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Biomedical subjects

J A Neviackas

Publications and source records attributed to J A Neviackas.

9 recordsLinked to original sources
PubMed1981

Selective renal artery embolization for control of biopsy-induced bleeding.

Two cases of selective renal artery embolization for control of bleeding induced by arteriovenous malformation are described. Both cases occurred after percutaneous renal biopsy and involved massive hematuria, unresponsive to conservative treatment. Arteriography in both cases demonstrated an arteriovenous fistula in the area of the biopsy, and selective embolization with an artificial clot resulted in prompt cessation of bleeding. In one case, follow-up angiograms showed a minimal anatomic defect, and renal function studies were unchanged. Selective renal artery embolization is an acceptable method for correcting bleeding due to biopsy-induced arteriovenous malformation.

Adult↗
PubMed1981

Renal function abnormalities induced by marathon running.

To assess renal function changes induced by marathon racing in asymptomatic runners, we studied them before, six hours after, and one week after warm and cold weather marathons (26.2 miles [42 km]). Standard serum electrolytes, creatine phosphokinase (CPK), urinalysis, urinary myoglobin, and renal function tests (para-aminohippurate [PAH], inulin, and true creatinine clearances) were performed. After rehydration to their prerace weight, the subjects showed no postrace change in serum electrolytes. The CPK rose postrace and was two to three times higher in the warm weather runners than in the cold weather runners. All postrace urinalyses were grossly abnormal. Urinary myoglobins were positive postrace in warm weather runners and negative in cold weather runners. Warm weather runners showed a 50% decline in inulin clearance postrace but maintained PAH clearance. At one week, inulin clearance returned to baseline but fractional excretion of creatinine was below unity. In contrast, cold weather runners showed no change in inulin and PAH clearances postrace or at one week, but fractional excretion or creatinine postrace was less than unity returning to baseline at one week. We conclude that renal function abnormalities occur in marathon runners and that the severity of the abnormality is temperature-dependent.

Acute Kidney Injury↗
PubMed1981

Primary necrotizing arteritis of the main renal artery presenting as accelerated renovascular hypertension.

Presented is a unique case of accelerated hypertension in a 26-year-old black man. Clinically, the patient was found to have a left renal artery lesion and lateralizing renal vein renins. At surgery, a stenosing lesion was found in the artery supplying the upper pole of the left kidney. This was caused by a densely fibrotic mass involving the main renal artery. Microscopy revealed a necrotizing arteritis with no other arteries involved. This case of primary necrotizing arteritis of the main renal artery appears to represent a new entity because of its pathological and clinical differences with the known forms of large vessel arteritis. It is possible that this may represent a particularly acute and necrotizing stage of Takayasu's aortitis, or an extremely rare case of classical periarteritis nodosa confined solely to the main renal artery. The renin tissue assays document the hyperreninemia produced by arterial stenosis. The differential diagnosis of the lesion is considered, and the pathophysiology of hypertension due to large vessel arteritis is discussed.

Adult↗
PubMed1976

Histologic and ultrastructural studies of canine pancreas fed an elemental diet.

A clinically available elemental diet (Vivonex-100) has been fed to healthy mongrel dogs. Compared to a regular chow diet and regulated so as to maintain a stable weight, no changes were noted on light or electron microscopy and six months' maintenance. Extrapolating, the pancreas shows no evidence of a "resting state" according to this data.

Amino Acids↗
PubMed1976

Pancreatic enzyme response with an elemental diet.

Elemental diets can maintain or slightly improve the nutritional status without a major stimulatory effect on the pancreas. Six dogs were maintained with a regular chow diet, switched to an elemental diet and, subsequently, returned to a chow diet. Cannulation of the pancreatic duct through a duodenal cutaneous fistula revealed the enzyme response to be decreased in a dog maintained with an elemental diet, with no or only a slight weight gain. Return to a regular diet resulted in a return of pancreatic enzyme response.

Amino Acids↗