PubMed Health⌕ Search

Biomedical subjects

J A Morrison

Publications and source records attributed to J A Morrison.

At least 19 recordsLinked to original sources
PubMed1992

Articulation testing versus conversational speech sampling.

Detailed speech analyses were performed on data from 61 speech-delayed children assessed by both a standard articulation test and a conversational speech sample. Statistically significant differences between the articulation accuracy profiles obtained from the two sampling modes were observed at all linguistic levels examined, including overall accuracy, phonological processes, individual phonemes, manner features, error-type, word position, and allophones. Established sounds were often produced more accurately in conversational speech, whereas emerging sounds were often produced more accurately in response to articulation test stimuli. Error patterns involving word-to-word transitions were available only in the context of continuous speech. A pass-fail analysis indicated that the average subject would receive similar clinical decisions from articulation testing and conversational speech sampling on an average of 71% of consonant sounds. Analyses of demographic, language, and speech variables did not yield any subject characteristics that were significantly associated with concordance rates in the two sampling modes. Discussion considers sources of variance for differences between sampling modes, including processes associated with both the speaker and the transcriber. In comparison to the validity of conversational speech samples for integrated speech, language, and prosodic analyses, articulation tests appear to yield neither typical nor optimal measures of speech performance.

Child↗
PubMed1991

Acne vulgaris in early adolescent boys. Correlations with pubertal maturation and age.

To assess the prevalence and severity of acne vulgaris in young adolescent boys, we studied 219 black and 249 white boys in fifth through ninth grades in Cincinnati, Ohio. The mean age was 12.2 +/- 1.4 years, with a range of 9 to 15 years. Pubertal maturation was scored as Tanner pubic hair stages (PH I to V) and pubertal stages (PS I to IV) that included testicular volume assessment. Acne was scored by number of comedonal (open plus closed comedones) and inflammatory (papules plus pustules) lesions. Comedonal and inflammatory lesions were analyzed separately and evaluated both as numerical scores and as grades (1, less than or equal to 10 lesions; 2, 11 to 25 lesions; and 3, greater than or equal to 26 lesions). Grades 2 and 3 were considered clinically significant acne. Acne became progressively more severe with advancing maturity. Mean acne scores correlated better with PS and pubic hair than with age. Black subjects were more mature than white subjects. Black boys in PSI and II had significantly more comedones than white boys; white boys had significantly more inflammatory lesions at PS I and III. Clinically significant comedonal acne was already present in PS I and occurred in 100% of boys in PS IV. In contrast, no boys at PS I and only 50% at PS IV had significant inflammatory acne. Midfacial acne dominated. We concluded that acne prevalence and severity correlate well with advancing pubertal maturation in young adolescent boys. Comedonal acne was more frequent and severe than inflammatory disease. Awareness of the extent and severity of acne in preadolescents and young adolescents may ultimately provide rationale for early intervention and thus prevention of severe acne vulgaris.

Acne Vulgaris↗
PubMed1991

Preventive practices for adult cardiovascular disease in children.

BACKGROUND: Differences between family practitioners and pediatricians regarding appropriate interventions for cardiovascular disease prevention in pediatric patients have been described by national surveys of physicians in the two specialties. the purpose of the study reported here was to determine whether similar differences existed in a more complete sample from a confined geographical area in which local standards of care might influence physicians practicing in the locale. METHODS: Members of the Southwestern Ohio Society of Family Physicians and the Cincinnati Pediatric Society were surveyed by questionnaire about their attitudes and practices concerning cardiovascular risk factors in children. The response rate was greater than 70% in each specialty group. RESULTS: Differences in the diagnosis and treatment of hypercholesterolemia were detected: (1) pediatricians screened patients at younger ages and used lower cutoff points for diagnosis (5.0 vs 5.5 mmol/L [192 vs 211 mg/dL]); and (2) family physicians were more likely to treat with medication (57% vs 5%), whereas pediatricians referred hypercholesterolemic patients to specialists more often (71% vs 19%). Both family physicians and pediatricians mislabeled blood pressures at the age-specific 90th percentile as normal (21% and 14%, respectively); this occurred more commonly with younger patients. Blood pressure was the risk factor most often measured, but smoking was the risk factor that received the most counseling by physicians in both specialties. CONCLUSIONS: Both family physicians and pediatricians reported feeling inadequately prepared to counsel lifestyle changes, and ranked obesity, smoking, and cholesterol as topics of greatest interest for continuing medical education courses. Physicians in both specialties did not routinely update family history of cardiovascular disease during well-child visits.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

Hormonal studies and physical maturation in adolescent gynecomastia.

As part of a 3-year longitudinal study of lipid and hormonal changes during puberty, 536 boys aged 10 to 15 years were prospectively followed every 6 months to assess development of gynecomastia. The overall prevalence of gynecomastia in the 377 with complete data was 48.5% (51% of white subjects and 46% of black subjects). In the majority of subjects, gynecomastia developed during mid-puberty. Gynecomastia was bilateral in 55% of subjects, on the left side in 19%, and on the right in 26%. Gynecomastia was documented for only one visit in the majority of subjects. When subjects were matched at the onset of gynecomastia for race, visit number, and pubertal rating, there were no significant differences between those with or without gynecomastia in serum estradiol level, testosterone level, estrogen/testosterone, ratio, or dehydroepiandrosterone-sulfate level. However, free testosterone level, weight, and Quetelet index were all significantly lower, and the testosterone-estrogen binding globulin level was significantly greater, in those with gynecomastia. We conclude that approximately half of adolescent boys have transient gynecomastia, usually lasting less than 1 year; those with gynecomastia enter mid-puberty at an earlier age, have a lower Quetelet index, and have lower serum free testosterone levels.

