Biomedical subjects
Publications and source records attributed to J A Ramos-Brieva.
This paper investigates the reliability and validity of a Spanish version of the Hamilton Rating Scale for Depression (17-item version) which has good concurrent (r = 0.82) and content (average frequency = 62%) validity. Inter-rater reliability (r = 0.99), split-half reliability (r = 0.89) and alpha reliability (r = 0.72) are acceptable. A Factor Analysis identified five factors accounting for 56% of total variance.
A study was done on 40 outpatients suffering from major affective disorders (uni- and bipolar). Chlorimipramine or maprotiline was administered alternatively (means = 116.25 and 116.75 mg/day, respectively). The therapeutic effect of both antidepressive drugs is very similar, but maprotiline improves the gastrointestinal somatic symptoms faster and seems to be more effective in bipolar patients. It also produces less side effects than chlorimipramine.
A line-bisection test was applied in order to detect the presence of right hemisphere dysfunction in patients with Major Affective Disorder (Nonpsychotic Major Depression). Depressive patients and control subjects did not differ in perception of the midpoint of the line. Both groups differed in dispersion to the mean value with the depressive patients showing less precision. These data are not supportive of the notion of a right hemisphere dysfunction in the depressive disorder.
Do bipolar I and bipolar II subtypes represent two different forms of affective illness in terms of course? To test this working hypothesis, a comparison was made of data on course of bipolar I (n = 84) and bipolar II (n = 16) subgroups from 100 consecutive in-patients diagnosed as bipolar affective disorder. The two subgroups differed significantly regarding course. The patients of the bipolar II group had significantly later first admissions, more episodes, more prolonged mean duration of phase and shorter mean duration of intervals. In bipolar I group, a greater frequency of manic phases was found.
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This paper reports a comparative study of medical depressed inpatients. A total of 100 medical depressed cases were screened and compared with those of a control sample of 100 depressed inpatients in a psychiatric unit. Diagnostic information was obtained from records. Comparisons on a number of demographic variables show no difference on age, sex, socioeconomic class and marital status. The most striking differences between psychiatric depression and medical depression were on the clinical features, having the medical sample more anxious and hypochondriachal types and less delusional and retarded cases. Medical depressives patients were less prone to report suicidal feelings. Recognition of the depressive syndromes by the staff of the medical wards was poor. Somatic symptoms form a prominent part of the symptomatology of the medical depression.
Since the time of Kraepelin, in continental Europe the sadness of depression has been considered to have a "distinct quality' basic to the diagnosis of pathological depression. This distinct quality has been interpreted by observers but patients have been noted to have difficulty verbalizing differences from normal sadness. The authors have used a discriminant analysis to study how patients define pathological sadness and as a result have developed a Pathological Sadness Index with a sensitivity of 0.94, a specificity of 0.96 and a total misclassification rate of 5% (kappa w = 0.90).
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.