[Endocrine function of the pancreas in patients with organic hyperinsulinism syndrome].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to Iu Z Lifshits.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The performing peculiarities of reconstructive stage of pancreatoduodenal resection after previously conducted palliative operation in 212 patients were analyzed. The drainage operation was previously conducted to 89 of them.
The proposed methods of pancreatointestinal anastomosis construction are: with the artificially formed muscular sphincter, with postponed internal anastomosis construction between pancreatic duct and intestine, the anastomosis on screwable frame-work drain. Indication for the methods application, peculiarities of operative procedure and the results of treatment are adduced.
Explore the source record for details and available documents.
Results of dynamic investigation of beta-endorphins and hormonal state were analysed in 34 patients with pancreonecrosis aged from 23 to 54 years. The dependency of this indexes on the severity of clinical course and presence of complications was determined. The correction ways of injurious action of stress-reaction in pancreonecrosis were proposed.
New principle of choice of the surgical treatment method in patients with necrotic pancreatitis was proposed: different operative procedures don't compete one another but are applied in accordance with the disease stage in dynamics. Such tactics permits to choose an optimal surgical approach in every phase of pathologic process course. From 1989 till 1992 the surgical treatment for necrotic pancreatitis was conducted to 54 patients. Pancreatic resection was done to 14 (25.9%) of patients, 4 of whom died. In necrotic focus delimitation or pancreatic tissue sequestration, observed in terms of more than 2 weeks since the disease beginning, necrectomy was conducted in 40 (74.1%) of patients, 4 of whom died.
The investigation of central haemodynamics indexes dynamics with the use of the developed automatized system in 65 patients with pancreonecrosis was conducted for the aim of disease course prognostication and differentiated prescription of cardiotonics. Three stages of circulatory disorders were established. The possibility of patient's death significantly increases in the presence of prolonged depression of cardiac output when rapid effect of conservative therapy is absent.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Xenotransplantation of the pancreatic islet cells was performed in 8 patients with chronic pancreatitis and concomitant diabetes mellitus, operated on the pancreas. In 2 patients, the rejection of the cells transplanted occurred. The causes of failure and possibilities for improving the technique are analysed.
The reversibility of the changes in the common bile duct after elimination of mechanical obstruction and its adequate drainage in patients with choledocholithiasis was studied. A programmed system of prognostication permitting to choose the optimal type of operative intervention with regard for the sizes of the common bile duct after correction has been developed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The analysis of the 10-year experience with surgical treatment of 719 patients with chronic pancreatitis is presented. Of them in 461, the direct interventions on the pancreas were performed. Drainage operations were performed in 270 patients, the lethality was 3.3%, different modifications of pancreatic resection were used in 191 patients, the lethality was 8.3%. Together with the recognized interventions, the new ones--recanalization of the pancreatic duct with plasty of its wall, recanalization of the pancreatic duct by the small intestinal segment, anatomical resection of the pancreatic head were performed. The main requirements for the performance of pancreatic resection in patients with chronic pancreatitis were defined: resection within the limits of the irreversibly changed area of a gland; choice of a method for stump management with regard to functional state of a gland; restoration of physiologic pathways for passage of the food, bile and pancreatic secret. The surgical principles permitting to improve carbohydrate metabolism in patients after pancreatoduodenal resection have been developed.