Adolescent↗
PubMed1989

Comparison of potassium hydroxide digestion and a modified Kato technique for the semi-quantitative estimation of Schistosoma mansoni eggs in faeces.

A simple method for the semi-quantitative estimation of eggs of Schistosoma mansoni in stools, based on digestion of faeces in 4% potassium hydroxide (KOH), is described. The relative performance of KOH digestion and a modified Kato method showed that the former was more sensitive and that the KOH/Kato ratio for the geometric mean number of eggs per gram, in stools positive by both methods, was 3.51.

Feces↗
PubMed1989

Reproductive outcomes of pregnant workers employed at 36 reinforced plastics companies. II. Lowered birth weight.

The authors analyzed the birth weights of infants whose mothers worked during pregnancy in the reinforced plastics industry, where styrene monomer is a primary chemical exposure. Reproductive and work histories were taken by telephone interview from 1535 women employed between 1974 and 1981 at 36 companies. The questionnaire was based on one used by the National Institute for Occupational Safety and Health, and indices of styrene exposure were derived from an historical set of 1500 industrial hygiene samples from the study companies. There was not a significant dose-response trend in decreasing average birth weights. However, women who worked at the most highly exposed jobs--such as laminators, rollers, or spray-up operators at boat manufacturing companies--had offspring with adjusted birth weights of 4% less than the offspring of unexposed women (95% confidence interval = -7.7% to +0.6%) after adjustment for other factors.

Birth Weight↗
PubMed1979

Piperacillin kinetics.

Piperacillin was administered to normal, healthy volunteers by an intravenous infusion over 30 min at dosage regimens of 12 gm daily (4 gm every 8 hr) and 24 gm daily (6 gm every 6 hr) for 5 consecutive days. Mean peak serum level after 12 gm daily was 244 +/- 24 (SE) microgram/ml and after 24 gm daily, 353 +/- 7 microgram/ml. After infusion the serum level declined monoexponentially in most subjects. On the 12-gm daily dosage mean values were 60 min for half-life (t1/2), 16 1 for volume of distribution, 188 ml/min for body clearance, and 139 ml/min for renal clearance. The same values on day 4 were 47 min, 12 1, 181 ml/min, and 125 ml/min; the volume of distribution was lower than on day 1. On the 24-gm daily dosage regimen, t1/2 was 60 min; volume of distribution, 16 1; body clearance, 183 ml/min; and renal clearance, 101 ml/min on day 1 compared to 68 min, 15 1, 148 ml/min, and 71 ml/min on day 4, the last 2 being significantly lower than on day 1. High renal clearance values were observed at low serum concentrations and vice versa, suggesting saturation of the tubular secretion process at high piperacillin concentrations in serum.

Adolescent↗
PubMed1979

Cigarette smoking, alcohol intake, and oral contraceptives: relationships to lipids and lipoproteins in adolescent school-children.

The effects of cigarette smoking, alcohol intake, and oral contraceptives on plasma cholesterol, triglyceride, high density lipoprotein cholesterol (C-HDL), and low density lipoprotein cholesterol (C-LDL) were assessed in 965 12--19-year-old school-children in the Cincinnati Lipid Research Clinic's Princeton school survey. After pair matching for age, sex, race, and total plasma cholesterol, adolescent children who smoked had mean C-HDL 6.1 mg/dl lower, and mean C-LDL 4.1 mg/dl higher, than nonsmokers (p less than 0.01). These findings for C-HDL were replicated by covariance analysis, adjusting for age, race, sex, alcohol intake, and triglyceride levels. Adolescents who drank alcohol had higher C-HDL and triglyceride levels and lower C-LDL than nondrinkers, but the differences were not significant. Adolescent females taking oral contraceptives had higher triglyceride, C-HDL, and C-LDL levels than matched controls, but the differences were not significant. If a portion of smoking's contribution to coronary heart disease risk is mediated through its inverse association with C-HDL, and if smoking habits initiated in adolescence continue into adulthood, this report provides additional physiologic data relevant to programs designed to prevent, reduce, or stop cigarette smoking in the adolescent years.

Adolescent↗
PubMed1979

Lipid and lipoprotein tracking in children.

Prospective studies in adults reveal that CHD risk is continuously related to total and LDL cholesterol levels (positively) and to HDL cholesterol levels (inversely) throughout their entire distribution. Such findings raise the possibility that children who tend to track in the lowest and highest decile for total and LDL cholesterol may mature to become adults respectively at reduced and increased CHD risk. Children who tend to track in the lowest and highest deciles for HDL cholesterol may also mature to become adults respectively at increased and reduced CHD risk. Although the degree of tracking at either extreme of the distribution, and for the group as a whole, appears to have adquate cohesiveness to be useful for prediction of future lipid and lipoprotein levels, individual children at the extremes of the distributions will need to be followed over longer periods of time, to identify the continuity of childhood and adult values, and eventual CHD risk.

Adolescent↗
PubMed1978

Traumatic intrapericardial rupture of the diaphragm.

A 60 year-old woman sustained an intrapericardial rupture of the diaphragm with herniation of a loop of transverse colon into the pericardium. There are ten previous reports of this condition. Reduction of the hernia and repair of the defect were readily accomplished through an upper midline abdominal incision.

Colonic Diseases↗