Biomedical subjects
Publications and source records attributed to J A Eaton.
A paraformaldehyde perfusion technique is useful in studying biogenic amine-containing cells in the avian lung. In comparison to the frequently used lyophilization technique, the time required to prepare the tissue is greatly reduced.
Formaldehyde induced fluorescence was used to identify biogenic amine-containing cells in the adult chicken lung. Such cells, found in the parabronchial region, are sparsely distributed. There are at least two types of biogenic amine-containing cells in the lung: one type probably contains serotonin and the other a catecholamine. These cells might function as either a humoral or hormonal regulator of pulmonary ventilation and perfusion or as a receptor involved in control of breathing.
Two distinct populations of fluorogenic amine-containing cells were observed in the lungs of nine-week old mice: one with an intense yellow emission, which possible indicates the presence of serotonin; and one emitting a yellow-green fluorescence, which probably indicates the presence of a catecholamine such as dopamine or norepinephrine. Simultaneous identification of two different fluorogenic amine-containing cells, without pre-administration of a precursor to that amine, has not previously been reported. Such evidence of amine-containing cells demonstrated the success of the perfusion-freezing technique and established that cellular storage of fluorogenic amines does occur in vivo under normal physiological conditions. The function of such amine-containing cells has not been established; however, their location and the known physiological effects of amines would suggest regional control of ventilation/perfusion of the lung.
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Osteopathic physicians are licensed physicians practicing in all 50 states. This article describes the philosophy of Osteopathic Medicine and reviews the objective support for it. Special emphasis is placed on somatic, visceral, and psychologic interaction. Specific examples of Osteopathic Manipulative Therapy (OMT) are also described.
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