Biomedical subjects

J A Brandariz Castelo

Publications and source records attributed to J A Brandariz Castelo.

5 recordsLinked to original sources

PubMed1998

Primary lingual abscess presenting as acute swelling of the tongue obstructing the upper airway: diagnosis with MR.

We report the sudden development of an inflammatory process thought to be of the floor of the mouth with subsequent involvement of the respiratory airway. MR imaging showed an enhancing posterior lingual lesion, consistent with an abscess. Immediate surgical drainage relieved the symptoms. MR imaging allowed accurate diagnosis, which was essential for surgical planning in a condition that was otherwise difficult to diagnose.

Abscess↗

PubMed1995

[Adjuvant chemotherapy in the treatment of pharyngolaryngeal cancers in advanced stages].

Since 1980 we use adjuvant chemotherapy in advanced laryngopharyngeal carcinomas. These cases were resectable and unresectable lesions with tumoral extent to the pharynx as a common characteristic. We analyze the survival of the first 50 cases treated with chemotherapy followed by: A) surgery and radiotherapy (36 cases) and B) radiotherapy alone (14 cases). Results of this not randomized study are compared with a historic group of advanced laryngopharyngeal carcinomas (T4/N+) treated with conventional therapy (surgery +/- radiotherapy). Response to chemotherapy was complete or partial (> 50% reduction) in 56 percent of the patients. There was improvement in overall survival and five-years disease-free survival in the latter group compared with those who did show any response (p < 0.01). We would point out that disease-free survival of the group A was better than historic group (60% vs 36%, p < 0.05), although these result should be carefully interpreted. Laryngeal preservation was achieved in 47 percent in the group A by modification of the initially scheduled radical surgery, in selected cases.

Carcinoma↗

PubMedDate not supplied

[Subdural empyema induced by frontal sinusitis].

Nowadays the complications arising from sinusitis are rare. However its seriousness can even cause death. Intracranial complications are much more uncommon than the orbital ones. However, slight symptoms can appear, which may disjunct the correlation between clinical-radiology and the severity of the infection. The diagnosis is fundamentally based on the TAC, and early treatment with intravenous anti-biotherapy should be implemented, being followed by drainage surgery of the sinus and empyema. We have presented a case which evolved favourably and revised all the literature pertaining to it.

Adolescent↗

PubMedDate not supplied

[Orbital cellulitis and permanent amaurosis: clinical case].

Orbital cellulitis is a rare, potentially serious but complication of acute sinusitis. It is more frequent and benign in children, but in adults usually requieres surgical drainage of the affected sinus. We report a case of aggressive evolution with permanent blindness in an adult without general or local risk factors, in spite of adequate treatment. The literature is reviewed.

Acute Disease↗

PubMedDate not supplied

[Second primary tumors in patients with pharyngo-laryngeal carcinoma].

The risk of second primary tumors of the respiratory and upper digestive tract developing in patients treated for head and neck cancer is well known. In these cases, the entire mucous membrane surface of the tract is affected and predisposed to metachronous or synchronous neoplasms. The mucosa of these patients is extremely susceptible to external carcinogenic stimuli. We report the results obtained in 83 patients with cancer of the oral cavity, pharynx, or larynx who experienced at least one second primary tumor. The most common site of the second primary was the lung (43.2%). We reviewed tobacco and alcohol use, treatments, and survival.

Adult↗