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Biomedical subjects

Iu N Levashov

Publications and source records attributed to Iu N Levashov.

At least 19 recordsLinked to original sources

[Thirty-five years' experience of thoracic surgery].

The paper pools the experience gained in the surgical treatment of lung malformations in children and adults, which has been used to develop their current classification. It also presents the outcomes of surgical treatment of acute infectious lung destructions, by taking into account the Marchuk severity index. Modes of surgical treatment of bullous pulmonary emphysema have been provided, which yield minimum postoperative mortality rates (3%). The experience of surgical treatment of 110 patients with cicatrical tracheal stenosis is summarized. The authors also present the results of operations made in 390 patients with Stage III non-small cell carcinoma of the lung, specify indications and procedures for resection of the bifurcation of the trachea when the latter is involved in the tumorous process. They also summarize the experience gained in having performed more than 300 operations in the past 5 years for progressive pulmonary tuberculosis, with 2.7% mortality, and 106 final pneumonectomies for postoperative recurrent pulmonary tuberculosis. The experience with allografting of the trachea (n = 2) and lung (n = 3) is important and little studied in our country.

History, 20th Century↗

[Postvaccinal reactions to the administration of a dried staphylococcal vaccine made from water-soluble antigens].

An unequivocal regularity in local and systemic reactions to multiple (in 5 injections) administration of lyophilized staphylococcal vaccine prepared from water-soluble antigens has been established in patients and in healthy adults: the number and intensity of reaction decreased after each subsequent injection. A similar tendency has been observed in the vaccinees who were examined for their IgE levels. These data are indicative of the desensitizing action of the vaccine.

Adult↗

[Immunostimulant preparation made from the antigens of opportunistic microorganisms in the treatment of inflammatory lung diseases].

The results of the trial of an immunostimulating preparation, consisting of Klebsiella pneumoniae, Proteus, Escherichia coli and Staphylococcus antigenic complexes, on 20 patients with acute pulmonary abscess and bronchiectasis are presented. The preparation was introduced subcutaneously in 5 injections. The preparation was found to have low reactogenicity, and in the course of immunotherapy the manifestations of systemic and local reactions became considerably less pronounced. Immunotherapy produced a good curative effect, objectively manifested by a decrease in coughing and in the amount of sputum gradually changing its character. After the fourth and fifth injections the patients no longer ejected purulent sputum. Fluoroscopic examination revealed a considerable decrease in the size of the pathological focus. The preparation stimulated immunological reactions, and immunization resulted in a considerable increase in the titer of antibodies to all components of the combined preparation, as well as in an increase in the number of functionally active T-lymphocytes, in the blood of the patients.

Adjuvants, Immunologic↗

[Immediate results of segmental pneumonectomy in bronchiectasis].

An analysis of case histories of 225 patients with bronchiectasis subjected to lung resections of various volume has shown high efficiency of isolated and associated resection of the basal pyramid with an intact apical segment. The apical segment remaining intact gives positive effects on the rearrangement of the architectonics of the bronchial tree preventing a considerable displacement of the remaining bronchi. The postoperative period in the patients who had an additional treatment of the wound surface of the sixth segment was more favorable as compared with the patients with open wounds.

Adult↗

[Developmental defects of the lungs and their clinical significance].

On the basis of a complex bronchological examination and treatment of 277 cases of 293 various bronchopulmonary malformations, the differential diagnostic features of the most common lung malformations are listed. These malformations: cystic and ordinary hypoplasia, sequestration, tracheal bronchus etc.-are of a special clinical significance for surgeons. Immediate and late results of surgical treatment of 107 patients (38.8%) were studied. They prove a good effect of early operations on patients suffering from lung malformations, while inoperated patients not infrequently develop various complications, such as pulmonary hypertension, secondary bronchiectasis and so on.

Adolescent↗