Hemodynamic evaluation of the Beall mitral valve prosthesis.
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Biomedical subjects
Publications and source records attributed to J A Reid.
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Severe oral hypersensitivity and aversive oral behaviors present a significant barrier to dental treatment and compromise oral health status. Although several authors have addressed the reduction of oral hypersensitivity and aversive behaviors (such as gagging, retching, and vomiting) in the otherwise well dental patient, treatment for patients with severe disability has not been explored. The successful management of oral hypersensitivity and aversive behavior can have significant health benefits. These can be described via an outcomes paradigm as physical and social benefits for the patient, psychological benefits for the patient, carer, and practitioner, and organizational benefits for the institutions providing dental care and medical management. This paper summarizes the management of a severely disabled patient whose aversive behaviors were eliminated with non-invasive therapy techniques. Oral hygiene was facilitated and health benefits were identified across a number of domains following successful multi-disciplinary management.
CDC WONDER is an information management architecture designed for public health. It provides access to information and communications without the user's needing to know the location of data or communication pathways and mechanisms. CDC WONDER users have access to extractions from some 40 databases; electronic mail (e-mail); and surveillance data processing. System components include the Remote Client, the Communications Server, the Queue Managers, and Data Servers and Process Servers. The Remote Client software resides in the user's machine; other components are at the Centers for Disease Control and Prevention (CDC). The Remote Client, the Communications Server, and the Applications Server provide access to the information and functions in the Data Servers and Process Servers. The system architecture is based on cooperative processing, and components are coupled via pure message passing, using several protocols. This architecture allows flexibility in the choice of hardware and software. One system limitation is that final results from some subsystems are obtained slowly. Although designed for public health, CDC WONDER could be useful for other disciplines that need flexible, integrated information exchange.
There is a growing interest in the potential benefits to be obtained from closed-loop control of drug infusion [1-5]. The most widely available infusion pump which is specifically designed for control by computer is the 929 volumetric infusion pump produced by Imed. The increasing availability of microcomputers suggests that they will be used more frequently to control such pumps. However, difficulties can arise when the attempt is made to establish communication between the computer and the pump [6] and a method employed for this purpose is described in this article. The aim was to provide a simple method of conducting the required communication between the computer and the pump using a high-level language. The commands specified in the high-level language are passed to a machine-code subroutine which organizes transmission to and receives data from the pump.
Machine code programs have been produced to allow a simple method of communication between a computer and the Braun Infusomat pump. Commands are set up as character strings using a high-level language and passed to a machine code program which transmits them to the pump. Messages from the pump are received under interrupt control for display by the high-level language. Any error in communication is stored in memory and the appropriate action taken by the main application program.
Tissue samples are digested under hot alkaline conditions after initial conditioning at room temperature with phosphate-buffered saline. The cooled digest is deproteinated with concentrated perchloric acid. After centrifugation and pH adjustment, the clear supernatant is applied to an ion-exchange cartridge, and after the cartridge is washed, the neomycin is eluted with dilute perchloric acid. This eluate is derivatized with 9-fluorenylmethyl chloroformate prior to liquid chromatography using a wide-pore spherical silica C4 column and fluorescence detection. Recovery and repeatability are calculated from tissue extract standard calibration curves produced from the same assay. Recoveries ranged from 80 to 120% for fortifications of 0.25-1.00 mg/kg for muscle tissue and from 80 to 100% for fortifications of 0.50-10.0 mg/kg for kidney tissue. Limits of quantitation were 0.25 and 0.50 mg/kg, respectively, for muscle and kidney tissues. Limits of detection were 0.125 and 0.20 mg/kg, respectively, for muscle and kidney tissues.
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This article is based on the proceedings of the conference 'Appraisal: purpose, pitfalls and good practice,' held at the Royal College of Physicians of London in May 1996. The conference brought together not only doctors but also representatives of other professions, to review the role of appraisal in education and industry, and to discuss how it might be applied in the medical field.