Characterisation of the Novel HLA-C*08:296 Allele in Two Members of a Family.
HLA-C*08:296 differs from HLA-C*08:02:01:01 by two nucleotide changes, one in an exon and one in an intron.
Humans↗
Biomedical subjects
Ivan Obukhov
Publications and source records attributed to Ivan Obukhov.
Four New Variants of HLA-C Identified by Next-Generation Sequencing.
Sequences of the novel HLA-C*02:31:02, -C*12:03:95, -C*12:03:96 and -C*17:03:06 alleles identified in Russian individuals.
Humans↗
High-Resolution Sequencing Identifies a Novel HLA-Allele-HLA-DRB1*13:368.
The novel HLA-DRB1*13:368 allele differs from HLA-DRB1*13:01:01:01 by one nucleotide substitution G → T in exon 3.
Humans↗
Comparative HLA Alleles and Haplotypes of Bone Marrow Volunteers Recruiting in the Asian and European Parts of Russia.
HLA typing of 9126 haematopoietic stem cell donors living in the Asian and European parts of Russia and identifying themselves as Russians was performed using NGS technology in 2-field resolution at the HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 loci. The study of donors in the Asian part of Russia disclosed 77 alleles at the HLA-A locus, 111 at the HLA-B locus, 58 at the HLA-C locus, 54 at the HLA-DRB1 locus, and 26 at the HLA-DQB1 locus. Donors of the European part of Russia are characterised by the following allelic diversity: 87 alleles at the HLA-A locus, 136 at the HLA-B locus, 72 at the HLA-C locus, 67 at the HLA-DRB1 locus, and 37 at the HLA-DQB1 locus. The most common five-locus haplotype in both populations is HLA-A*01:01 ~ HLA-C*07:01 ~ HLA-B*08:01 ~ HLA-DRB1*03:01 ~ HLA-DQB1*02:01. Throughout the study, 26 new alleles were revealed.
Humans↗
Next-Generation Sequencing Identifies Seven Novel HLA Class I Alleles.
We identified seven novel HLA class I alleles by NGS.
Humans↗