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Biomedical subjects

J A Maxwell

Publications and source records attributed to J A Maxwell.

10 recordsLinked to original sources

Adult "congenital" bilateral occlusion of the foramina of Monro.

Bilateral occlusion of the foramina of Monro was detected and treated in a hydrocephalic adult who developed rapid striking recent memory loss. She was treated by midline windowing of the third ventricle into the dilated lateral ventricles at a location 2 cm posterior to the occluded foramina of Monro. No inflammation was present. A biopsy specimen showed no evidence of malignancy. A reservoir was placed for long-term measurement of intraventricular pressure. Ten-year follow-up with pressure measurements, serial computed tomography scans, and magnetic resonance imaging showed no evidence of tumor.

Cerebral Ventricles

The occurrence and apparent effect on reproduction of a constriction of the vagina in the merino ewe.

The incidence and effect on reproduction of a constriction of the vagina was studied in 12 maiden merino flocks on 5 commercial properties in Western Australia. The overall incidence of the constriction was 11% with a range of from 2% to 27%. Ewes with a constriction of the vagina exhibited inferior reproductive capacity; fewer ewes lambed and of those that did fewer reared their lambs. A higher lamb mortality was recorded in lambs born to such ewes.

Animals

Effect of dexamethasone on experimental brain edema in cats.

The authors studied the effects of dexamethasone, 0.3 mg/kg/hr administered intravenously beginning 1 hour before injury, in adult cats with brain edema secondary to cold-induced cortical lesions. Edema was quantitatively measured in cortex, gyral white matter, and central (deep) white matter at 3, 24, 48, and 72 hours, with and without dexamethasone, by determining specific gravity (density) of samples in a continuous gradient column. Cold-induced lesions resulted in edema, which was greatest in the white matter of the injured hemisphere but also present in the contralateral hemisphere. Except for a slight but significant increase in density (decreased edema) of cortex at 24 hours, dexamethasone therapy resulted in no reduction of cold-induced edema, and in some cases increased the edema.

Animals

Mycotic aneurysm of the internal carotid artery in an unusual intra-cranial location.

A child is reported who developed a mycotic aneurysm of the cavernous portion of the internal carotid artery following staphylococcal cellulitis and septicemia. The unique feature of this case was the conspicuous absence of clinical or arteriographic evidence of carvernous sinus thrombosis. The pathogenesis of mycotic aneurysms is discussed.

Aneurysm, Infected

Ganglia of the nerve. Presentation of two unusual cases, a review of the literature, and a discussion of pathogenesis.

Two cases of intraneural ganglia are reported: the first reported involvement of the sciatic nerve and the first reported involvement of the tibial nerve in the tarsal tunnel. Both were successfully treated by excision with sparing the neural elements leading to neurological recovery. A review of the literature fails to reveal any consensus that lesions arise from normal synovial cavities. Incision, evacuation, and complete excision under magnification sparing neural elements gives satisfactory results. Excision of the nerve is not indicated. Pathologic examination suggests that the lesion arises by multicentric metaplasia of connective tissue elements of the nerve rather than by invasion.

Adult