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Biomedical subjects

J A Key

Publications and source records attributed to J A Key.

14 recordsLinked to original sources
PubMed1987

Examination of sexually abused children.

The approach to the examination of sexually abused children differs from that of normal for sick children and also from that of adults who have been the victims of rape. While the physical and psychological welfare of the patient must be the prime concern, medico-legal aspects are equally important. In the interests of the patient the initial examination and subsequent management and follow-up should be done by those with specific skills and with the support of members of disciplines essential to the total management of the complex and not uncommon problem of sexual abuse in children.

Adolescent↗
PubMed1987

Pulmonary function in sickle cell trait.

Pulmonary function abnormalities, which have been reported to occur in persons with sickle cell trait (hemoglobin AS), could intensify the hypoxic stimulus for the systemic formation of sickle cells at high altitude. We sought to determine whether pulmonary function abnormalities occur as a result of exposure to high altitudes in persons with hemoglobin AS. In a prospective study, 13 men with hemoglobin AS ("cases") and 13 controls (hemoglobin AA) matched by age, sex, and race were exposed to five to seven altitude simulations (ranging from 1524 to 7620 m [5000 to 25,000 ft]) in a hypobaric chamber. Measurements of diffusing capacity for carbon monoxide (DLco), forced vital capacity, forced expiratory volume in one second, and forced midexpiratory flow were obtained before and after each exposure. Data before exposures did not differ statistically between cases and controls. Altitude had no systematic effect on DLco or spirometric values in cases compared with values in controls (p greater than 0.05). Individual declines in forced vital capacity or DLco of more than 10% occurred with similar frequency in both groups. Measurements made after the series of exposures showed no change from those made before. We conclude that short serial exposures to hypoxia at high altitudes does not acutely or cumulatively alter DLco or spirometric values in healthy, nonexercising persons with sickle cell trait.

Adult↗
PubMed1980

The healthier heart.

Explore the source record for details and available documents.

Cardiac Surgical Procedures↗
PubMed1980

Transluminal dilatation in the treatment of peripheral arterial occlusive disease.

The authors review their experience over a 2-year period with transluminal arterial dilatation using the Grüntzig catheter. In 96 patients 136 aortoiliac or femoropopliteal arterial segments were dilated. The success rates at 1 year were 76% and 70%, respectively, for aortoiliac and femoropopliteal dilatations. The early and late results indicate that this procedure is useful in managing peripheral arterial occlusive disease in certain patients and that there are few complications when the procedure is carried out by a skilled angiographer.

Aortic Diseases↗
PubMed1978

Profundoplasty for limb salvage.

Profundoplasty was performed in 26 legs because of rest pain or gangrene; previous arterial reconstruction had been done in 12 of them. In 16 limbs the popliteotibial segment was patent; profundoplasty was successful in each case. In 10 limbs the popliteotibial segment was occluded, and profundoplasty failed in one instance. One patient died. The authors believe that re-establishing blood flow and pressure to the deep femoral artery, especially to the descending branch of the lateral circumflex artery and the distal part of the deep femoral artery can effectively improve the condition of ischemic legs.

Adult↗
PubMed1978

Phenol sympathectomy for vascular occlusive disease.

Surgical lumbar sympathectomy is often performed as a last resort in treating peripheral vascular occlusive disease. However, the variable success rate and the morbidity of this procedure prompted us to examine phenol sympathectomy and to elucidate the factors which can be used to predict success with the procedure. During the past three years, 127 phenol sympathectomies have been performed for peripheral vascular disease using a standard technique. The technique has proved simple and harmless. The results of a prospective study of 52 patients indicate that it is possible to predict the chance of success after this procedure by using a combination of clinical criteria and systolic pressure measurements at the ankle. A good response is anticipated in patients with rest pain or night pain if the systolic pressure at the ankle is greater than 35 millimeters of mercury. Patients with gangrene of the digits responded if the pressure at the ankle was greater than 60 millimeters of mercury.

Arterial Occlusive Diseases↗