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Biomedical subjects

Iu V Isakov

Publications and source records attributed to Iu V Isakov.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

[The effect of hyperbaric oxygenation on the course and outcome of acute dislocation syndrome in uncorrected and corrected experimental compression of the brain].

Acute compression-dislocation syndrome of a severe degree was reproduced in rabbits by dosed compression of the brain with an epidurally situated balloon. Animals of the main group were treated by HBO in persisting compression of the brain (series I) and after its correction (series II). Animals of the control group were not treated. HBO had no influence on mortality in series I, a tendency towards reduction of the animals's survival period under the effect of hyperoxia was noted. In series II HBO led to reduction of mortality among rabbits with the severest manifestations of the syndrome and a more frequent and full recovery of animals who survived.

Acute Disease↗
PubMedDate not supplied

[Therapeutic effect of hyperbaric oxygenation in various manifestations of acute renal-hepatic insufficiency].

The studies of the clinical pattern, chest X-ray films, central hemodynamic parameters, hepatic blood flow and respiratory functions in patients with acute renal-hepatic failure due to various exo- and endotoxemias have shown that hyperbaric oxygenation decreases the degree of first to second stage pulmonary hyperhydration and hepatic encephalopathy. Parallel correction of the cardiac output, recovery of the decreased hepatic blood flow and normalization of respiratory function have been observed.

Acute Disease↗
PubMedDate not supplied

[Effect of hyperbaric oxygenation on total water content of brain tissue in experimental traumatic edema of the brain].

Experiments were conducted on 30 rabbits with dosed injury inflicted on the brain; 15 animals were treated by means of hyperbaric oxygenation (HBO), the other 15 animals were not given treatment. The amount of total water in the brain tissue (separately in the grey and white matter) in various areas was determined by dessicating samples to constant weight. A significant reduction in the amount of tissue water in the brain in its traumatic edema occurred under the effect of HBO; a course of 10 sessions proved to be more effective than a course of 6 sessions.

Animals↗
PubMedDate not supplied

[Hyperbaric oxygenation in ruptured cerebral aneurysms during the postoperative period].

The OKA-MT pressure chamber was used. The course consisted of 6-15 sessions at a pressure of 1.6-2.0 at. abs. Hyperbaric oxygenation (HBO) was included in the complex of therapeutic measures applied in the postoperative period in patients with ruptured aneurysms of the cerebral vessels. From comparison of the course of the disease in 47 patients treated by HBO with that in 30 patients not subjected to HBO (control group) the authors conclude that the inclusion of HBO in the complex of measures applied after operations on the cerebral vessels for ruptured aneurysms has a positive effect on the course of the disease: the grave condition is less prolonged; the duration of the meningeal syndrome, headache, and temperature reaction is shorter by 6 days than in the control group; the number of patients with a good result of treatment increases by 18%; mental disorders in the absence of hematoma of the frontal area are prevented; the frequency of suppurations of the postoperative wound diminishes.

Adolescent↗
PubMedDate not supplied

[Potentials of hyperbaric oxygenation in correcting central respiratory disorders in ischemic stroke].

Changes in central respiratory disorders under the effect of hyperbaric oxygenation (HBO) were studied in 29 patients in the acute stage of ischemic stroke. Spirography, tetrapolar rheography, and examination of the blood gas composition were carried out. Before HBO was begun, various disorders of the respiratory function were found (hyperventilation syndrome, periodical rhythms: Cheyne-Stokes respiration, alternating respiration, etc.). It was revealed that HBO session causes a normalizing effect on the respiratory function in central disorders of respiration: the Cheyne-Stokes rhythm was replaced at the end of the session by wave-like respiration which is biologically more adequate, the regimen of hyperventilation changed to normoventilation, etc. There was parallel improvement in the indices of central hemodynamics and the blood gas composition.

Acute Disease↗