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Biomedical subjects

J A Borrello

Publications and source records attributed to J A Borrello.

21 records · Page 2Linked to original sources

Hepatic T2-weighted MRI: a prospective comparison of sequences, including breath-hold, half-Fourier turbo spin echo (HASTE).

The purpose of this study was to quantitatively compare the hepatic contrast characteristics of conventional spin-echo (CSE) and fast spin-echo (FSE) sequences with breath-hold T2-weighted images acquired with half-Fourier turbo spin echo (HASTE). Forty-five patients were examined with a phased-array surface coil. Nineteen patients had focal hepatic lesions, including eight malignant tumors, 10 cavernous hemangiomas, and one hepatic adenoma. Twenty-six patients had no focal hepatic lesions. T2-weighted images with comparable TE were acquired with CSE, FSE, and HASTE pulse sequences. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) for liver, spleen, and lesions were measured. FSE demonstrated significantly better quantitative performance than CSE for liver-spleen CNR (P .0084). No statistically significant difference was demonstrated between FSE and CSE for liver or spleen SNR. FSE demonstrated clear scan time and resolution advantages over CSE. HASTE performed significantly poorer than CSE and FSE for liver-spleen CNR (P < .0001), liver SNR (P = .0002 for CSE and P < .0001 for FSE), and spleen SNR (P < .0001). Optimized FSE images with a short echo train length performed comparably to CSE images of equivalent TE. Liver-lesion CNR was suppressed on HASTE images, suggesting that long echo train length FSE sequences could diminish solid lesion detection compared to CSE and short echo train length FSE.

Adenoma, Liver Cell↗

Comparison of MR relaxation times and X-ray attenuation coefficients of focal brain lesions.

Twenty cases of selected focal brain parenchymal lesions that were seen on both X-ray CT and magnetic resonance (MR) imaging were studied retrospectively. The CT attenuation coefficients and MR relaxation times were calculated for each lesion in an attempt to determine if an interdependence existed between these parameters. The CT attenuation and spin-lattice relaxation time (T1) appeared to be independent. There appeared to be an inverse relationship between CT attenuation and spin-spin relaxation time (T2). It is suggested that the explanation of this relationship is that lesions with greater amounts of edema tend to have lower CT attenuations and longer T2s and that this effect plays a major role in determining these values. The reason that T1 does not show a similar relationship is unknown. It is suggested that the explanation may be a combination of more complex factors determining T1 and of small sample size.

Adolescent↗

MR appearance of umbilical endometriosis.

OBJECTIVE: We describe the MR appearance of endometriosis involving the umbilicus in two patients. One patient had a history of laparoscopy performed through the umbilicus; the other had an umbilical hernia. MATERIALS AND METHODS: MR imaging was performed using both a body coil and a spine coil (with the patient lying prone on the spine coil). The lesions were surgically removed and their MR appearance was correlated with the results of histologic analysis. RESULTS: The lesions were well delineated on MRI and showed evidence of prior hemorrhage consistent with endometriosis. Both lesions were shown to be endometriosis at surgical pathology. CONCLUSION: MR imaging was useful for delineating the size and location of the lesions and excluding intraabdominal extension.

Adult↗