PubMed Health⌕ Search

Biomedical subjects

J A Caldeira

Publications and source records attributed to J A Caldeira.

At least 19 recordsLinked to original sources
PubMed2000

Vertical transposition of the horizontal rectus muscles for congenital/early onset "acquired" double elevator palsy: a retrospective long term study of 10 consecutive patients.

BACKGROUND: Double elevator palsy (DEP) is a not uncommon congenital or acquired clinical entity. Although a full tendon transposition of the horizontal rectus muscles is the widely accepted treatment, the number of reports in the literature is not great, and the techniques used are varied. This study reports on patients with congenital or early onset "acquired" DEP submitted only to a transposition of the horizontal rectus muscles according to Knapp, to add our experience to the literature. SUBJECTS AND METHODS: Ten consecutive patients without complicating factors had the horizontal rectus muscles transposed to the angle of the insertion of the superior rectus. Patient ages ranged from 10 months to 7 years 4 months. The vertical deviation in primary position ranged for distance from 14 PD to 50 PD (mean 30.6 PD) and at near from 12 PD to 50 PD (mean 27.4 PD). Five patients had only a vertical deviation, and five also a horizontal deviation. The first postsurgical evaluation was done between 7 and 39 days (mean 14.3) and the last between one and 196 months (mean 102.1). The fusional status was assessed using the Worth Four-Dot Test and Major Amblyoscope. RESULTS: Postoperatively, 3/10 patients had no vertical deviation for distance. Two were undercorrected (by 1 PD, 8 PD); and five were overcorrected (3 PD, 4 PD, 10 PD and two by 25 PD). The mean correction for distance was 36. 4 PD. Three of the ten patients had no vertical deviation at near; two were undercorrected (by 1 PD, 8 PD); and five overcorrected (two by 4 PD, one each by 6 PD, 7 PD, and 9 PD). The mean correction at near was 29.5 PD. Long term followup changes: The correction for distance between the first and last postsurgical evaluation increased (the preop' deviation decreased) in 8/10 patients (range 3 PD to 45 PD, mean 18.6 PD). At near, 9/10 patients had an increase in the correction of the vertical deviation over this period (range 4 PD to 24 PD, mean 13.8 PD). CONCLUSION: This transposition procedure can reduce or eliminate the vertical deviation both for distance and at near, and has an increased effect over time.

Blepharoptosis↗
PubMed2000

Abnormal head posture: an ophthalmological approach.

BACKGROUND: An abnormal head posture (AHP) is an important clinical sign; it may be due to non-ocular or ocular causes. The literature on the subject is disperse, however. OBJECTIVE: To present a comprehensive discussion on the subject. CLINICAL CONDITIONS: AHP due to an ocular cause can be observed in conditions both not related or related to the extraocular motility. In the latter group, comitant deviations, incomitant deviations, supranuclear palsies, A and V pattern, nystagmus, and central nervous system disorders are included. Facial asymmetry can be a feature of a long-standing congenital or acquired AHP.

Head Movements↗
PubMed1991

Quantification of ocular inflammation with technetium-99m glucoheptonate.

Histological and morphometric evaluation of ocular inflammation is difficult, particularly when there is extensive ocular involvement with abscess formation and necrosis. A quantitative imaging procedure applicable to humans would be important clinically. To establish such a procedure, turpentine-induced ocular inflammation was obtained by subconjunctival injection in the right eye of 55 rabbits. The left eye was used as control and injected with a volume of saline equal to the volume of turpentine in the right eye. Volumes of turpentine or saline were 0.02, 0.04, 0.06, 0.2 and 0.6 ml, and the rabbits were divided into groups 1-5, according to these volumes. Imaging was performed 48 h after turpentine injection and 6 h after intravenous injection of 10 mCi of technetium-99m glucoheptonate (99mTc-GH). An inflammatory reaction index (IRI), defined as the ratio of counts of the right eye divided by counts of the left eye, was used. IRIs were proportional to the degree of inflammation and allowed the distinction of 3 subgroups: one represented by group 4, one by group 5 and one by groups 1, 2 and 3. This method of quantification of ocular inflammatory processes using 99mTc-GH is original, rapid, non-invasive, reproducible and safe, although unable to differentiate inflammatory processes caused by doses of turpentine which are very small and close to each other. It is conceivable that its application to humans will bring new insight into the ocular inflammatory process and response to therapy.

Animals↗
PubMed1982

Tear calcium levels in normal subjects.

Tear calcium contents were measured in 30 normal subjects divided into six groups of 5 individuals each, age ranging from the second to the seventh decade. No significant difference was found among the age groups. A mean of 4.40 mg of calcium/100 ml was determined for the 30 subjects with a standard deviation of 1.22 and a range 2.60-7.60 mg/100 ml. The tear calcium as percentage of the serum calcium was similar in the six groups and a mean of 45.68 was found for the 30 subjects. This figure is quite similar to that of serum ionised calcium as percentage of the total serum calcium values obtained by different authors.

Adolescent↗