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Biomedical subjects

Iu M Sterniuk

Publications and source records attributed to Iu M Sterniuk.

6 recordsLinked to original sources
PubMed1992

[Hormonal correlations in stomach cancer patients].

The urinary excretion of andro- and glucocorticoidogenesis metabolites was studied in 60 patients with gastric cancer (stages II-III and IV). The androgenous activity showed a significant decrease that was manifested in a reduced excretion of 17-ketosteroids (17-KS) and their androgenicity index (AI). With advance of the disease stage androsterone/ethiocholanolon ratio reduced and became less than 1 in most patients. In patients with stage II-III gastric cancer there occurred a significant increase of the glucocorticoid function of the adrenals and a decrease in patients with stage IV cancer. Comparison with the androgenous activity revealed both an absolute and a relative androgenic insufficiency in patients with gastric cancer. It is suggested that reduced production of androgens effects favourably the catabolic manifestation of the effect of glucocorticoids. Drug-stimulated increase of the production of androgens in the body of patients with gastric cancer is desired.

17-Ketosteroids↗
PubMed1989

[The correction of dyslipidemia in breast cancer patients].

A study is presented of 330 patients with cancer of the breast who received a course of radical and restorative treatment. Studied were the dynamics of changes of the content of cholesterol, triglycerids, beta-lipoproteids, its relation with the functional state of lymphocytes and the possible ways of correction of dyslipidemia. The possibility is analyzed of employing dietotherapy, physical loads, drugs in the complex metabolic rehabilitation. It was established that the effect of this complex of measures allows to achieve a distinct reduction of immunodepression in the group of patients with an excessive body weight as well as in persons of middle and older ages.

Adult↗