, produced the greatest effect in persons with an initially elevated sensitivity to pain stimulators. Metherasine changed to a greater extent the pain tolerance thresholds, whereas amidopyrin with analgin did the same with the pain thresholds. In individuals with an initially elevated pain sensitivity both the pain threshold and that or the pain tolerance were higher. These date are of importance for rational approach to an individual choice of substances to be prescribed with a different attitude to pain.

Adolescent↗
PubMed2002

[Comparative efficiency of local anesthetics from the group of complex amides during therapeutic stomatological interventions].

The efficiency of infiltration, conduction, and intraligamental anesthesia with different drugs for dental interventions was evaluated in 331 patients without concomitant somatic diseases. The efficiency of local anesthesia depends primarily on the drug; other essential factors are the route of this drug administration and type of intervention in the oral cavity. The most effective of the studied anesthetics was 4% artisane with epinephrine 1:100,000; 3% prolocaine with epinephrine 1:100,000 ranked second. These anesthetics maximally realized their effects at intraligamental injection during the treatment of caries and periodontitis.

Adolescent↗
PubMed2000

[The differential diagnosis of avascular necrosis of the temporomandibular joint in systemic lupus erythematosus].

Eight patients with facial skull abnormalities with systemic lupus erythematosus (SLE) and temporomandibular involvement were examined. In 4 patients mandibular deformation was caused by erosive arthritis and in 4 others by aseptic necrosis of the temporomandibular joint. Clinical and x-ray characteristics, magnetic resonance and computer tomography findings in the two groups are compared. A detailed protocol for differential diagnosis of temporomandibular joint involvement in SLE is developed.

Arthritis↗
PubMed1999

[Aseptic necrosis of the temporomandibular joint in systemic lupus erythematosus].

A total of 285 patients with verified systemic lupus erythematosus (SLE) were examined. They complained of painful temporo-mandibular joint (TMJ) and/or limited mobility of the mandible. Eight patients with chronic arthritis of the TMJ and a shortened (by 3-4 mm) mandibular branch were detected. In 4 female patients aged 25-38 with SLE lasting for about 5.5 years, unilateral signs of myoarticular dysfunction of the TMJ, flattening and decrease of the articular head without erosion and destruction, subcortical round foci with uneven internal contours were found in the central or median part of the head, with the compact bone above the foci thinned and the articular surface flattened; this prompted us to regard these changes as avascular necrosis (AN) of the joint. Shortening of the mandibular branch was caused by deformation of the neck of the articular process and its declination backwards. The detected changes in the TMJ were not accompanied by involvement of other joints. All these 4 patients with SLE and TMJ AN suffered from cerebropathy with epileptic attacks (frequent in 2 patients), Raynaud's syndrome, and bright capillaries of the palms and soles; 2 patients developed clinical picture of the antiphospholipid syndrome. Computer tomography and magnetic resonance findings validating the development of TMJ AN in?

Adult↗