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Biomedical subjects

Iu V Zimin

Publications and source records attributed to Iu V Zimin.

At least 19 recordsLinked to original sources
PubMed1992

[The mechanism of action of chorionic gonadotropin on lactate dehydrogenase activity].

The purpose of this report is to demonstrate that chorionic gonadotropin (CG) interacts nonspecifically with lactate dehydrogenase changing its catalytic activity. The binding in vitro of CG (5 mg/ml) to the enzyme is accompanied by conformational changes of its protein and kinetic characteristics. It may be possible that chorionic gonadotropin exercises a controlling influence on lactate dehydrogenase activity in the cell.

Animals↗
PubMed1990

[Respiratory function in newly developed stenocardia and in long-term course of ischemic heart disease].

External respiration was evaluated in coronary patients with varying duration of the disease. Bronchial obstruction was not a rare finding especially in patients with a long history of angina pectoris. In most of the patients the obstruction was reversible as shown by respiration parameters upon inhalation of broncholytics with various mechanisms of action. Respiratory disorders were not associated with dyspnea, derangement of gaseous exchange and could not be attributed to attendant bronchopulmonary diseases, smoking as such patients had not been entered in the study. A 3-year follow-up was not indicative of spontaneous progression of bronchial obstruction.

Adult↗
PubMed1987

[Prognosis for ischemic heart disease patients with episodes of painless myocardial ischemia alternating with rare attacks of stenocardia. The correlation between ischemia and ventricular extrasystole].

Repeated annual 24-hour Holter's ECG monitoring sessions were used as a basis for 4-year follow-up of 108 male coronary patients with episodes of painless myocardial ischemia in the course of their everyday routines, and 144 control patients showing no signs of transient asymptomatic ischemia at 24-hour Holter's ECG monitoring. Four years of follow-up demonstrated no differences between the two groups, compared with respect to the incidence of myocardial infarction and associated mortality as well as aggravations of coronary heart disease, in terms of clinical pattern of the disease, the incidence of acute coronary episodes and survival rates. There were no sudden deaths in either of the groups. Transient painless myocardial ischemic episodes are shown to carry no additional risk of myocardial infarction and sudden death in elderly coronary patients with occasional anginal attacks.

Aged↗
PubMed1987

[Transitory changes in the ST interval of ischemic heart disease patients with stenocardia during 24-hour ECG monitoring].

Five hundred and seventy coronary patients of both sexes, showing occasional attacks of angina of effort, were subjected to 24-hour ECG monitoring sessions at 1 week intervals during 1 month. Ischemic episodes were detected in 139 (24%) patients. A total of 362 ischemic episodes were already detected at the first ECG monitoring session, the majority of those (97%) being painless. Magnitude and duration of ST depression were similar in the absence of pain and during anginal attacks. Repeated sessions demonstrated considerable spontaneous variability in the frequency of ischemic episodes.

Angina Pectoris↗
PubMed1986

[Effect of hyperbaric oxygenation on the extrasystole in ischemic heart disease patients].

A study of the effect of hyperbaric oxygenation (HBO), applied as single sessions or a treatment course, on cardiac rhythm in 82 coronary patients with chronic extrasystole demonstrated positive therapeutic effect to be achieved after the first 5 or 6 HBO sessions in all patients. Further treatment may provoke an aggravation of arrhythmia in some patients. Positive antiarrhythmic effect of a complete HBO course is doubtful, where ectopic activity is increased following the 7th session. There is a correlation between the results of ECG monitoring from the hyperbaric chamber, from session 7 onwards, and 24-hour ECG recording before and after a HBO course. As shown by 24-hour ECG monitoring, positive effect was obtained in 67% of patients with ventricular extrasystole, the number of ventricular extrasystoles remained basically unchanged after a HBO course in 17%, and ectopic activity increased in 15.4%.

Aged↗