Detection of fetal hemoglobin in stool specimens and differentiation from maternal hemoglobin.
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Biomedical subjects
Publications and source records attributed to J A Hathaway.
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A cross-sectional spidemiologic study was conducted to investigate a cluster of three cases of systemic lupus erythematosus at one munitions plant. The study demonstrated no excess of autoimmune disease and also failed to identify any abnormalities of the hematologic, hepatic, or renal systems in employees with 8 hour time-weighted exposures to RDX of up to 1.57 mg/m3 (average exposure was 0.28 mg/m3).
The scientific and medical literature on TNT was reviewed with emphasis on studies providing correlation between work exposures and adverse health effects. Numerous adverse effects including upper respiratory and gastrointestinal complaints, anemia, liver function abnormalities, and possibly aplastic anemia have been noted at TNT levels below the current standard of 1.5 mg/m3. Mild biological effects, particularly reduction in hemoglobin levels or red blood cell counts, have been noted at exposures as low as 0.2 mg/m3. A workplace standard of 0.5 mg/m3 as an 8 hour time-weighted exposure is suggested for protection against adverse health effects.
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