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Biomedical subjects

J A Bachman

Publications and source records attributed to J A Bachman.

8 recordsLinked to original sources

Dissociation of autonomic and cognitive effects of THC in man.

Intravenous THC, 30--44.8 microgram/kg, was administered to four subjects. Each received THC on four occasions preceded by either i.v. saline, 0.04 mg/kg atropine sulfate, 0.2 mg/kg propranolol, or both drugs together. Heart rates, subjective intoxication and symptom ratings, time productions, and EEG activity were measured. In the absence of autonomic blocking drugs, THC produced characteristic tachycardia, subjective intoxication, and EEG effects. After combined autonomic blockade, THC had no effect on heart rate, while subjective and EEG changes remained as intense. These findings argue against the hypothesis that the subjective and EEG effects of THC are mediated by autonomic receptors or by interoception of peripheral autonomic actions of THC.

Adult

Training and performance of rhesus monkeys as operators in a compensatory manual control system.

Two rhesus monkeys were trained as operators in a compensatory manual control system similar to systems used in human studies. Training procedures used to shape compensatory tracking behavior included a multiple shock-avoidance technique, the gradual introduction of the system input, and sharpening visual stimulus control of tracking behavior. Time-on-target scores for the monkeys were 95% to 98% while responding to three different frequency bandwidths of the system input. As frequency bandwidth increased, no significant increase in error was noted, the monkeys returned the target element to the center target area at increasing rates, and the number of shocks delivered to each subject remained low. Bode plots and stripouts of input, output, and error signals resembled those typically obtained in human studies. Through extrapolations based on nonhuman primate performance, the conclusion was that the task development and training procedures of the present study provided a means for estimating human performance in manual control systems under environmental stress or in hazardous environments.

Animals

Human and nonhuman operators in manual control systems.

The human operator in manual control systems is well known from a control theory point of view. The need for highly specialized data in an area which does not permit using human subjects resulted in the study of rhesus monkeys in manual control systems. The performances of monkey and human operators in a simple compensatory control system were similar.

Animals

Assessment of learning needs of nurse educators: continuing education implications.

Because of current structure, content, and outcomes of master's nursing curricula, administrators responsible for hiring nurse educators often have no choice but to employ clinical experts as teachers. This article reports on the results of an investigation designed to ascertain the self-reported learning needs of nurse educators in a southern state. This investigation confirmed that nurse educators have numerous learning needs specific to fulfillment of the nurse educator role. Findings suggest that learning needs differed according to the educator's level of academic preparation and type of employment setting. The results provide useful insights for individuals planning continuing educational offerings for nurse educators with varied backgrounds.

Education, Nursing, Continuing