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J A Estrada

Publications and source records attributed to J A Estrada.

9 recordsLinked to original sources
PubMed1993

Comparative study of the activity and lingering effect of topical antifungals.

We present a combined method of culturing pathogenic dermatophytes and yeasts on human stratum corneum. Topical marketed antifungals are applied in vivo, and the stratum corneum is removed by cyanoacrylate skin surface strippings. After inoculation of the test organism, the extent of fungal growth is measured, indicating by comparison with controls the level of inhibitory effect of the antifungal. Other samples of stratum corneum collected at different time intervals after the arrest of antimicrobial treatment are used to evaluate the lingering effect of the drug. The combination of the data gained by these approaches close to the in vivo situation is used to introduce a classification of antifungals.

Administration, Topical↗
PubMed1992

Dermatopathological aspects of restrictive dermopathy.

We present an immunopathological and electronmicroscopic study of the skin of two newborns affected by restrictive dermopathy. Evidence of abnormal maturation was found in the epidermis, cutaneous appendages, dermis, and hypodermis. Our observations confirm two previous descriptions. We emphasize some unreported data concerning the L1 antigen and Factor XIIIa in the skin. The L1 antigen is expressed in the interadnexal epidermis, but not in hair follicles. This is the reverse pattern compared with normal skin. Factor XIIIa is poorly expressed in dermal dendrocytes, which appear rare compared with controls. The multiple defects in maturation found in all cutaneous tissues suggest a qualitative or quantitative aberration in control mechanisms of tissue interactions.

Antigens, Surface↗
PubMed1991

Cutaneous hamartoma with pagetoid cells.

We report an unusual cutaneous hamartoma with pagetoid cells characterized by the presence of intraepidermal cells resembling Toker's cells of the nipple. These cells were EMA positive and could be related to the histogenesis of some Paget's disease.

Adult↗
PubMed1991

Dendrocytoclasis in Henoch-Schönlein purpura.

We studied by immunohistochemistry the fate of factor XIIIa-positive dermal dendrocytes in Henoch-Schönlein purpura. We have observed apoptosis affecting most of the perivascular dendrocytes. Such an aspect of dendrocytoclasis has never previously been reported in inflammatory disorders in the absence of vasculitis.

Child↗
PubMed1990

Cutaneous presentation of the cardio-facio-cutaneous syndrome.

We present the clinical and histologic features of the cutaneous lesions in a girl with cardio-facio-cutaneous syndrome. Marked tortuosity with hyperkeratosis of the sweat ducts and dystrophy of the hair shafts appear to be the cutaneous hallmarks of this syndrome.

Body Height↗
PubMed1990

Cutaneous mixed infections in AIDS.

We report a new case of mixed infection occurring at the same site of the skin in a human immune deficiency virus-positive patient. Hyperkeratotic and crusted erosions contained fusospirochetal organisms, Cryptococcus neoformans, and another unidentified fungus.

Acquired Immunodeficiency Syndrome↗
PubMed1989

Identification of Taenia solium antigens in cerebrospinal fluid and larval antigens from patients with neurocysticercosis.

Two antigens (190 and 230 kDa) of the larvae of Taenia solium were detected in the cerebrospinal fluid (CSF) of 14 of 18 patients in which neurocysticercosis was suspected. Nine of these were confirmed by histopathology. Seven antigens were detected in cyst fluid of T. solium larvae removed from the brains of 6 infected patients. Two of these antigens had the same Mr as the T. solium antigens detected in the CSF. Polyacrylamide gel electrophoresis and electro-immunoblotting analyses were used for the identification and characterization. Antibodies in rabbit anti-larval antiserum and antibodies in sera of infected individuals recognized the same larval antigens in the larval cyst fluids and in the CSF of infected patients.

Animals↗