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Biomedical subjects

J A Kirk

Publications and source records attributed to J A Kirk.

7 recordsLinked to original sources
PubMed1976

Physiotherapy and the frozen shoulder: a comparative trial of ice and ultrasonic therapy.

In a prospective study ice and ultrasonic applications have been compared in a series of patients with the frozen shoulder syndrome. No significant advantage of one treatment over the other could be demonstrated. It would appear that both of these physiotherapy methods can shorten the painful stage of the condition and, in conjunction with specific exercises, hasten recovery of the range of shoulder movement.

Adult↗
PubMed1976

Synovial fluid in the calf.

While awareness of synovial rupture of the knee joint confirmed by early arthrography increases, concomitant deep-vein occlusion may be being overlooked. Two cases of this are described, illustrating different mechanisms of venous occlusion by synovial rupture. Early thrombosis occurred in one patient from direct pressure as a result of haematoma following anticoagulant therapy and in another due to presumed external irritation of the vein. Although isolated bursae do not apparently rupture, tendon sheaths occasionally do. An example of lateral popliteal mononeuritis as a result of rupture of a tense peroneal tendon sheath is also given. Synovial rupture is primarily a clinical diagnosis but in selected cases, deep calf venography may be useful rather than arthrography. Almost a century ago, William Morrant Baker published his work on synovial protrusions showing his awareness of the consequences of free fluid in the calf. Some comments are made on his life and work.

Female↗
PubMed1975

E and EAC rosetting lymphocytes in patients with carcinoma of bronchus I. Some parameters of the test and of its prognostic significance.

Using peripheral blood lymphocytes separated by a Ficoll method and suspended in saline, means of 77-1% (s.d. 5-2) E rosettes (T lymphocytes) and 20-1% (s.d. 6-7) EAC rosettes (B lymphocytes) have been obtained with normal healthy donors. Poorer E-rosette formation resulted from higher centrifugation speeds during the washing of lymphocytes or erythrocytes, insufficient chilling, or rough handling. The presence of 5% albumin in the final mixture stabilized the rosettes and brought a constant subpopulation of B lymphocytes into rosetting. In patients with bronchial carcinoma who, at the time of diagnosis, had E-rosette percentages below 1 s.d. of the mean for normal donors, the length of survival was significantly shorter than in those with normal or high values. The same was true for those in whom null cells were detected. In each case the correlation effect was mainly found in the group of patients with squamous carcinoma.

B-Lymphocytes↗
PubMed1975

E and EAC rosetting lymphocytes in patients with carcinoma of bronchus. II. A sequential study of thirty patients: effect of BCG.

T and B lymphocytes have been estimated in thirty patients with carcinoma of bronchus at monthly intervals. The patients have been treated by surgery, radiotherapy or no conventional antineoplastic therapy, with or without monthly intradermal BCG. Significant increase in T-lymphocyte percentages occurred in three out of six patients treated by BCG and no conventional therapy, and similar increases were observed in other BCG-treated patients. Patterns emerged suggesting that the T-lymphocyte percentage may be depressed, directly or indirectly, by tumour and recover after surgery or palliative radiotherapy; that high T-lymphocyte levels may accompany reactive lymphocytosis to tumour and that T-lymphocyte collapse was associated with, and appeared to precede terminal clinical deterioration in many patients.

B-Lymphocytes↗