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Biomedical subjects

Iu V Isakov

Publications and source records attributed to Iu V Isakov.

At least 19 recordsLinked to original sources
PubMed1990

[Hyperbaric oxygenation in acute compression-dislocation syndrome (experimental-morphological study)].

Acute compression dislocation syndrome was reproduced in rabbits by means of epidural brain compression with a balloon. After elimination of brain compression the main group were treated by HBO whereas the control group did not receive HBO. The use of HBO resulted in a decrease of the lethality in hyperextension manifestations. Using the total water measurement in the brain the main group was discovered to have a decrease of brain edema at different times, associated with compression and eliminated compression thereof. Microscopy revealed a reduction of pericellular, perivascular and subependymal edema as well as of edema of vascular plexus and venous brain plethora under the influence of HBO.

Acute Disease↗
PubMed1989

[Effects of hyperbaric oxygenation in acute compression-dislocation syndrome in experimental animals].

A model of the acute compression dislocation syndrome of grave degree was designed by means of local compression of the parietotemporal area of rabbit brain. A study was made of the effect produced by hyperbaric oxygenation (HBO) on the syndrome after compression elimination. HBO has been noted to decrease the lethality, primarily among animals with the gravest manifestations of the syndrome, to bring about frequent and more full-value recovery of the survived animals, and an insignificant lowering of brain edema.

Acute Disease↗
PubMed1988

[Effect of hyperbaric oxygenation on the dynamics of the alcohol abstinence syndrome].

Hyperbaric oxygenation (HBO) was used in 40 patients with the alcoholic abstinence syndrome (AAS), Stages I and II severity, either as a component of multiple modality (in combination with drugs) or the only treatment. The results of clinico-psychoneurological examination have demonstrated that the use of HBO in the treatment of patients with the AAS significantly accelerates the time of AAS elimination as compared with the control group receiving drug therapy alone. An HBO session markedly reduces psychoneurological and somatovegetative symptomatology which is attended by a reduction in systolic blood pressure and in the heart rate. Analysis of the electrocardiographic findings obtained in patients with alcoholic involvement of the heart at the height of the AAS has shown that HBO helps improve the myocardial status. The best results are achieved in patients with Stage II AAS when HBO therapy (two sessions daily) is started at early stages of the syndrome.

Adult↗
PubMed1987

[Clinical effectiveness of hyperbaric oxygenation in the combined treatment of patients with schizophrenia].

Hyperbaric oxygenation (HBO) was employed in 50 schizophrenic patients showing resistance to the conducted drug therapy. Thirty-two patients had shift-like and 18, sluggish, moderately and slowly progressive forms of schizophrenia. HBO treatment was always combined with psychopharmacotherapy. The results of the study have shown the advisability of inclusion of HBO into the multiple-modality treatment of patients with asthenic and apathetic depressions encountered during a shift-like or sluggish, schizophrenia with hysteric-hypochondriac disturbances and obsessions. The maximum therapeutic effect was observed after 10-12 sessions of HBO.

Combined Modality Therapy↗
PubMed1985

[Effect of hyperbaric oxygenation on the course of experimental brain edema].

The authors studied experimental brain edema and morphological changes in the cerebral tissue in 2 groups of animals: the test group receiving hyperbaric oxygenation (HBO) and the control group. The test animals showed a more favourable course of brain injury. Microscopic examination revealed a lesser degree of brain edema and intensification of reparative processes in the cerebral tissues of animals receiving HBO.

Animals↗
PubMed1979

[Hyperbaric oxygenation in the prevention of wound infection in open injury to the locomotor apparatus].

Hyberbaric oxygenation in altitude chambers OKA-MT was used in the complex of prophylactic measures against wound infection in 91 patients with open traumas of the extremities (fractures, amputations, etc.). The effect of hyperbaric oxygenation on the external respiration was studied by the method of spirography. Tetrapolar rheography was used to follow the central hemodynamics. A number of immune parameteres were also studied. Hyperbaric oxygenation was established to abolish hyperventilation and myocardium hyperdynamia, to accelerate the recovery of the neutrophil phagocytic activity and immunoglobulin level, to contribute to the quicker diminishing of edema in the wound area and healing of the stump and open fracture without suppuration, early formation of dry necrosis with a distinct line of demarcation.

Amputation, Traumatic↗
PubMedDate not supplied

[The effect of hyperbaric oxygenation on the course and outcome of acute dislocation syndrome in uncorrected and corrected experimental compression of the brain].

Acute compression-dislocation syndrome of a severe degree was reproduced in rabbits by dosed compression of the brain with an epidurally situated balloon. Animals of the main group were treated by HBO in persisting compression of the brain (series I) and after its correction (series II). Animals of the control group were not treated. HBO had no influence on mortality in series I, a tendency towards reduction of the animals's survival period under the effect of hyperoxia was noted. In series II HBO led to reduction of mortality among rabbits with the severest manifestations of the syndrome and a more frequent and full recovery of animals who survived.

Acute Disease↗
PubMedDate not supplied

[Therapeutic effect of hyperbaric oxygenation in various manifestations of acute renal-hepatic insufficiency].

The studies of the clinical pattern, chest X-ray films, central hemodynamic parameters, hepatic blood flow and respiratory functions in patients with acute renal-hepatic failure due to various exo- and endotoxemias have shown that hyperbaric oxygenation decreases the degree of first to second stage pulmonary hyperhydration and hepatic encephalopathy. Parallel correction of the cardiac output, recovery of the decreased hepatic blood flow and normalization of respiratory function have been observed.

Acute Disease↗
PubMedDate not supplied

[Effect of hyperbaric oxygenation on total water content of brain tissue in experimental traumatic edema of the brain].

Experiments were conducted on 30 rabbits with dosed injury inflicted on the brain; 15 animals were treated by means of hyperbaric oxygenation (HBO), the other 15 animals were not given treatment. The amount of total water in the brain tissue (separately in the grey and white matter) in various areas was determined by dessicating samples to constant weight. A significant reduction in the amount of tissue water in the brain in its traumatic edema occurred under the effect of HBO; a course of 10 sessions proved to be more effective than a course of 6 sessions.

Animals↗
PubMedDate not supplied

[Hyperbaric oxygenation in ruptured cerebral aneurysms during the postoperative period].

The OKA-MT pressure chamber was used. The course consisted of 6-15 sessions at a pressure of 1.6-2.0 at. abs. Hyperbaric oxygenation (HBO) was included in the complex of therapeutic measures applied in the postoperative period in patients with ruptured aneurysms of the cerebral vessels. From comparison of the course of the disease in 47 patients treated by HBO with that in 30 patients not subjected to HBO (control group) the authors conclude that the inclusion of HBO in the complex of measures applied after operations on the cerebral vessels for ruptured aneurysms has a positive effect on the course of the disease: the grave condition is less prolonged; the duration of the meningeal syndrome, headache, and temperature reaction is shorter by 6 days than in the control group; the number of patients with a good result of treatment increases by 18%; mental disorders in the absence of hematoma of the frontal area are prevented; the frequency of suppurations of the postoperative wound diminishes.

Adolescent↗